product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD127 Monoclonal Antibody (A7R34), PE, eBioscience™
catalog :
12-1271-82
quantity :
100 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
A7R34
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 250
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s1a
Steer C, Mathä L, Shim H, Takei F. Lung group 2 innate lymphoid cells are trained by endogenous IL-33 in the neonatal period. JCI Insight. 2020;5: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2b
Qian L, Bajana S, Georgescu C, Peng V, Wang H, Adrianto I, et al. Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors. J Exp Med. 2019;216:884-899 pubmed publisher
  • flow cytometry; mouse; fig 1d
Szabo P, Goswami A, Mazzuca D, Kim K, O Gorman D, Hess D, et al. Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology. J Immunol. 2017;198:2805-2818 pubmed publisher
  • flow cytometry; mouse; fig 3
Braun J, Meixner A, Brachner A, Foisner R. The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis. PLoS ONE. 2016;11:e0152278 pubmed publisher
  • flow cytometry; mouse; fig 1, 2
Kim J, Choi Y, Lee B, Song M, Ban C, Kim J, et al. Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells. J Allergy Clin Immunol. 2016;137:1466-1476.e3 pubmed publisher
  • flow cytometry; mouse; fig s4
Li C, Li W, Xiao J, Jiao S, Teng F, Xue S, et al. ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy. EMBO Mol Med. 2015;7:754-69 pubmed publisher
  • flow cytometry; mouse; fig 3
Charlton J, Tsoukatou D, Mamalaki C, Chatzidakis I. Programmed death 1 regulates memory phenotype CD4 T cell accumulation, inhibits expansion of the effector memory phenotype subset and modulates production of effector cytokines. PLoS ONE. 2015;10:e0119200 pubmed publisher
  • flow cytometry; mouse
Mise Omata S, Alles N, Fukazawa T, Aoki K, Ohya K, Jimi E, et al. NF-?B RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation. Int Immunol. 2014;26:607-18 pubmed publisher
  • flow cytometry; mouse; tbl 1
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
  • flow cytometry; mouse; fig s3
Ota N, Wong K, Valdez P, Zheng Y, Crellin N, Diehl L, et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol. 2011;12:941-8 pubmed publisher
  • flow cytometry; mouse; fig 1
Fahl S, Crittenden R, Allman D, Bender T. c-Myb is required for pro-B cell differentiation. J Immunol. 2009;183:5582-92 pubmed publisher
Martin M, Sompallae R, Winborn C, Harty J, Badovinac V. Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross. Cell Rep. 2020;31:107508 pubmed publisher
Pokrovskii M, Hall J, Ochayon D, Yi R, Chaimowitz N, Seelamneni H, et al. Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells. Immunity. 2019;51:185-197.e6 pubmed publisher
Yamashita M, Passegue E. TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration. Cell Stem Cell. 2019;: pubmed publisher
Xu W, Cherrier D, Chea S, Vosshenrich C, Serafini N, Petit M, et al. An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials. Immunity. 2019;50:1054-1068.e3 pubmed publisher
Zhang Z, Huang Z, Ong B, Sahu C, Zeng H, Ruan H. Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis. Haematologica. 2019;: pubmed publisher
Šestan M, Marinović S, Kavazović I, Cekinović Đ, Wueest S, Turk Wensveen T, et al. Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity. Immunity. 2018;49:164-177.e6 pubmed publisher
Murera D, Arbogast F, Arnold J, Bouis D, Muller S, Gros F. CD4 T cell autophagy is integral to memory maintenance. Sci Rep. 2018;8:5951 pubmed publisher
Sun C, Lan P, Han Q, Huang M, Zhang Z, Xu G, et al. Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion. Nat Commun. 2018;9:1241 pubmed publisher
Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher
Luo B, Chen K, Feng Q, Xiao W, Ma D, Yang H, et al. The interplay of BMP4 and IL?7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia?reperfusion. Int J Mol Med. 2018;41:2640-2650 pubmed publisher
Wang Y, Xiao M, Tao C, Chen J, Wang Z, Yang J, et al. Inactivation of mTORC1 Signaling in Osterix-expressing Cells Impairs B-cell Differentiation. J Bone Miner Res. 2017;: pubmed publisher
Seshadri S, Allan D, Carlyle J, Zenewicz L. Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling. PLoS Pathog. 2017;13:e1006690 pubmed publisher
Asada N, Kunisaki Y, Pierce H, Wang Z, Fernandez N, Birbrair A, et al. Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nat Cell Biol. 2017;19:214-223 pubmed publisher
Dill R, Walker A. Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland. J Mammary Gland Biol Neoplasia. 2017;22:13-26 pubmed publisher
Barrett N, Malouf C, Kapeni C, Bacon W, Giotopoulos G, Jacobsen S, et al. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016;16:1039-1054 pubmed publisher
Boulter N, Suarez F, Schibeci S, Sunderland T, Tolhurst O, Hunter T, et al. A simple, accurate and universal method for quantification of PCR. BMC Biotechnol. 2016;16:27 pubmed publisher
Zhu N, Chen M, Eng R, DeJong J, Sinha A, Rahnamay N, et al. MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C. J Clin Invest. 2016;126:997-1011 pubmed publisher
Rak G, Osborne L, Siracusa M, Kim B, Wang K, Bayat A, et al. IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing. J Invest Dermatol. 2016;136:487-496 pubmed publisher
Pearson C, Thornton E, McKenzie B, Schaupp A, Huskens N, Griseri T, et al. ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation. elife. 2016;5:e10066 pubmed publisher
Jeong Ryu S, Ju J, Kim W, Bum Kim M, Hee Oh K, Sup Lee D, et al. Alleviation of skin inflammation after Lin(-) cell transplantation correlates with their differentiation into myeloid-derived suppressor cells. Sci Rep. 2015;5:14663 pubmed publisher
Laidlaw B, Cui W, Amezquita R, Gray S, Guan T, Lu Y, et al. Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells. Nat Immunol. 2015;16:871-9 pubmed publisher
Gandhapudi S, Tan C, Marino J, Taylor A, Pack C, Gaikwad J, et al. IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells. J Immunol. 2015;194:3820-8 pubmed publisher
Jensen K, Camejo A, Melo M, Cordeiro C, Julien L, Grotenbreg G, et al. Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination. MBio. 2015;6:e02280 pubmed publisher
Karamitros D, Patmanidi A, Kotantaki P, Potocnik A, Bähr Ivacevic T, Benes V, et al. Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development. 2015;142:70-81 pubmed publisher
Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, et al. A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice. J Immunol. 2015;194:243-51 pubmed publisher
Puleston D, Zhang H, Powell T, Lipina E, Sims S, Panse I, et al. Autophagy is a critical regulator of memory CD8(+) T cell formation. elife. 2014;3: pubmed publisher
Xia P, Wang S, Huang G, Zhu P, Li M, Ye B, et al. WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner. J Exp Med. 2014;211:2119-34 pubmed publisher
Salmond R, Brownlie R, Morrison V, Zamoyska R. The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals. Nat Immunol. 2014;15:875-883 pubmed publisher
Li J, Razumilava N, Gores G, Walters S, Mizuochi T, Mourya R, et al. Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation. J Clin Invest. 2014;124:3241-51 pubmed publisher
Nakada D, Oguro H, Levi B, Ryan N, Kitano A, Saitoh Y, et al. Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy. Nature. 2014;505:555-8 pubmed publisher
Cheng W, Wee K, Kollmann T, Dutz J. Topical CpG adjuvantation of a protein-based vaccine induces protective immunity to Listeria monocytogenes. Clin Vaccine Immunol. 2014;21:329-39 pubmed publisher
Kahlfuß S, Simma N, Mankiewicz J, Bose T, Lowinus T, Klein Hessling S, et al. Immunosuppression by N-methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells. Mol Cell Biol. 2014;34:820-31 pubmed publisher
Brinkhoff B, Ostroumov D, Heemcke J, Woller N, Gürlevik E, Manns M, et al. Microsphere priming facilitates induction of potent therapeutic T-cell immune responses against autochthonous liver cancers. Eur J Immunol. 2014;44:1213-24 pubmed publisher
Mollo S, Zajac A, Harrington L. Temporal requirements for B cells in the establishment of CD4 T cell memory. J Immunol. 2013;191:6052-9 pubmed publisher
Campaner S, Viale A, De Fazio S, Doni M, De Franco F, D Artista L, et al. A non-redundant function of cyclin E1 in hematopoietic stem cells. Cell Cycle. 2013;12:3663-72 pubmed publisher
Takahara M, Nemoto Y, Oshima S, Matsuzawa Y, Kanai T, Okamoto R, et al. IL-7 promotes long-term in vitro survival of unique long-lived memory subset generated from mucosal effector memory CD4+ T cells in chronic colitis mice. Immunol Lett. 2013;156:82-93 pubmed publisher
Maina V, Marrella V, Mantero S, Cassani B, Fontana E, Anselmo A, et al. Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration. J Leukoc Biol. 2013;94:1221-30 pubmed publisher
Mielke L, Groom J, Rankin L, Seillet C, Masson F, Putoczki T, et al. TCF-1 controls ILC2 and NKp46+ROR?t+ innate lymphocyte differentiation and protection in intestinal inflammation. J Immunol. 2013;191:4383-91 pubmed publisher
Prabhu N, Ho A, Wong K, Hutchinson P, Chua Y, Kandasamy M, et al. Gamma interferon regulates contraction of the influenza virus-specific CD8 T cell response and limits the size of the memory population. J Virol. 2013;87:12510-22 pubmed publisher
Rowe A, Murray S, Raué H, Koguchi Y, Slifka M, Parker D. A cell-intrinsic requirement for NF-?B-inducing kinase in CD4 and CD8 T cell memory. J Immunol. 2013;191:3663-72 pubmed publisher
Cooney L, Gupta M, Thomas S, Mikolajczak S, Choi K, Gibson C, et al. Short-lived effector CD8 T cells induced by genetically attenuated malaria parasite vaccination express CD11c. Infect Immun. 2013;81:4171-81 pubmed publisher
Beus J, Hashmi S, Selvaraj S, Duan D, Stempora L, Monday S, et al. Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. PLoS ONE. 2013;8:e71221 pubmed publisher
Li G, Yang Q, Zhu Y, Wang H, Chen X, Zhang X, et al. T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells. PLoS ONE. 2013;8:e67401 pubmed publisher
Bhadra R, Cobb D, Khan I. Donor CD8+ T cells prevent Toxoplasma gondii de-encystation but fail to rescue the exhausted endogenous CD8+ T cell population. Infect Immun. 2013;81:3414-25 pubmed publisher
Miyazaki Y, Tsumiyama K, Yamane T, Ito M, Shiozawa S. Expansion of PD-1-positive effector CD4 T cells in an experimental model of SLE: contribution to the self-organized criticality theory. Kobe J Med Sci. 2013;59:E64-71 pubmed
Spence P, Jarra W, Lévy P, Reid A, Chappell L, Brugat T, et al. Vector transmission regulates immune control of Plasmodium virulence. Nature. 2013;498:228-31 pubmed publisher
Shitara S, Hara T, Liang B, Wagatsuma K, Zuklys S, Hollander G, et al. IL-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCR??+ intraepithelial lymphocytes. J Immunol. 2013;190:6173-9 pubmed publisher
Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, et al. Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method. Biochem Biophys Res Commun. 2013;435:586-91 pubmed publisher
Nemoto Y, Kanai T, Takahara M, Oshima S, Okamoto R, Tsuchiya K, et al. Th1/Th17-mediated interstitial pneumonia in chronic colitis mice independent of intestinal microbiota. J Immunol. 2013;190:6616-25 pubmed publisher
Kamijo S, Takeda H, Tokura T, Suzuki M, Inui K, Hara M, et al. IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation. J Immunol. 2013;190:4489-99 pubmed publisher
Masson F, Minnich M, Olshansky M, Bilic I, Mount A, Kallies A, et al. Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation. J Immunol. 2013;190:4585-94 pubmed publisher
Pongratz G, Anthofer J, Melzer M, Anders S, Grassel S, Straub R. IL-7 receptor ? expressing B cells act proinflammatory in collagen-induced arthritis and are inhibited by sympathetic neurotransmitters. Ann Rheum Dis. 2014;73:306-12 pubmed publisher
Liu B, Wang M, Wang X, Zhao D, Liu D, Liu J, et al. Liver sinusoidal endothelial cell lectin inhibits CTL-dependent virus clearance in mouse models of viral hepatitis. J Immunol. 2013;190:4185-95 pubmed publisher
Daudelin J, Mathieu M, Boulet S, Labrecque N. IL-6 production by dendritic cells is dispensable for CD8+ memory T-cell generation. Biomed Res Int. 2013;2013:126189 pubmed publisher
Bell B, Kitajima M, Larson R, Stoklasek T, Dang K, Sakamoto K, et al. The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses. Nat Immunol. 2013;14:364-71 pubmed publisher
Jessen B, Bode S, Ammann S, Chakravorty S, Davies G, Diestelhorst J, et al. The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2. Blood. 2013;121:2943-51 pubmed publisher
Jiang J, Champion C, Wei B, Liu G, Kelly K. CD8?CXCR5? T cells regulate pathology in the genital tract. Infect Dis Obstet Gynecol. 2013;2013:813238 pubmed publisher
Yamamoto M, Seki Y, Iwai K, Ko I, Martin A, Tsuji N, et al. Ontogeny and localization of the cells produce IL-2 in healthy animals. Cytokine. 2013;61:831-41 pubmed publisher
Jeannet R, Cai Q, Liu H, Vu H, Kuo Y. Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal. Stem Cells. 2013;31:560-71 pubmed publisher
Franke K, Kalucka J, Mamlouk S, Singh R, Muschter A, Weidemann A, et al. HIF-1? is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2?-induced excessive erythropoiesis. Blood. 2013;121:1436-45 pubmed publisher
Hackstein H, Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N. Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res. 2012;13:94 pubmed publisher
Sato T, Chiba T, Ohno S, Sato C, Sugoh T, Miyashita K, et al. Reciprocal control of G1-phase progression is required for Th-POK/Runx3-mediated CD4/8 thymocyte cell fate decision. J Immunol. 2012;189:4426-36 pubmed publisher
Krishnamoorthy N, Khare A, Oriss T, Raundhal M, Morse C, Yarlagadda M, et al. Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma. Nat Med. 2012;18:1525-30 pubmed publisher
Baru A, Untucht C, Ganesh V, Hesse C, Mayer C, Sparwasser T. Optimal isolation of functional Foxp3+ induced regulatory T cells using DEREG mice. PLoS ONE. 2012;7:e44760 pubmed publisher
Van Belle T, Ling E, Haase C, Bresson D, Ursø B, Von Herrath M. NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes. J Autoimmun. 2013;40:66-73 pubmed publisher
Guo X, Jie Y, Ren D, Zeng H, Zhang Y, He Y, et al. In vitro-expanded CD4(+)CD25(high)Foxp3(+) regulatory T cells controls corneal allograft rejection. Hum Immunol. 2012;73:1061-7 pubmed publisher
Le Campion A, Pommier A, Delpoux A, Stouvenel L, Auffray C, Martin B, et al. IL-2 and IL-7 determine the homeostatic balance between the regulatory and conventional CD4+ T cell compartments during peripheral T cell reconstitution. J Immunol. 2012;189:3339-46 pubmed
Xu H, Menendez S, Schlegelberger B, Bae N, Aplan P, Göhring G, et al. Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model. Blood. 2012;120:3089-97 pubmed publisher
Owens B, Beattie L, Moore J, Brown N, Mann J, Dalton J, et al. IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c? cell populations during visceral leishmaniasis. PLoS Pathog. 2012;8:e1002827 pubmed publisher
Ligons D, Tuncer C, Linowes B, Akcay I, Kurtulus S, Deniz E, et al. CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1. J Biol Chem. 2012;287:34386-99 pubmed publisher
Pattacini L, Mize G, Graham J, Fluharty T, Graham T, Lingnau K, et al. A novel HIV vaccine adjuvanted by IC31 induces robust and persistent humoral and cellular immunity. PLoS ONE. 2012;7:e42163 pubmed publisher
Chang P, Lee S, Hu X, Davey G, Duan G, Cho J, et al. Breakdown in repression of IFN-? mRNA leads to accumulation of self-reactive effector CD8+ T cells. J Immunol. 2012;189:701-10 pubmed publisher
Gasparetto M, Sekulovic S, Zakaryan A, Imren S, Kent D, Humphries R, et al. Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status. Exp Hematol. 2012;40:857-66.e5 pubmed publisher
Pham N, Badovinac V, Harty J. Epitope specificity of memory CD8+ T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice. Eur J Immunol. 2012;42:1488-99 pubmed publisher
Kim G, Ligons D, Hong C, Luckey M, Keller H, Tai X, et al. An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis. J Immunol. 2012;188:5859-66 pubmed publisher
Pham N, Badovinac V, Harty J. Differential role of "Signal 3" inflammatory cytokines in regulating CD8 T cell expansion and differentiation in vivo. Front Immunol. 2011;2:4 pubmed publisher
Florian M, Dörr K, Niebel A, Daria D, Schrezenmeier H, Rojewski M, et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell. 2012;10:520-30 pubmed publisher
Alari Pahissa E, Vega Ramos J, Zhang J, Castaño A, Turley S, Villadangos J, et al. Differential effect of CD69 targeting on bystander and antigen-specific T cell proliferation. J Leukoc Biol. 2012;92:145-58 pubmed publisher
Notake T, Horisawa S, Sanjo H, Miyagawa S, Hida S, Taki S. Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors. J Immunol. 2012;188:4838-45 pubmed publisher
