product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD80 (B7-1) Monoclonal Antibody (16-10A1), PE, eBioscience™
catalog :
12-0801-83
quantity :
200 µg
price :
US 309.00
clonality :
monoclonal
host :
hamsters
conjugate :
PE
clone name :
16-10A1
reactivity :
human, mouse, dogs, pigs
application :
flow cytometry
more info or order :
citations: 230
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 3a
Wang H, Mo L, Xiao X, An S, Liu X, Ba J, et al. Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model. Sci Rep. 2017;7:43322 pubmed publisher
  • flow cytometry; mouse; 1:100; fig 2
Schachtner H, Weimershaus M, Stache V, Plewa N, Legler D, Höpken U, et al. Loss of Gadkin Affects Dendritic Cell Migration In Vitro. PLoS ONE. 2015;10:e0143883 pubmed publisher
  • flow cytometry; mouse; fig s3
Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed publisher
  • flow cytometry; mouse; fig 2
McDonnell A, Lesterhuis W, Khong A, Nowak A, Lake R, Currie A, et al. Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy. Eur J Immunol. 2015;45:49-59 pubmed publisher
  • flow cytometry; mouse; fig 3
Harimoto H, Shimizu M, Nakagawa Y, Nakatsuka K, Wakabayashi A, Sakamoto C, et al. Inactivation of tumor-specific CD8? CTLs by tumor-infiltrating tolerogenic dendritic cells. Immunol Cell Biol. 2013;91:545-55 pubmed publisher
  • flow cytometry; mouse
Purtha W, Tedder T, Johnson S, Bhattacharya D, Diamond M. Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants. J Exp Med. 2011;208:2599-606 pubmed publisher
  • flow cytometry; mouse; fig 5
  • flow cytometry; human
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Fan Y, Stronsky S, Xu Y, Steffens J, Van Tongeren S, Erwin A, et al. Multilamellar Vaccine Particle Elicits Potent Immune Activation with Protein Antigens and Protects Mice against Ebola Virus Infection. ACS Nano. 2019;13:11087-11096 pubmed publisher
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Wanderley J, Thorpe P, Barcinski M, Soong L. Phosphatidylserine exposure on the surface of Leishmania amazonensis amastigotes modulates in vivo infection and dendritic cell function. Parasite Immunol. 2013;35:109-119 pubmed publisher
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Chu Y, Soberon V, Glockner L, Beyaert R, Massoumi R, Van Loo G, et al. A20 and CYLD do not share significant overlapping functions during B cell development and activation. J Immunol. 2012;189:4437-43 pubmed publisher
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Li G, Smithey M, Rudd B, Nikolich Zugich J. Age-associated alterations in CD8?+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium. Aging Cell. 2012;11:968-77 pubmed publisher
Treviño Villarreal J, Vera Cabrera L, Valero Guillén P, Salinas Carmona M. Nocardia brasiliensis cell wall lipids modulate macrophage and dendritic responses that favor development of experimental actinomycetoma in BALB/c mice. Infect Immun. 2012;80:3587-601 pubmed publisher
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Ribot J, deBarros A, Mancio Silva L, Pamplona A, Silva Santos B. B7-CD28 costimulatory signals control the survival and proliferation of murine and human ?? T cells via IL-2 production. J Immunol. 2012;189:1202-8 pubmed publisher
Zhu X, Pan Y, Li Y, Cui L, Cao Y. Supplement of L-Arg improves protective immunity during early-stage Plasmodium yoelii 17XL infection. Parasite Immunol. 2012;34:412-20 pubmed publisher
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Köhler T, Reizis B, Johnson R, Weighardt H, Forster I. Influence of hypoxia-inducible factor 1? on dendritic cell differentiation and migration. Eur J Immunol. 2012;42:1226-36 pubmed publisher
Jounai K, Ikado K, Sugimura T, Ano Y, Braun J, Fujiwara D. Spherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cells. PLoS ONE. 2012;7:e32588 pubmed publisher
Iwata Y, Boström E, Menke J, Rabacal W, Morel L, Wada T, et al. Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice. J Immunol. 2012;188:4568-80 pubmed publisher
Rudulier C, Kroeger D, Bretscher P. The activation, by antigen, of naïve TCR transgenic CD4 T cells cultured at physiological, rather than artificially high, frequencies more accurately reflects the in vivo activation of normal numbers of naïve CD4(+) T cells. Cell Immunol. 2012;274:115-20 pubmed publisher
Wang Z, Sokolovska A, Seymour R, Sundberg J, HogenEsch H. SHARPIN is essential for cytokine production, NF-?B signaling, and induction of Th1 differentiation by dendritic cells. PLoS ONE. 2012;7:e31809 pubmed publisher
Gu P, Gao J, D Souza C, Kowalczyk A, Chou K, Zhang L. Trogocytosis of CD80 and CD86 by induced regulatory T cells. Cell Mol Immunol. 2012;9:136-46 pubmed publisher
Nouri Shirazi M, Guinet E. Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination. J Immunol. 2012;188:2359-70 pubmed publisher
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Rose S, Misharin A, Perlman H. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A. 2012;81:343-50 pubmed publisher
Ioannou M, Alissafi T, Lazaridis I, Deraos G, Matsoukas J, Gravanis A, et al. Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease. J Immunol. 2012;188:1136-46 pubmed publisher
Gong H, He L, Li X, Wang Y, Li Y, Huang J, et al. Effective antitumor immunity against murine gliomas using dendritic cells transduced with hTERTC27 recombinant adenovirus. Oncol Rep. 2012;27:1163-9 pubmed publisher
Jang E, Cho M, Oh H, Youn J. Deficiency of foxp3 regulatory T cells exacerbates autoimmune arthritis by altering the synovial proportions of CD4 T cells and dendritic cells. Immune Netw. 2011;11:299-306 pubmed publisher
Boué J, Blanpied C, Djata Cabral M, Pelletier L, Vergnolle N, Dietrich G. Immune conditions associated with CD4+ T effector-induced opioid release and analgesia. Pain. 2012;153:485-93 pubmed publisher
Vaknin I, Kunis G, Miller O, Butovsky O, Bukshpan S, Beers D, et al. Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis. PLoS ONE. 2011;6:e26921 pubmed publisher
Haas K. Programmed cell death 1 suppresses B-1b cell expansion and long-lived IgG production in response to T cell-independent type 2 antigens. J Immunol. 2011;187:5183-95 pubmed publisher
Hinton R, Papathanasiou P, O Neill H. Distinct In Vitro Myelopoiesis is Dependent on the Self-Renewal of Hematopoietic Progenitors. Scand J Immunol. 2012;75:168-75 pubmed publisher
Morgado P, Ong Y, Boothroyd J, Lodoen M. Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun. 2011;79:4401-12 pubmed publisher
Schwarz S, Wong J, Bornemann J, Hodenius M, Himmelreich U, Richtering W, et al. Polyelectrolyte coating of iron oxide nanoparticles for MRI-based cell tracking. Nanomedicine. 2012;8:682-91 pubmed publisher
Strong B, Unanue E. Presentation of type B peptide-MHC complexes from hen egg white lysozyme by TLR ligands and type I IFNs independent of H2-DM regulation. J Immunol. 2011;187:2193-201 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
CD80 (B7-1) Monoclonal Antibody (16-10A1), PE, eBioscience™
Catalog # :
12-0801-83
Quantity :
200 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Armenian Hamster
Reactivity :
Canine, Mouse, Porcine
Applications :
Flow Cytometry: 0.06 µg/test
Species :
Canine, Mouse, Porcine
Clone :
16-10A1
Isotype :
IgG
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.06 µg/test
Aliases :
Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA