| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; mouse; fig 3
| Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed publisher |
- flow cytometry; mouse; fig 4
| Zhan R, Han Q, Zhang C, Tian Z, Zhang J. Toll-Like receptor 2 (TLR2) and TLR9 play opposing roles in host innate immunity against Salmonella enterica serovar Typhimurium infection. Infect Immun. 2015;83:1641-9 pubmed publisher |
| Barral P, Sanchez Nino M, Van Rooijen N, Cerundolo V, Batista F. The location of splenic NKT cells favours their rapid activation by blood-borne antigen. EMBO J. 2012;31:2378-90 pubmed publisher |
- flow cytometry; mouse; fig 2
| Zou Y, Chen T, Han M, Wang H, Yan W, Song G, et al. Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure. J Immunol. 2010;184:466-75 pubmed publisher |
| Hamdy S, Elamanchili P, Alshamsan A, Molavi O, Satou T, Samuel J. Enhanced antigen-specific primary CD4+ and CD8+ responses by codelivery of ovalbumin and toll-like receptor ligand monophosphoryl lipid A in poly(D,L-lactic-co-glycolic acid) nanoparticles. J Biomed Mater Res A. 2007;81:652-62 pubmed |
| Vanasek T, Nandiwada S, Jenkins M, Mueller D. CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia. J Immunol. 2006;176:5880-9 pubmed |
| Shao B, Wang L, Yu Y, Chen L, Gan N, Huang W. Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation. Exp Ther Med. 2020;20:84 pubmed publisher |
| Flosbach M, Oberle S, Scherer S, Zecha J, von Hoesslin M, Wiede F, et al. PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells. Cell Rep. 2020;32:107957 pubmed publisher |
| Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher |
| Klepsch V, Pommermayr M, Humer D, Brigo N, Hermann Kleiter N, Baier G. Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy. Cell Commun Signal. 2020;18:8 pubmed publisher |
| Chang L, Wang L, Ling N, Peng H, Chen M. Increase in liver γδ T cells with concurrent augmentation of IFN-β production during the early stages of a mouse model of acute experimental hepatitis B virus infection. Exp Ther Med. 2020;19:67-78 pubmed publisher |
| Tong D, Zhang L, Ning F, Xu Y, Hu X, Shi Y. Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival. Protein Cell. 2020;11:108-123 pubmed publisher |
| Anderson C, Reilly E, Lee A, Brossay L. Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection. Cell Rep. 2019;27:537-548.e5 pubmed publisher |
| Hansel C, Erschfeld S, Baues M, Lammers T, Weiskirchen R, Trautwein C, et al. The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis. Front Pharmacol. 2019;10:244 pubmed publisher |
| Andersen T, Huszthy P, Gopalakrishnan R, Jacobsen J, Fauskanger M, Tveita A, et al. Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules. NPJ Vaccines. 2019;4:9 pubmed publisher |
| Funk K, Klein R. CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis. J Neuroinflammation. 2019;16:22 pubmed publisher |
| Yu L, Yang F, Zhang F, Guo D, Li L, Wang X, et al. CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production. Cell Death Dis. 2018;9:905 pubmed publisher |
| Chen E, Brzostek J, Gascoigne N, Rybakin V. Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation. Sci Rep. 2018;8:10046 pubmed publisher |
| Zhang X, Zhu L, Zhou Y, Shi A, Wang H, Han M, et al. Interference with KCTD9 inhibits NK cell activation and ameliorates fulminant liver failure in mice. BMC Immunol. 2018;19:20 pubmed publisher |
| Weng T, Wu H, Li C, Hung Y, Chang Y, Chen Y, et al. Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation. Sci Rep. 2018;8:8216 pubmed publisher |
| Si Y, Wen Y, Kelly S, Chong A, Collier J. Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses. J Control Release. 2018;282:120-130 pubmed publisher |
| Sun C, Lan P, Han Q, Huang M, Zhang Z, Xu G, et al. Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion. Nat Commun. 2018;9:1241 pubmed publisher |
| Annibaldi A, Wicky John S, Vanden Berghe T, Swatek K, Ruan J, Liccardi G, et al. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2. Mol Cell. 2018;69:566-580.e5 pubmed publisher |
| Omodho B, Miao T, Symonds A, Singh R, Li S, Wang P. Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells. Immun Inflamm Dis. 2018;6:221-233 pubmed publisher |
| Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed publisher |
| Ma R, Ji T, Zhang H, Dong W, Chen X, Xu P, et al. A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells. Nat Cell Biol. 2018;20:21-27 pubmed publisher |
| Wang Q, Ning H, Peng H, Wei L, Hou R, Hoft D, et al. Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses. Nat Commun. 2017;8:867 pubmed publisher |
| Chu F, Hu Y, Zhou Y, Guo M, Lu J, Zheng W, et al. MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway. Clin Exp Immunol. 2017;: pubmed publisher |
| Marsden M, Loy B, Wu X, Ramirez C, Schrier A, Murray D, et al. In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication. PLoS Pathog. 2017;13:e1006575 pubmed publisher |
| Li C, Ying W, Huang Z, Brehm T, Morin A, Vella A, et al. IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages. Endocrinology. 2017;158:2837-2847 pubmed publisher |
| Liu H, Zhang Y, Liu Z, Wang P, Mo X, Fu W, et al. LYG1 exerts antitumor function through promoting the activation, proliferation, and function of CD4+ T cells. Oncoimmunology. 2017;6:e1292195 pubmed publisher |
| Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed publisher |
| Ying W, Wollam J, Ofrecio J, Bandyopadhyay G, El Ouarrat D, Lee Y, et al. Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. J Clin Invest. 2017;127:1019-1030 pubmed publisher |
| Zhou Y, Weng X, Dou R, Tan X, Zhang T, Fang J, et al. Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. Acta Pharmacol Sin. 2017;38:201-210 pubmed publisher |
| Allison K, Sajti E, Collier J, Gosselin D, Troutman T, Stone E, et al. Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. elife. 2016;5: pubmed publisher |
| Menendez C, Jinkins J, Carr D. Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency. J Immunol. 2016;197:1262-75 pubmed publisher |
| Chou T, Chuang Y, Hsieh W, Chang P, Liu H, Mo S, et al. Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1? for Th17 suppression. Nat Commun. 2016;7:11904 pubmed publisher |
| Tibbitt C, Falconer J, Stoop J, van Eden W, Robinson J, Hilkens C. Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance. Eur J Immunol. 2016;46:1633-43 pubmed publisher |
| Sebastian M, Lopez Ocasio M, Metidji A, RIEDER S, Shevach E, Thornton A. Helios Controls a Limited Subset of Regulatory T Cell Functions. J Immunol. 2016;196:144-55 pubmed publisher |
| Tan Y, Alkhamees B, Jia D, Li L, Couture J, Figeys D, et al. MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation. Stem Cell Reports. 2015;5:741-52 pubmed publisher |
| Ying W, Tseng A, Chang R, Morin A, Brehm T, Triff K, et al. MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation. J Clin Invest. 2015;125:4149-59 pubmed publisher |
| Rosenheinrich M, Heine W, Schmühl C, Pisano F, Dersch P. Natural Killer Cells Mediate Protection against Yersinia pseudotuberculosis in the Mesenteric Lymph Nodes. PLoS ONE. 2015;10:e0136290 pubmed publisher |
| Major B, Rattazzi L, Brod S, Pilipovic I, Leposavic G, D Acquisto F. Massage-like stroking boosts the immune system in mice. Sci Rep. 2015;5:10913 pubmed publisher |
| Draghiciu O, Nijman H, Hoogeboom B, Meijerhof T, Daemen T. Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication. Oncoimmunology. 2015;4:e989764 pubmed |
| Liu Y, Ji H, Zhang Y, Shen X, Gao F, Nguyen T, et al. Negative CD4 + TIM-3 signaling confers resistance against cold preservation damage in mouse liver transplantation. Am J Transplant. 2015;15:954-964 pubmed publisher |
| Hou H, Liu W, Wu S, Lu Y, Peng J, Zhu Y, et al. Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. PLoS ONE. 2014;9:e110585 pubmed publisher |
| Donohoe D, Holley D, Collins L, Montgomery S, Whitmore A, Hillhouse A, et al. A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner. Cancer Discov. 2014;4:1387-97 pubmed publisher |
| Tousif S, Singh D, Ahmad S, Moodley P, Bhattacharyya M, Van Kaer L, et al. Isoniazid induces apoptosis of activated CD4+ T cells: implications for post-therapy tuberculosis reactivation and reinfection. J Biol Chem. 2014;289:30190-5 pubmed publisher |
| Salmond R, Brownlie R, Morrison V, Zamoyska R. The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals. Nat Immunol. 2014;15:875-883 pubmed publisher |
| Samuchiwal S, Tousif S, Singh D, Kumar A, Ghosh A, Bhalla K, et al. A peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response. BMC Infect Dis. 2014;14:355 pubmed publisher |
| Stober V, Szczesniak C, Childress Q, Heise R, Bortner C, Hollingsworth J, et al. Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression. Am J Physiol Lung Cell Mol Physiol. 2014;306:L1045-55 pubmed publisher |
| Agudo J, Ruzo A, Tung N, Salmon H, Leboeuf M, Hashimoto D, et al. The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids. Nat Immunol. 2014;15:54-62 pubmed publisher |
| Fogel L, Sun M, Geurs T, Carayannopoulos L, French A. Markers of nonselective and specific NK cell activation. J Immunol. 2013;190:6269-76 pubmed publisher |
| Yao C, Hirata T, Soontrapa K, Ma X, Takemori H, Narumiya S. Prostaglandin E? promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase. Nat Commun. 2013;4:1685 pubmed publisher |
| Pan W, Zhou H, Shen Y, Wang Y, Xu Y, Hu Y, et al. Surveillance on the status of immune cells after Echinnococcus granulosus protoscoleces infection in Balb/c mice. PLoS ONE. 2013;8:e59746 pubmed publisher |
| Nolte t Hoen E, van der Vlist E, de Boer Brouwer M, Arkesteijn G, Stoorvogel W, Wauben M. Dynamics of dendritic cell-derived vesicles: high-resolution flow cytometric analysis of extracellular vesicle quantity and quality. J Leukoc Biol. 2013;93:395-402 pubmed publisher |
| Zhang Y, Ji H, Shen X, Cai J, Gao F, Koenig K, et al. Targeting TIM-1 on CD4 T cells depresses macrophage activation and overcomes ischemia-reperfusion injury in mouse orthotopic liver transplantation. Am J Transplant. 2013;13:56-66 pubmed publisher |
| Kaneko T, Saito Y, Kotani T, Okazawa H, Iwamura H, Sato Hashimoto M, et al. Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity. J Immunol. 2012;188:5397-407 pubmed publisher |
| Gu P, Gao J, D Souza C, Kowalczyk A, Chou K, Zhang L. Trogocytosis of CD80 and CD86 by induced regulatory T cells. Cell Mol Immunol. 2012;9:136-46 pubmed publisher |
| Radulovic K, Manta C, Rossini V, Holzmann K, Kestler H, Wegenka U, et al. CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential. J Immunol. 2012;188:2001-13 pubmed publisher |
| Li Z, Zhang C, Zhou Z, Zhang J, Zhang J, Tian Z. Small intestinal intraepithelial lymphocytes expressing CD8 and T cell receptor ?? are involved in bacterial clearance during Salmonella enterica serovar Typhimurium infection. Infect Immun. 2012;80:565-74 pubmed publisher |
| Khong W, Yan B, Yeo H, Tan E, Lee J, Ng J, et al. A non-mouse-adapted enterovirus 71 (EV71) strain exhibits neurotropism, causing neurological manifestations in a novel mouse model of EV71 infection. J Virol. 2012;86:2121-31 pubmed publisher |
| Moro H, Otero D, Tanabe Y, David M. T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival. PLoS ONE. 2011;6:e24972 pubmed publisher |
| Landrigan A, Wong M, Utz P. CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism. J Immunol. 2011;187:3033-43 pubmed publisher |
| Wojno E, Hosken N, Stumhofer J, O Hara A, Mauldin E, Fang Q, et al. A role for IL-27 in limiting T regulatory cell populations. J Immunol. 2011;187:266-73 pubmed publisher |
| Hsiao E, Patterson P. Activation of the maternal immune system induces endocrine changes in the placenta via IL-6. Brain Behav Immun. 2011;25:604-15 pubmed publisher |
| Lee H, Lee H, Kwon Y, Lee J, Kim J, Shin M, et al. Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. J Immunol. 2010;185:6698-705 pubmed publisher |
| Ait Oufella H, Herbin O, Bouaziz J, Binder C, Uyttenhove C, Laurans L, et al. B cell depletion reduces the development of atherosclerosis in mice. J Exp Med. 2010;207:1579-87 pubmed publisher |
| Karamitros D, Kotantaki P, Lygerou Z, Veiga Fernandes H, Pachnis V, Kioussis D, et al. Differential geminin requirement for proliferation of thymocytes and mature T cells. J Immunol. 2010;184:2432-41 pubmed publisher |
| Grabner R, Lotzer K, Döpping S, Hildner M, Radke D, Beer M, et al. Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. J Exp Med. 2009;206:233-48 pubmed publisher |
| Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger E, et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol. 2009;182:259-73 pubmed |
| Ciabattini A, Pettini E, Andersen P, Pozzi G, Medaglini D. Primary activation of antigen-specific naive CD4+ and CD8+ T cells following intranasal vaccination with recombinant bacteria. Infect Immun. 2008;76:5817-25 pubmed publisher |
| Sanabria M, Vargas Inchaustegui D, Xin L, Soong L. Role of natural killer cells in modulating dendritic cell responses to Leishmania amazonensis infection. Infect Immun. 2008;76:5100-9 pubmed publisher |
| Brinkman C, Sheasley O neill S, Ferguson A, Engelhard V. Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics. J Immunol. 2008;181:1814-24 pubmed |
| Molavi O, Ma Z, Hamdy S, Lai R, Lavasanifar A, Samuel J. Synergistic antitumor effects of CpG oligodeoxynucleotide and STAT3 inhibitory agent JSI-124 in a mouse melanoma tumor model. Immunol Cell Biol. 2008;86:506-14 pubmed publisher |
| Menke J, Zeller G, Kikawada E, Means T, Huang X, Lan H, et al. CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease. J Am Soc Nephrol. 2008;19:1177-89 pubmed publisher |
| Wanasen N, Xin L, Soong L. Pathogenic role of B cells and antibodies in murine Leishmania amazonensis infection. Int J Parasitol. 2008;38:417-29 pubmed |
| Xin L, Li Y, Soong L. Role of interleukin-1beta in activating the CD11c(high) CD45RB- dendritic cell subset and priming Leishmania amazonensis-specific CD4+ T cells in vitro and in vivo. Infect Immun. 2007;75:5018-26 pubmed |
| Anis M, Fulton S, Reba S, Harding C, Boom W. Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection. Infect Immun. 2007;75:2260-8 pubmed |
| Ha S, Tsuji M, Suzuki K, Meek B, Yasuda N, Kaisho T, et al. Regulation of B1 cell migration by signals through Toll-like receptors. J Exp Med. 2006;203:2541-50 pubmed |
| D Acquisto F, Merghani A, Lecona E, Rosignoli G, Raza K, Buckley C, et al. Annexin-1 modulates T-cell activation and differentiation. Blood. 2007;109:1095-102 pubmed |
| Bahjat K, Liu W, Lemmens E, Schoenberger S, Portnoy D, Dubensky T, et al. Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infect Immun. 2006;74:6387-97 pubmed |
| Hale J, Boursalian T, Turk G, Fink P. Thymic output in aged mice. Proc Natl Acad Sci U S A. 2006;103:8447-52 pubmed |
| Wang J, Sun R, Wei H, Dong Z, Gao B, Tian Z. Poly I:C prevents T cell-mediated hepatitis via an NK-dependent mechanism. J Hepatol. 2006;44:446-54 pubmed |
| Hsu S, Wu C, Han J, Lai M. Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development. Blood. 2003;101:970-6 pubmed |
| Yu C, Feng M, Shih H, Lai M. Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection. Mol Cell Biol. 2002;22:4556-66 pubmed |