Sharma A, Chen Q, Nguyen T, Yu Q, Sen J. T cell factor-1 and β-catenin control the development of memory-like CD8 thymocytes. J Immunol. 2012;188:3859-68 pubmed publisher
Wilson J, Pack C, Lin E, Frost E, Albrecht J, Hadley A, et al. CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion. J Immunol. 2012;188:4340-8 pubmed publisher
Riley M, Zurenski M, Frazer L, O Connell C, Andrews C, Mintus M, et al. The recall response induced by genital challenge with Chlamydia muridarum protects the oviduct from pathology but not from reinfection. Infect Immun. 2012;80:2194-203 pubmed publisher
Jiang X, Clark R, Liu L, Wagers A, Fuhlbrigge R, Kupper T. Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature. 2012;483:227-31 pubmed publisher
Li Q, Rao R, Vazzana J, Goedegebuure P, Odunsi K, Gillanders W, et al. Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity. J Immunol. 2012;188:3080-7 pubmed publisher
Sugiyama M, Nakato G, Jinnohara T, Akiba H, Okumura K, Ohno H, et al. Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development. Int Immunol. 2012;24:369-78 pubmed publisher
Liu J, Mercher T, Scholl C, Brumme K, Gilliland D, Zhu N. A functional role for the histone demethylase UTX in normal and malignant hematopoietic cells. Exp Hematol. 2012;40:487-98.e3 pubmed publisher
Mathieu M, Cotta Grand N, Daudelin J, Boulet S, Lapointe R, Labrecque N. CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells. PLoS ONE. 2012;7:e30139 pubmed publisher
Iseki M, Omori Miyake M, Xu W, Sun X, Takaki S, Rawlings D, et al. Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4. Int Immunol. 2012;24:183-95 pubmed publisher
Ochiai K, Maienschein Cline M, Mandal M, Triggs J, Bertolino E, Sciammas R, et al. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol. 2012;13:300-7 pubmed publisher
Wong S, Walker J, Jolin H, Drynan L, Hams E, Camelo A, et al. Transcription factor ROR? is critical for nuocyte development. Nat Immunol. 2012;13:229-36 pubmed publisher
Tan J, O Neill H. Myelopoiesis in spleen-producing distinct dendritic-like cells. J Cell Mol Med. 2012;16:1924-33 pubmed publisher
Gonzaga R, Matzinger P, Perez Diez A. Resident peritoneal NK cells. J Immunol. 2011;187:6235-42 pubmed publisher
Yoshizawa K, Nakajima S, Notake T, Miyagawa S, Hida S, Taki S. IL-15-high-responder developing NK cells bearing Ly49 receptors in IL-15-/- mice. J Immunol. 2011;187:5162-9 pubmed publisher
Pearson C, Silva A, Saini M, Seddon B. IL-7 determines the homeostatic fitness of T cells by distinct mechanisms at different signalling thresholds in vivo. Eur J Immunol. 2011;41:3656-66 pubmed publisher
Wainwright D, Sengupta S, Han Y, Lesniak M. Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors. Neuro Oncol. 2011;13:1308-23 pubmed publisher
Corfe S, Rottapel R, Paige C. Modulation of IL-7 thresholds by SOCS proteins in developing B lineage cells. J Immunol. 2011;187:3499-510 pubmed publisher
Bertossi A, Aichinger M, Sansonetti P, Lech M, Neff F, Pal M, et al. Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med. 2011;208:1749-56 pubmed publisher
Reyes Sandoval A, Wyllie D, Bauza K, Milicic A, Forbes E, Rollier C, et al. CD8+ T effector memory cells protect against liver-stage malaria. J Immunol. 2011;187:1347-57 pubmed publisher
Lorenzo L, Chen H, Shatynski K, Clark S, Yuan R, Harrison D, et al. Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress. Antioxid Redox Signal. 2011;15:2083-94 pubmed publisher
Kim S, Han S, Withers D, Gaspal F, Bae J, Baik S, et al. CD117? CD3? CD56? OX40Lhigh cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues. Eur J Immunol. 2011;41:1563-72 pubmed publisher
Esplin B, Shimazu T, Welner R, Garrett K, Nie L, Zhang Q, et al. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J Immunol. 2011;186:5367-75 pubmed publisher
Link A, Hardie D, Favre S, Britschgi M, Adams D, Sixt M, et al. Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans. Am J Pathol. 2011;178:1662-75 pubmed publisher
Mortensen M, Soilleux E, Djordjevic G, Tripp R, Lutteropp M, Sadighi Akha E, et al. The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J Exp Med. 2011;208:455-67 pubmed publisher
Yeo C, Fearon D. T-bet-mediated differentiation of the activated CD8+ T cell. Eur J Immunol. 2011;41:60-6 pubmed publisher
Divekar A, Dubey S, Gangalum P, Singh R. Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu. J Immunol. 2011;186:924-30 pubmed publisher
MacNamara K, Oduro K, Martin O, Jones D, McLaughlin M, Choi K, et al. Infection-induced myelopoiesis during intracellular bacterial infection is critically dependent upon IFN-? signaling. J Immunol. 2011;186:1032-43 pubmed publisher
Åhsberg J, Tsapogas P, Qian H, Zetterblad J, Zandi S, Mansson R, et al. Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells. J Biol Chem. 2010;285:36275-84 pubmed publisher
Ji H, Ehrlich L, Seita J, Murakami P, Doi A, Lindau P, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 2010;467:338-42 pubmed publisher
Mueller S, Langley W, Li G, Garcia Sastre A, Webby R, Ahmed R. Qualitatively different memory CD8+ T cells are generated after lymphocytic choriomeningitis virus and influenza virus infections. J Immunol. 2010;185:2182-90 pubmed publisher
Lin E, Kemball C, Hadley A, Wilson J, Hofstetter A, Pack C, et al. Heterogeneity among viral antigen-specific CD4+ T cells and their de novo recruitment during persistent polyomavirus infection. J Immunol. 2010;185:1692-700 pubmed publisher
Anraku M, Tagawa T, Wu L, Yun Z, Keshavjee S, Zhang L, et al. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma. J Immunol. 2010;185:956-66 pubmed publisher
Obar J, Lefrancois L. Early signals during CD8 T cell priming regulate the generation of central memory cells. J Immunol. 2010;185:263-72 pubmed publisher
Gerlach C, van Heijst J, Swart E, Sie D, Armstrong N, Kerkhoven R, et al. One naive T cell, multiple fates in CD8+ T cell differentiation. J Exp Med. 2010;207:1235-46 pubmed publisher
Kittipatarin C, Tschammer N, Khaled A. The interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to interleukin-7. Immunol Lett. 2010;131:170-81 pubmed publisher
Furmanov K, Elnekave M, Lehmann D, Clausen B, Kotton D, Hovav A. The role of skin-derived dendritic cells in CD8+ T cell priming following immunization with lentivectors. J Immunol. 2010;184:4889-97 pubmed publisher
Bivas Benita M, Bar L, Gillard G, Kaufman D, Simmons N, Hovav A, et al. Efficient generation of mucosal and systemic antigen-specific CD8+ T-cell responses following pulmonary DNA immunization. J Virol. 2010;84:5764-74 pubmed publisher
Fewkes N, Krauss A, Guimond M, Meadors J, Dobre S, Mackall C. Pharmacologic modulation of niche accessibility via tyrosine kinase inhibition enhances marrow and thymic engraftment after hematopoietic stem cell transplantation. Blood. 2010;115:4120-9 pubmed publisher
Hirata Y, Hamanaka S, Onodera M. Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B-cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells. Blood. 2010;115:3930-8 pubmed publisher
Chappaz S, Finke D. The IL-7 signaling pathway regulates lymph node development independent of peripheral lymphocytes. J Immunol. 2010;184:3562-9 pubmed publisher
Welner R, Esplin B, Garrett K, Pelayo R, Luche H, Fehling H, et al. Asynchronous RAG-1 expression during B lymphopoiesis. J Immunol. 2009;183:7768-77 pubmed publisher
Zlotoff D, Sambandam A, Logan T, Bell J, Schwarz B, Bhandoola A. CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus. Blood. 2010;115:1897-905 pubmed publisher
Onai N, Manz M, Schmid M. Isolation of common dendritic cell progenitors (CDP) from mouse bone marrow. Methods Mol Biol. 2010;595:195-203 pubmed publisher
Mueller S, Langley W, Carnero E, Garcia Sastre A, Ahmed R. Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses. J Virol. 2010;84:1847-55 pubmed publisher
Rai D, Pham N, Harty J, Badovinac V. Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts. J Immunol. 2009;183:7672-81 pubmed publisher
MacKenzie D, Seroogy C. Sustained expression of GRAIL during hematopoiesis results in dysregulated differentiation. Acta Haematol. 2009;122:230-7 pubmed publisher
Smith E, von Vietinghoff S, Stark M, Zarbock A, Sanders J, Duley A, et al. T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo. J Immunol. 2009;183:5685-93 pubmed publisher
Carlens J, Wahl B, Ballmaier M, Bulfone Paus S, Forster R, Pabst O. Common gamma-chain-dependent signals confer selective survival of eosinophils in the murine small intestine. J Immunol. 2009;183:5600-7 pubmed publisher
Nemoto Y, Kanai T, Kameyama K, Shinohara T, Sakamoto N, Totsuka T, et al. Long-lived colitogenic CD4+ memory T cells residing outside the intestine participate in the perpetuation of chronic colitis. J Immunol. 2009;183:5059-68 pubmed publisher
Withers D, Jaensson E, Gaspal F, McConnell F, Eksteen B, Anderson G, et al. The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals. J Immunol. 2009;183:5079-84 pubmed publisher
Cui Y, Zhang H, Meadors J, Poon R, Guimond M, Mackall C. Harnessing the physiology of lymphopenia to support adoptive immunotherapy in lymphoreplete hosts. Blood. 2009;114:3831-40 pubmed publisher
de Vries V, Wasiuk A, Bennett K, Benson M, Elgueta R, Waldschmidt T, et al. Mast cell degranulation breaks peripheral tolerance. Am J Transplant. 2009;9:2270-80 pubmed publisher
Pham N, Badovinac V, Harty J. A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation. J Immunol. 2009;183:2337-48 pubmed publisher
Doisne J, Bartholin L, Yan K, Garcia C, Duarte N, Le Luduec J, et al. iNKT cell development is orchestrated by different branches of TGF-beta signaling. J Exp Med. 2009;206:1365-78 pubmed publisher
Kutlesa S, Zayas J, Valle A, Levy R, Jurecic R. T-cell differentiation of multipotent hematopoietic cell line EML in the OP9-DL1 coculture system. Exp Hematol. 2009;37:909-23 pubmed publisher
Cridland S, Keys J, Papathanasiou P, Perkins A. Indian hedgehog supports definitive erythropoiesis. Blood Cells Mol Dis. 2009;43:149-55 pubmed publisher
Wirth T, Badovinac V, Zhao L, DAILEY M, Harty J. Differentiation of central memory CD8 T cells is independent of CD62L-mediated trafficking to lymph nodes. J Immunol. 2009;182:6195-206 pubmed publisher
Colombetti S, Lévy F, Chapatte L. IL-7 adjuvant treatment enhances long-term tumor-antigen-specific CD8+ T-cell responses after immunization with recombinant lentivector. Blood. 2009;113:6629-37 pubmed publisher
Vondenhoff M, Greuter M, Goverse G, Elewaut D, Dewint P, Ware C, et al. LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009;182:5439-45 pubmed publisher
Esplin B, Welner R, Zhang Q, BORGHESI L, Kincade P. A differentiation pathway for B1 cells in adult bone marrow. Proc Natl Acad Sci U S A. 2009;106:5773-8 pubmed publisher
Archambaud C, Sansoni A, Mingueneau M, Devilard E, Delsol G, Malissen B, et al. STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells. J Immunol. 2009;182:2680-9 pubmed publisher
Kastenmuller W, Gasteiger G, Stross L, Busch D, Drexler I. Cutting edge: mucosal application of a lyophilized viral vector vaccine confers systemic and protective immunity toward intracellular pathogens. J Immunol. 2009;182:2573-7 pubmed publisher
Maillard I, Chen Y, Friedman A, Yang Y, Tubbs A, Shestova O, et al. Menin regulates the function of hematopoietic stem cells and lymphoid progenitors. Blood. 2009;113:1661-9 pubmed publisher
French J, Roark C, Born W, O Brien R. Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin. J Immunol. 2009;182:1892-900 pubmed publisher
Wirth T, Pham N, Harty J, Badovinac V. High initial frequency of TCR-transgenic CD8 T cells alters inflammation and pathogen clearance without affecting memory T cell function. Mol Immunol. 2009;47:71-8 pubmed publisher
McGeachy M, Chen Y, Tato C, Laurence A, Joyce Shaikh B, Blumenschein W, et al. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol. 2009;10:314-24 pubmed publisher
Cooper M, Elliott J, Keyel P, Yang L, Carrero J, Yokoyama W. Cytokine-induced memory-like natural killer cells. Proc Natl Acad Sci U S A. 2009;106:1915-9 pubmed publisher
Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger E, et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol. 2009;182:259-73 pubmed
Leignadier J, Hardy M, Cloutier M, Rooney J, Labrecque N. Memory T-lymphocyte survival does not require T-cell receptor expression. Proc Natl Acad Sci U S A. 2008;105:20440-5 pubmed publisher
Sheridan B, Cherpes T, Urban J, Kalinski P, Hendricks R. Reevaluating the CD8 T-cell response to herpes simplex virus type 1: involvement of CD8 T cells reactive to subdominant epitopes. J Virol. 2009;83:2237-45 pubmed publisher
Vondenhoff M, van de Pavert S, Dillard M, Greuter M, Goverse G, Oliver G, et al. Lymph sacs are not required for the initiation of lymph node formation. Development. 2009;136:29-34 pubmed publisher
Kraus Z, Haring J, Bishop G. TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection. J Immunol. 2008;181:7800-9 pubmed
Fujii T, Tomita T, Kanai T, Nemoto Y, Totsuka T, Sakamoto N, et al. FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow. Eur J Immunol. 2008;38:3290-303 pubmed publisher
Adoro S, Erman B, Sarafova S, Van Laethem F, Park J, Feigenbaum L, et al. Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic. J Immunol. 2008;181:6975-83 pubmed
Dengler H, Baracho G, Omori S, Bruckner S, Arden K, Castrillon D, et al. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol. 2008;9:1388-98 pubmed publisher
Tang C, Yamada H, Shibata K, Muta H, Wajjwalku W, Podack E, et al. A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection. J Immunol. 2008;181:6316-27 pubmed
Richards J, McNally B, Fang X, Caligiuri M, Zheng P, Liu Y. Tumor growth decreases NK and B cells as well as common lymphoid progenitor. PLoS ONE. 2008;3:e3180 pubmed publisher
Kaufman D, Liu J, Carville A, Mansfield K, Havenga M, Goudsmit J, et al. Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination. J Immunol. 2008;181:4188-98 pubmed
Liston A, Lu L, O Carroll D, Tarakhovsky A, Rudensky A. Dicer-dependent microRNA pathway safeguards regulatory T cell function. J Exp Med. 2008;205:1993-2004 pubmed publisher
Zhou X, Jeker L, Fife B, Zhu S, Anderson M, McManus M, et al. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med. 2008;205:1983-91 pubmed publisher
Rubinstein M, Lind N, Purton J, Filippou P, Best J, McGhee P, et al. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 2008;112:3704-12 pubmed publisher
Tomita T, Kanai T, Nemoto Y, Fujii T, Nozaki K, Okamoto R, et al. Colitogenic CD4+ effector-memory T cells actively recirculate in chronic colitic mice. Inflamm Bowel Dis. 2008;14:1630-40 pubmed publisher
Tsuji M, Suzuki K, Kitamura H, Maruya M, Kinoshita K, Ivanov I, et al. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity. 2008;29:261-71 pubmed publisher
Brinkman C, Sheasley O neill S, Ferguson A, Engelhard V. Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics. J Immunol. 2008;181:1814-24 pubmed
Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, et al. Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis. Inflamm Bowel Dis. 2008;14:1491-503 pubmed publisher
Lee S, Park Y, So T, Kwon B, Cheroutre H, Mittler R, et al. Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells. Nat Immunol. 2008;9:917-26 pubmed publisher
Welner R, Pelayo R, Nagai Y, Garrett K, Wuest T, CARR D, et al. Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection. Blood. 2008;112:3753-61 pubmed publisher
Aerts N, Dombrecht E, Ebo D, Bridts C, Stevens W, De Clerck L. Activated T cells complicate the identification of regulatory T cells in rheumatoid arthritis. Cell Immunol. 2008;251:109-15 pubmed publisher
Wang H, Peters T, Sindrilaru A, Kess D, Oreshkova T, Yu X, et al. TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. J Clin Invest. 2008;118:2629-39 pubmed publisher
Ramsey C, Rubinstein M, Kim D, Cho J, Sprent J, Surh C. The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15. J Immunol. 2008;180:5320-6 pubmed
Arinobu Y, Mizuno S, Chong Y, Shigematsu H, Iino T, Iwasaki H, et al. Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell. 2007;1:416-27 pubmed publisher
Hernandez M, Shen L, Rock K. CD40 on APCs is needed for optimal programming, maintenance, and recall of CD8+ T cell memory even in the absence of CD4+ T cell help. J Immunol. 2008;180:4382-90 pubmed
White A, Withers D, Parnell S, Scott H, Finke D, Lane P, et al. Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input. Eur J Immunol. 2008;38:942-7 pubmed publisher
Desanti G, Cumano A, Golub R. Identification of CD4int progenitors in mouse fetal spleen, a source of resident lymphoid cells. J Leukoc Biol. 2008;83:1145-54 pubmed publisher
Singh P, Yao Y, Weliver A, Broxmeyer H, Hong S, Chang C. Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow. Stem Cells. 2008;26:1009-16 pubmed publisher
Sridhar S, Reyes Sandoval A, Draper S, Moore A, Gilbert S, Gao G, et al. Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. J Virol. 2008;82:3822-33 pubmed publisher
