This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD94 Monoclonal Antibody (DX22), PE, eBioscience
catalog :
12-0949-42
quantity :
100 Tests
price :
US 300.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
DX22

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 11
Reference
Cheent K, Jamil K, Cassidy S, Liu M, Mbiribindi B, Mulder A, et al. Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94. Proc Natl Acad Sci U S A. 2013;110:16981-6 pubmed publisher
Domaica C, Fuertes M, Uriarte I, Girart M, Sardañons J, Comas D, et al. Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development. PLoS ONE. 2012;7:e51677 pubmed publisher
Hazeldine J, Hampson P, Lord J. Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity. Aging Cell. 2012;11:751-9 pubmed publisher
Farag M, Weigand K, Encke J, Momburg F. Activation of natural killer cells by hepatitis C virus particles in vitro. Clin Exp Immunol. 2011;165:352-62 pubmed publisher
Ablamunits V, Henegariu O, Preston Hurlburt P, Herold K. NKG2A is a marker for acquisition of regulatory function by human CD8+ T cells activated with anti-CD3 antibody. Eur J Immunol. 2011;41:1832-42 pubmed publisher
Aldhamen Y, Appledorn D, Seregin S, Liu C, Schuldt N, Godbehere S, et al. Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. J Immunol. 2011;186:722-32 pubmed publisher
van Velzen M, Laman J, Kleinjan A, Poot A, Osterhaus A, Verjans G. Neuron-interacting satellite glial cells in human trigeminal ganglia have an APC phenotype. J Immunol. 2009;183:2456-61 pubmed publisher
Walsh K, Lanier L, Lane T. NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells: evidence for a protective role in virus-induced encephalitis. J Virol. 2008;82:3031-44 pubmed
Taoudi S, Medvinsky A. Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta. Proc Natl Acad Sci U S A. 2007;104:9399-403 pubmed
Ebert L, Meuter S, Moser B. Homing and function of human skin gammadelta T cells and NK cells: relevance for tumor surveillance. J Immunol. 2006;176:4331-6 pubmed
Takeda K, Cretney E, Hayakawa Y, Ota T, Akiba H, Ogasawara K, et al. TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood. 2005;105:2082-9 pubmed
product information
Product Type :
Antibody
Product Name :
CD94 Monoclonal Antibody (DX22), PE, eBioscience
Catalog # :
12-0949-42
Quantity :
100 Tests
Price :
US 300.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Human
Clone :
DX22
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Natural killer (NK) cells, like CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
Cd94; CD94 antigen; CD94 antigen (located within the rat natural killer gene complex); killer cell lectin like receptor D1; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; killer cell lectin-like receptor, subfamily D, member 1; KLRD1; KP43; natural killer cell receptor; natural killer cells antigen CD94; NK cell receptor
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA