CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), PE, eBioscience™ | Invitrogen 12-0719-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), PE, eBioscience™

catalog :

12-0719-42

quantity :

100 Tests

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

OKT9 (OKT-9)

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 7a	Khajuria R, Munschauer M, Ulirsch J, Fiorini C, Ludwig L, McFarland S, et al. Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell. 2018;173:90-103.e19 pubmed publisher
flow cytometry; human	Badarau A, Rouha H, Malafa S, Logan D, HÃ¥kansson M, Stulik L, et al. Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH. J Biol Chem. 2015;290:142-56 pubmed publisher
	Nandakumar S, McFarland S, Mateyka L, Lareau C, Ulirsch J, Ludwig L, et al. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. elife. 2019;8: pubmed publisher
	Wu Y, Xu J, Chen J, Zou M, Rusidanmu A, Yang R. Blocking transferrin receptor inhibits the growth of lung adenocarcinoma cells in vitro. Thorac Cancer. 2018;9:253-261 pubmed publisher
	Huang N, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, et al. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nat Commun. 2017;8:423 pubmed publisher
	Amaral A, Andrade J, Foxall R, Matoso P, Matos A, Soares R, et al. miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication. EMBO J. 2017;36:346-360 pubmed publisher
	Jackson M, Ma R, Taylor A, Axton R, Easterbrook J, Kydonaki M, et al. Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells. Stem Cells Transl Med. 2016;5:981-90 pubmed publisher
	Giani F, Fiorini C, Wakabayashi A, Ludwig L, Salem R, Jobaliya C, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. 2016;18:73-78 pubmed publisher
	Prodinger J, Loacker L, Schmidt R, Ratzinger F, Greiner G, Witzeneder N, et al. The tryptophan metabolite picolinic acid suppresses proliferation and metabolic activity of CD4+ T cells and inhibits c-Myc activation. J Leukoc Biol. 2016;99:583-94 pubmed publisher
	Aparicio Prat E, Arnan C, Sala I, Bosch N, GuigÃ³ R, Johnson R. DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs. BMC Genomics. 2015;16:846 pubmed publisher
	Lee H, Gao X, Barrasa M, Li H, Elmes R, Peters L, et al. PPAR-Î± and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. Nature. 2015;522:474-7 pubmed publisher
	HÃ¤nggi P, Telezhkin V, Kemp P, Schmugge M, Gassmann M, Goede J, et al. Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells. Am J Physiol Cell Physiol. 2015;308:C993-C1007 pubmed publisher
	Shi L, Lin Y, Sierant M, Zhu F, Cui S, Guan Y, et al. Developmental transcriptome analysis of human erythropoiesis. Hum Mol Genet. 2014;23:4528-42 pubmed publisher
	Nellore A, Liu B, Patsoukis N, Boussiotis V, Li L. The cyclin dependent kinase inhibitor (R)-roscovitine mediates selective suppression of alloreactive human T cells but preserves pathogen-specific and leukemia-specific effectors. Clin Immunol. 2014;152:48-57 pubmed publisher
	Ma Y, Wang B, Jiang F, Wang D, Liu H, Yan Y, et al. A feedback loop consisting of microRNA 23a/27a and the ?-like globin suppressors KLF3 and SP1 regulates globin gene expression. Mol Cell Biol. 2013;33:3994-4007 pubmed publisher
	Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
	Sasaki H, Toda T, Furukawa T, Mawatari Y, Takaesu R, Shimizu M, et al. ?-1,6-Fucosyltransferase (FUT8) inhibits hemoglobin production during differentiation of murine and K562 human erythroleukemia cells. J Biol Chem. 2013;288:16839-47 pubmed publisher
	Shi L, Cui S, Engel J, Tanabe O. Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction. Nat Med. 2013;19:291-4 pubmed publisher
	Sjeklocha L, Park C, Wong P, Roney M, Belcher J, Kaufman D, et al. Erythroid-specific expression of ?-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. PLoS ONE. 2011;6:e29110 pubmed publisher
	Dompe N, Rivers C, Li L, Cordes S, Schwickart M, Punnoose E, et al. A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis. Proc Natl Acad Sci U S A. 2011;108:E943-51 pubmed publisher
	Woo A, Kim J, Xu J, Huang H, Cantor A. Role of ZBP-89 in human globin gene regulation and erythroid differentiation. Blood. 2011;118:3684-93 pubmed publisher
	Alvares C, Schenk T, Hulkki S, Min T, Vijayaraghavan G, Yeung J, et al. Tyrosine kinase inhibitor insensitivity of non-cycling CD34+ human acute myeloid leukaemia cells with FMS-like tyrosine kinase 3 mutations. Br J Haematol. 2011;154:457-65 pubmed publisher
	Muranyi A, Dedhar S, Hogge D. Targeting integrin linked kinase and FMS-like tyrosine kinase-3 is cytotoxic to acute myeloid leukemia stem cells but spares normal progenitors. Leuk Res. 2010;34:1358-65 pubmed publisher
	Fukuchi K, Steiniger S, Deryugina E, Liu Y, Lowery C, Gloeckner C, et al. Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Mol Pharm. 2010;7:245-53 pubmed publisher
	Terng H, Gessner R, Fuchs H, Stahl U, Lang C. Human transferrin receptor is active and plasma membrane-targeted in yeast. FEMS Microbiol Lett. 1998;160:61-7 pubmed
	Franco A, Paroli M, Testa U, Benvenuto R, Peschle C, Balsano F, et al. Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes. J Exp Med. 1992;175:1195-205 pubmed

product information

Product Type :

Antibody

Product Name :

CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), PE, eBioscience™

Catalog # :

12-0719-42

Quantity :

100 Tests

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.06 µg)/test

Species :

Human

Clone :

OKT9 (OKT-9)

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.06 µg)/test

Aliases :

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

more info or order :

Invitrogen product webpage