Löhning M, Hegazy A, Pinschewer D, Busse D, Lang K, Hofer T, et al. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. J Exp Med. 2008;205:53-61 pubmed publisher
Carreras E, Turner S, Paharkova Vatchkova V, Mao A, Dascher C, Kovats S. Estradiol acts directly on bone marrow myeloid progenitors to differentially regulate GM-CSF or Flt3 ligand-mediated dendritic cell differentiation. J Immunol. 2008;180:727-38 pubmed
Pongubala J, Northrup D, Lancki D, Medina K, Treiber T, Bertolino E, et al. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol. 2008;9:203-15 pubmed publisher
Hovav A, Panas M, Rahman S, Sircar P, Gillard G, Cayabyab M, et al. Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. J Immunol. 2007;179:6725-33 pubmed
Norris H, Martin A, Lybarger L, Andersen H, Chervenak D, Chervenak R. TCRbeta enhancer activation in early and late lymphoid progenitors. Cell Immunol. 2007;247:59-71 pubmed
Withers D, Kim M, Bekiaris V, Rossi S, Jenkinson W, Gaspal F, et al. The role of lymphoid tissue inducer cells in splenic white pulp development. Eur J Immunol. 2007;37:3240-5 pubmed
Menon S, Chi H, Zhang H, Deng X, Flavell R, Wei N. COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. Nat Immunol. 2007;8:1236-45 pubmed
Liu S, Lizee G, Lou Y, Liu C, Overwijk W, Wang G, et al. IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells. Int Immunol. 2007;19:1213-21 pubmed
Hovav A, Panas M, Osuna C, Cayabyab M, Autissier P, Letvin N. The impact of a boosting immunogen on the differentiation of secondary memory CD8+ T cells. J Virol. 2007;81:12793-802 pubmed
Kohara H, Omatsu Y, Sugiyama T, Noda M, Fujii N, Nagasawa T. Development of plasmacytoid dendritic cells in bone marrow stromal cell niches requires CXCL12-CXCR4 chemokine signaling. Blood. 2007;110:4153-60 pubmed
McKinstry K, Golech S, Lee W, Huston G, Weng N, Swain S. Rapid default transition of CD4 T cell effectors to functional memory cells. J Exp Med. 2007;204:2199-211 pubmed
Fernandez I, Zeiser R, Karsunky H, Kambham N, Beilhack A, Soderstrom K, et al. CD101 surface expression discriminates potency among murine FoxP3+ regulatory T cells. J Immunol. 2007;179:2808-14 pubmed
Wang X, Uto T, Akagi T, Akashi M, Baba M. Induction of potent CD8+ T-cell responses by novel biodegradable nanoparticles carrying human immunodeficiency virus type 1 gp120. J Virol. 2007;81:10009-16 pubmed
Cush S, Anderson K, Ravneberg D, Weslow Schmidt J, Flano E. Memory generation and maintenance of CD8+ T cell function during viral persistence. J Immunol. 2007;179:141-53 pubmed
Yu Q, Xu M, Sen J. Beta-catenin expression enhances IL-7 receptor signaling in thymocytes during positive selection. J Immunol. 2007;179:126-31 pubmed
Badovinac V, Harty J. Manipulating the rate of memory CD8+ T cell generation after acute infection. J Immunol. 2007;179:53-63 pubmed
Meier D, Bornmann C, Chappaz S, Schmutz S, Otten L, Ceredig R, et al. Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. Immunity. 2007;26:643-54 pubmed
Rossi S, Kim M, Leibbrandt A, Parnell S, Jenkinson W, Glanville S, et al. RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J Exp Med. 2007;204:1267-72 pubmed
Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, et al. MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML. Blood. 2007;110:1639-47 pubmed
Stewart C, Walzer T, Robbins S, Malissen B, Vivier E, Prinz I. Germ-line and rearranged Tcrd transcription distinguish bona fide NK cells and NK-like gammadelta T cells. Eur J Immunol. 2007;37:1442-52 pubmed
Hurchla M, Sedy J, Murphy K. Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation. J Immunol. 2007;178:6073-82 pubmed
Astrakhan A, Omori M, Nguyen T, Becker Herman S, Iseki M, Aye T, et al. Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development. Nat Immunol. 2007;8:522-31 pubmed
Fuxa M, Busslinger M. Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function. J Immunol. 2007;178:3031-7 pubmed
Tabatabaei Zavareh N, Vlasova A, Greenwood C, Takei F. Characterization of developmental pathway of natural killer cells from embryonic stem cells in vitro. PLoS ONE. 2007;2:e232 pubmed
Arrode G, Hegde R, Mani A, Jin Y, Chebloune Y, Narayan O. Phenotypic and functional analysis of immune CD8+ T cell responses induced by a single injection of a HIV DNA vaccine in mice. J Immunol. 2007;178:2318-27 pubmed
Piao J, Yoshida H, Yeh W, Doi T, Xue X, Yagita H, et al. TNF receptor-associated factor 2-dependent canonical pathway is crucial for the development of Peyer's patches. J Immunol. 2007;178:2272-7 pubmed
Rossi S, Jeker L, Ueno T, Kuse S, Keller M, Zuklys S, et al. Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells. Blood. 2007;109:3803-11 pubmed
Krieg C, Boyman O, Fu Y, Kaye J. B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation. Nat Immunol. 2007;8:162-71 pubmed
Sheridan B, Khanna K, Frank G, Hendricks R. Latent virus influences the generation and maintenance of CD8+ T cell memory. J Immunol. 2006;177:8356-64 pubmed
Shklovskaya E, Fazekas de St Groth B. Severely impaired clonal deletion of CD4+ T cells in low-dose irradiated mice: role of T cell antigen receptor and IL-7 receptor signals. J Immunol. 2006;177:8320-30 pubmed
Iwasaki H, Mizuno S, Arinobu Y, Ozawa H, Mori Y, Shigematsu H, et al. The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev. 2006;20:3010-21 pubmed
Hovav A, Cayabyab M, Panas M, Santra S, Greenland J, Geiben R, et al. Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis. J Virol. 2007;81:74-83 pubmed
Haring J, Harty J. Aberrant contraction of antigen-specific CD4 T cells after infection in the absence of gamma interferon or its receptor. Infect Immun. 2006;74:6252-63 pubmed
Bahjat K, Liu W, Lemmens E, Schoenberger S, Portnoy D, Dubensky T, et al. Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infect Immun. 2006;74:6387-97 pubmed
Coles M, Veiga Fernandes H, Foster K, Norton T, Pagakis S, Seddon B, et al. Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes. Proc Natl Acad Sci U S A. 2006;103:13457-62 pubmed
Priatel J, Chen X, Dhanji S, Abraham N, Teh H. RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development. J Immunol. 2006;177:1470-80 pubmed
Krueger A, Garbe A, von Boehmer H. Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med. 2006;203:1977-84 pubmed
Chou W, Levy D, Lee C. STAT3 positively regulates an early step in B-cell development. Blood. 2006;108:3005-11 pubmed
Badovinac V, Messingham K, Griffith T, Harty J. TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells. J Immunol. 2006;177:999-1006 pubmed
Moulton V, Bushar N, Leeser D, Patke D, Farber D. Divergent generation of heterogeneous memory CD4 T cells. J Immunol. 2006;177:869-76 pubmed
Dhanji S, Chow M, Teh H. Self-antigen maintains the innate antibacterial function of self-specific CD8 T cells in vivo. J Immunol. 2006;177:138-46 pubmed
Bagaeva L, Rao P, Powers J, Segal B. CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis. J Immunol. 2006;176:7676-85 pubmed
Leithäuser F, Meinhardt Krajina T, Fink K, Wotschke B, Moller P, Reimann J. Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Am J Pathol. 2006;168:1898-909 pubmed
Ceredig R, Rauch M, Balciunaite G, Rolink A. Increasing Flt3L availability alters composition of a novel bone marrow lymphoid progenitor compartment. Blood. 2006;108:1216-22 pubmed
Dumon S, Heath V, Tomlinson M, Gottgens B, Frampton J. Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6. Exp Hematol. 2006;34:654-63 pubmed
Yang T, Millar J, Groves T, Grinshtein N, Parsons R, Takenaka S, et al. The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity. J Immunol. 2006;176:200-10 pubmed
Marquez M, Ellmeier W, Sanchez Guajardo V, Freitas A, Acuto O, Di Bartolo V. CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens. J Immunol. 2005;175:7388-97 pubmed
Masuda K, Kubagawa H, Ikawa T, Chen C, Kakugawa K, Hattori M, et al. Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors. EMBO J. 2005;24:4052-60 pubmed
Lu M, Tayu R, Ikawa T, Masuda K, Matsumoto I, Mugishima H, et al. The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors. J Immunol. 2005;175:5848-56 pubmed
Zhong W, Reinherz E. CD8 alpha alpha homodimer expression and role in CD8 T cell memory generation during influenza virus A infection in mice. Eur J Immunol. 2005;35:3103-10 pubmed
French J, Roark C, Born W, O Brien R. {gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells. Proc Natl Acad Sci U S A. 2005;102:14741-6 pubmed
Lacombe M, Hardy M, Rooney J, Labrecque N. IL-7 receptor expression levels do not identify CD8+ memory T lymphocyte precursors following peptide immunization. J Immunol. 2005;175:4400-7 pubmed
Kuhl C, Atzberger A, Iborra F, Nieswandt B, Porcher C, Vyas P. GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1. Mol Cell Biol. 2005;25:8592-606 pubmed
Tussiwand R, Onai N, Mazzucchelli L, Manz M. Inhibition of natural type I IFN-producing and dendritic cell development by a small molecule receptor tyrosine kinase inhibitor with Flt3 affinity. J Immunol. 2005;175:3674-80 pubmed
Lawrence H, Christensen J, Fong S, Hu Y, Weissman I, Sauvageau G, et al. Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood. 2005;106:3988-94 pubmed
Harfst E, Andersson J, Grawunder U, Ceredig R, Rolink A. Homeostatic and functional analysis of mature B cells in lambda5-deficient mice. Immunol Lett. 2005;101:173-84 pubmed
Fujimura S, Xing Y, Takeya M, Yamashita Y, Ohshima K, Kuwahara K, et al. Increased expression of germinal center-associated nuclear protein RNA-primase is associated with lymphomagenesis. Cancer Res. 2005;65:5925-34 pubmed
Iwasaki H, Somoza C, Shigematsu H, Duprez E, Iwasaki Arai J, Mizuno S, et al. Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood. 2005;106:1590-600 pubmed
Erlandsson L, Licence S, Gaspal F, Lane P, Corcoran A, Martensson I. Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. Eur J Immunol. 2005;35:1969-76 pubmed
Min B, Yamane H, Hu Li J, Paul W. Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms. J Immunol. 2005;174:6039-44 pubmed
Harman B, Jenkinson W, Parnell S, Rossi S, Jenkinson E, Anderson G. T/B lineage choice occurs prior to intrathymic Notch signaling. Blood. 2005;106:886-92 pubmed
Masuda K, Itoi M, Amagai T, Minato N, Katsura Y, Kawamoto H. Thymic anlage is colonized by progenitors restricted to T, NK, and dendritic cell lineages. J Immunol. 2005;174:2525-32 pubmed
Sanchez Guajardo V, Borghans J, Marquez M, Garcia S, Freitas A. Different competitive capacities of Stat4- and Stat6-deficient CD4+ T cells during lymphophenia-driven proliferation. J Immunol. 2005;174:1178-87 pubmed
Arber C, BitMansour A, Sparer T, Higgins J, Mocarski E, Weissman I, et al. Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation. Blood. 2003;102:421-8 pubmed
product information
Product Type :
Antibody
Product Name :
CD127 Monoclonal Antibody (A7R34), PE, eBioscience™
Catalog # :
12-1271-82
Quantity :
100 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Mouse
Clone :
A7R34
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. CD127 consists of an alpha chain and a gamma chain. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells. The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA