This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD61 (Integrin beta 3) Monoclonal Antibody (VI-PL2), PE, eBioscience
catalog :
12-0619-42
quantity :
100 Tests
price :
US 303.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
VI-PL2

The same clone is also sold as:
reactivity :
crab eating macaque, human, dogs, rhesus macaque
application :
flow cytometry
citations: 10
Reference
Jiang M, Wu W, Xia Y, Wang X, Liang J. Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps. BMC Immunol. 2023;24:22 pubmed publisher
Kerherv xe9 M, Rosi x144 ska S, Trillet K, Zeinaty A, Feyeux M, Nedellec S, et al. Neuropilin-1 modulates the 3D invasive properties of glioblastoma stem-like cells. Front Cell Dev Biol. 2022;10:981583 pubmed publisher
Garcia Montolio M, Ballaré C, Blanco E, Gutierrez A, Aranda S, Gomez A, et al. Polycomb Factor PHF19 Controls Cell Growth and Differentiation Toward Erythroid Pathway in Chronic Myeloid Leukemia Cells. Front Cell Dev Biol. 2021;9:655201 pubmed publisher
Sato M, Veir J, Shropshire S, Lappin M. Ehrlichia canis in dogs experimentally infected, treated, and then immune suppressed during the acute or subclinical phases. J Vet Intern Med. 2020;34:1214-1221 pubmed publisher
Shropshire S, Olver C, Lappin M. Characteristics of hemostasis during experimental Ehrlichia canis infection. J Vet Intern Med. 2018;32:1334-1342 pubmed publisher
Huang H, Huang Q, Wang F, Milner R, Li L. Cerebral ischemia-induced angiogenesis is dependent on tumor necrosis factor receptor 1-mediated upregulation of α5β1 and αVβ3 integrins. J Neuroinflammation. 2016;13:227 pubmed publisher
Zhang S, Ye J, Zhang Y, Xu X, Liu J, Zhang S, et al. P2Y12 protects platelets from apoptosis via PI3k-dependent Bak/Bax inactivation. J Thromb Haemost. 2013;11:149-60 pubmed publisher
Barrett L, Dai C, Gamberg J, Gallant M, Grant M. Circulating CD14-CD36+ peripheral blood mononuclear cells constitutively produce interleukin-10. J Leukoc Biol. 2007;82:152-60 pubmed
Roberts M, Woods A, Dale T, van der Sluijs P, Norman J. Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins. Mol Cell Biol. 2004;24:1505-15 pubmed
Ciarlet M, Crawford S, Cheng E, Blutt S, Rice D, Bergelson J, et al. VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. J Virol. 2002;76:1109-23 pubmed
product information
Product Type :
Antibody
Product Name :
CD61 (Integrin beta 3) Monoclonal Antibody (VI-PL2), PE, eBioscience
Catalog # :
12-0619-42
Quantity :
100 Tests
Price :
US 303.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Baboon, Canine, Cynomolgus Monkey, Human, Rhesus Monkey
Applications :
Flow Cytometry: 5 uL (0.06 ug)/test
Species :
Baboon, Canine, Cynomolgus Monkey, Human, Rhesus Monkey
Clone :
VI-PL2
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin. CD61 is a 105 kDa glycoprotein that associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, Von Willebrand Factor, vitronectin and thrombospondin. The CD61 protein product is composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. CD61 is found along with the alpha IIb chain in platelets. Like other integrins, CD61 is known to participate in cell adhesion as well as cell-surface mediated signaling. Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.06 ug)/test
Aliases :
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA