CD123 Monoclonal Antibody (6H6), PE, eBioscience™ | Invitrogen 12-1239-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD123 Monoclonal Antibody (6H6), PE, eBioscience™

catalog :

12-1239-42

quantity :

100 Tests

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

6H6

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig s4g	Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
flow cytometry; human; fig 1e	Jobin C, Cloutier M, Simard C, NÃ©ron S. Heterogeneity of in vitro-cultured CD34+ cells isolated from peripheral blood. Cytotherapy. 2015;17:1472-84 pubmed publisher
flow cytometry; human	Longman R, Diehl G, Victorio D, Huh J, Galan C, Miraldi E, et al. CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014;211:1571-83 pubmed publisher
	Braciak T, Roskopf C, Wildenhain S, Fenn N, Schiller C, Schubert I, et al. Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cells. Oncoimmunology. 2018;7:e1472195 pubmed publisher
	Bastian O, Croes M, Alblas J, Koenderman L, Leenen L, Blokhuis T. Neutrophils Inhibit Synthesis of Mineralized Extracellular Matrix by Human Bone Marrow-Derived Stromal Cells In Vitro. Front Immunol. 2018;9:945 pubmed publisher
	Chen J, Wei H, Cheng J, Xie B, Wang B, Yi J, et al. Characteristics of doxorubicin-selected multidrug-resistant human leukemia HL-60 cells with tolerance to arsenic trioxide and contribution of leukemia stem cells. Oncol Lett. 2018;15:1255-1262 pubmed publisher
	Mian S, Rouault Pierre K, Smith A, Seidl T, Pizzitola I, Kizilors A, et al. SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment. Nat Commun. 2015;6:10004 pubmed publisher
	PartlovÃ¡ S, BouÄek J, KloudovÃ¡ K, LukeÅ¡ovÃ¡ E, ZÃ¡brodskÃ½ M, Grega M, et al. Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma. Oncoimmunology. 2015;4:e965570 pubmed
	Accomando W, Wiencke J, Houseman E, Nelson H, Kelsey K. Quantitative reconstruction of leukocyte subsets using DNA methylation. Genome Biol. 2014;15:R50 pubmed publisher
	Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014;10:e1003885 pubmed publisher
	Compte N, Zouaoui Boudjeltia K, Vanhaeverbeek M, De Breucker S, Tassignon J, Trelcat A, et al. Frailty in old age is associated with decreased interleukin-12/23 production in response to toll-like receptor ligation. PLoS ONE. 2013;8:e65325 pubmed publisher
	Ten Berge B, Kleinjan A, Muskens F, Hammad H, Hoogsteden H, Hendriks R, et al. Evidence for local dendritic cell activation in pulmonary sarcoidosis. Respir Res. 2012;13:33 pubmed publisher
	Xu W, He B, Chiu A, Chadburn A, Shan M, Buldys M, et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat Immunol. 2007;8:294-303 pubmed
	Peduzzi E, Groeper C, Schütte D, Zajac P, Rondini S, Mensah Quainoo E, et al. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 2007;127:638-45 pubmed
	Assaf C, Gellrich S, Whittaker S, Robson A, Cerroni L, Massone C, et al. CD56-positive haematological neoplasms of the skin: a multicentre study of the Cutaneous Lymphoma Project Group of the European Organisation for Research and Treatment of Cancer. J Clin Pathol. 2007;60:981-9 pubmed
	Jaye D, Geigerman C, Herling M, Eastburn K, Waller E, Jones D. Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+ CD56+ hematodermic neoplasms. Mod Pathol. 2006;19:1555-62 pubmed

product information

Product Type :

Antibody

Product Name :

CD123 Monoclonal Antibody (6H6), PE, eBioscience™

Catalog # :

12-1239-42

Quantity :

100 Tests

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

6H6

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1

more info or order :

Invitrogen product webpage