CD133 (Prominin-1) Monoclonal Antibody (TMP4), PE, eBioscience™ | Invitrogen 12-1338-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD133 (Prominin-1) Monoclonal Antibody (TMP4), PE, eBioscience™

catalog :

12-1338-42

quantity :

100 Tests

price :

US 400

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

TMP4

reactivity :

human

application :

flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...; fig 7a flow cytometry; human; loading ...; fig 5a	Huang W, Bei L, Eklund E. Inhibition of Fas associated phosphatase 1 (Fap1) facilitates apoptosis of colon cancer stem cells and enhances the effects of oxaliplatin. Oncotarget. 2018;9:25891-25902 pubmed publisher
	Liu Z, Lei J, Wu T, Hu W, Zheng M, Wang Y, et al. Lipogenesis promotes mitochondrial fusion and maintains cancer stemness in human NSCLC. JCI Insight. 2023;8: pubmed publisher
	Tu X, Li C, Sun W, Tian X, Li Q, Wang S, et al. Suppression of Cancer Cell Stemness and Drug Resistance via MYC Destabilization by Deubiquitinase USP45 Inhibition with a Natural Small Molecule. Cancers (Basel). 2023;15: pubmed publisher
	Pasquale V, Ducci G, Campioni G, Ventrici A, Assalini C, Busti S, et al. Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties. Cells. 2020;9: pubmed publisher
	Jia J, Yu F, Xiong Y, Wei W, Ma H, Nisi F, et al. Chemerin enhances the adhesion and migration of human endothelial progenitor cells and increases lipid accumulation in mice with atherosclerosis. Lipids Health Dis. 2020;19:207 pubmed publisher
	Li F, Hu Q, He T, Xu J, Yi Y, Xie S, et al. The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness. Cancers (Basel). 2020;12: pubmed publisher
	Aerts Kaya F, Visser T, Pervin B, Mammadova A, Ozyuncu O, Wagemaker G, et al. SUL-109 Protects Hematopoietic Stem Cells from Apoptosis Induced by Short-Term Hypothermic Preservation and Maintains Their Engraftment Potential. Biol Blood Marrow Transplant. 2020;26:634-642 pubmed publisher
	Wang F, Wang A, Chesnelong C, Yang Y, Nabbi A, Thalappilly S, et al. ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways. Oncogene. 2018;37:286-301 pubmed publisher
	Mei K, Du L, Yan M, Zhang Z, Zhang F, Gong L, et al. Modified Leukocyte Filter Removes Tumor Cells from the Salvaged Blood. PLoS ONE. 2015;10:e0130864 pubmed publisher
	Sahlberg S, Spiegelberg D, Glimelius B, Stenerlow B, Nestor M. Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells. PLoS ONE. 2014;9:e94621 pubmed publisher
	Khanjani S, Khanmohammadi M, Zarnani A, Akhondi M, Ahani A, Ghaempanah Z, et al. Comparative evaluation of differentiation potential of menstrual blood- versus bone marrow-derived stem cells into hepatocyte-like cells. PLoS ONE. 2014;9:e86075 pubmed publisher
	Lehmann C, Jobs G, Thomas M, Burtscher H, Kubbies M. Established breast cancer stem cell markers do not correlate with in vivo tumorigenicity of tumor-initiating cells. Int J Oncol. 2012;41:1932-42 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD133 (Prominin-1) Monoclonal Antibody (TMP4), PE, eBioscience™

Catalog # :

12-1338-42

Quantity :

100 Tests

Price :

US 400

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

TMP4

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

The CD133 (AC133) antigen is a 97 kDa glycoprotein, with 5 transmembrane domains, that shows up as a 120 kDa band on protein gels due to glycosylation. CD133 is a cell surface marker expressed by immature hematopoietic stem cells but not mature blood cells. In addition to hematopoietic stem and progenitor cells, CD133 has been found to be a marker for other stem and progenitor cells including neural and embryonic stem cells. CD133 has been shown to be expressed in cancers, including some leukemias and brain tumors, that may be derived from stem cells. Low level expression could also be detected in the kidney, pancreas, placenta, and fetal liver. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of the CD133 gene is also associated with several types of cancer. CD133 is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner, and multiple transcript variants encoding different isoforms have been found.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

4932416E19Rik; AC133; antigen AC133; Antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-like 1; Prominin-like protein 1; Proml1; RP41; STGD4

more info or order :

Invitrogen product webpage