product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD54 (ICAM-1) Monoclonal Antibody (HA58), PE, eBioscience™
catalog :
12-0549-42
quantity :
100 Tests
price :
US 309.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
HA58
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 37
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 5a
Lim S, Kim J, Jeon S, Shin M, Kwon J, Kim T, et al. Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients. Front Immunol. 2019;10:496 pubmed publisher
  • flow cytometry; human
Ziblat A, Domaica C, Spallanzani R, Iraolagoitia X, Rossi L, Avila D, et al. IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness. Eur J Immunol. 2015;45:192-202 pubmed publisher
Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
Hough K, Wilson L, Trevor J, Strenkowski J, Maina N, Kim Y, et al. Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics. Sci Rep. 2018;8:10340 pubmed publisher
Lipps C, Klein F, Wahlicht T, Seiffert V, Butueva M, Zauers J, et al. Expansion of functional personalized cells with specific transgene combinations. Nat Commun. 2018;9:994 pubmed publisher
Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
Li C, Liu S, Yan R, Han N, WONG K, Li L. CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer. Theranostics. 2017;7:67-80 pubmed publisher
Faes S, Uldry E, Planche A, Santoro T, Pythoud C, Demartines N, et al. Acidic pH reduces VEGF-mediated endothelial cell responses by downregulation of VEGFR-2; relevance for anti-angiogenic therapies. Oncotarget. 2016;7:86026-86038 pubmed publisher
Merkel S, Andrews A, Lutton E, Mu D, Hudry E, Hyman B, et al. Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells. J Neurochem. 2017;140:216-230 pubmed publisher
Miyabe Y, Miyabe C, Iwai Y, Yokoyama W, Sekine C, Sugimoto K, et al. Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid-lysophosphatidic acid receptor 1 cascade. Arthritis Res Ther. 2014;16:461 pubmed publisher
An N, Andrukhov O, Tang Y, Falkensammer F, Bantleon H, Ouyang X, et al. Effect of nicotine and porphyromonas gingivalis lipopolysaccharide on endothelial cells in vitro. PLoS ONE. 2014;9:e96942 pubmed publisher
Stoler Barak L, Barzilai S, Zauberman A, Alon R. Transendothelial migration of effector T cells across inflamed endothelial barriers does not require heparan sulfate proteoglycans. Int Immunol. 2014;26:315-24 pubmed publisher
Compeer E, Flinsenberg T, Boon L, Hoekstra M, Boes M. Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation. J Biol Chem. 2014;289:520-8 pubmed publisher
Evani S, Prabhu R, Gnanaruban V, Finol E, Ramasubramanian A. Monocytes mediate metastatic breast tumor cell adhesion to endothelium under flow. FASEB J. 2013;27:3017-29 pubmed publisher
Liu S, Li N, Yu X, Xiao X, Cheng K, Hu J, et al. Expression of intercellular adhesion molecule 1 by hepatocellular carcinoma stem cells and circulating tumor cells. Gastroenterology. 2013;144:1031-1041.e10 pubmed publisher
Lo Schiavo V, Robert P, Limozin L, Bongrand P. Quantitative modeling assesses the contribution of bond strengthening, rebinding and force sharing to the avidity of biomolecule interactions. PLoS ONE. 2012;7:e44070 pubmed
Qin Y, Li Y, Liu W, Tian R, Guo Q, Li S, et al. Penicillium marneffei-stimulated dendritic cells enhance HIV-1 trans-infection and promote viral infection by activating primary CD4+ T cells. PLoS ONE. 2011;6:e27609 pubmed publisher
Robert P, Nicolas A, Aranda Espinoza S, Bongrand P, Limozin L. Minimal encounter time and separation determine ligand-receptor binding in cell adhesion. Biophys J. 2011;100:2642-51 pubmed publisher
Charoenphol P, Mocherla S, Bouïs D, Namdee K, Pinsky D, Eniola Adefeso O. Targeting therapeutics to the vascular wall in atherosclerosis--carrier size matters. Atherosclerosis. 2011;217:364-70 pubmed publisher
Uldrick T, Polizzotto M, Aleman K, O Mahony D, Wyvill K, Wang V, et al. High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy. Blood. 2011;117:6977-86 pubmed publisher
Kina K, Masuda H, Nakayama H, Nagatsuka Y, Nabetani T, Hirabayashi Y, et al. The novel neutrophil differentiation marker phosphatidylglucoside mediates neutrophil apoptosis. J Immunol. 2011;186:5323-32 pubmed publisher
Allaeys I, Rusu D, Picard S, Pouliot M, Borgeat P, Poubelle P. Osteoblast retraction induced by adherent neutrophils promotes osteoclast bone resorption: implication for altered bone remodeling in chronic gout. Lab Invest. 2011;91:905-20 pubmed publisher
Kim T, Kim N, Kang H, Kim E, Kim S, Ahn H, et al. FK506 causes cellular and functional defects in human natural killer cells. J Leukoc Biol. 2010;88:1089-97 pubmed publisher
Rydberg C, Mansson A, Uddman R, Riesbeck K, Cardell L. Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas. Immunology. 2009;128:e600-11 pubmed publisher
Wang J, Kwas C, Wu L. Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission. J Virol. 2009;83:4195-204 pubmed publisher
Okumura S, Yuki K, Kobayashi R, Okamura S, Ohmori K, Saito H, et al. Hyperexpression of NOD2 in intestinal mast cells of Crohn's disease patients: preferential expression of inflammatory cell-recruiting molecules via NOD2 in mast cells. Clin Immunol. 2009;130:175-85 pubmed publisher
Noborio Hatano K, Kikuchi J, Takatoku M, Shimizu R, Wada T, Ueda M, et al. Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma. Oncogene. 2009;28:231-42 pubmed publisher
Robert P, Sengupta K, Puech P, Bongrand P, Limozin L. Tuning the formation and rupture of single ligand-receptor bonds by hyaluronan-induced repulsion. Biophys J. 2008;95:3999-4012 pubmed publisher
Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed publisher
Mandron M, Ariès M, Boralevi F, Martin H, Charveron M, Taieb A, et al. Age-related differences in sensitivity of peripheral blood monocytes to lipopolysaccharide and Staphylococcus aureus toxin B in atopic dermatitis. J Invest Dermatol. 2008;128:882-9 pubmed
Nakhaei Nejad M, Hussain A, Zhang Q, Murray A. Endothelial PI 3-kinase activity regulates lymphocyte diapedesis. Am J Physiol Heart Circ Physiol. 2007;293:H3608-16 pubmed
Schierloh P, Yokobori N, Aleman M, Landoni V, Geffner L, Musella R, et al. Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy. Infect Immun. 2007;75:5325-37 pubmed
Yotsui T, Yasuda O, Kawamoto H, Higuchi M, Chihara Y, Umemoto E, et al. Aspirin prevents adhesion of T lymphoblasts to vascular smooth muscle cells. FEBS Lett. 2007;581:427-32 pubmed
Kim J, Choi E, Shin H, Kim C, Hwang S, Kim S, et al. Characterization of monoclonal antibody specific to the Z39Ig protein, a member of immunoglobulin superfamily. Immunol Lett. 2005;99:153-61 pubmed
Kanwar J, Berg R, Yang Y, Kanwar R, Ching L, Sun X, et al. Requirements for ICAM-1 immunogene therapy of lymphoma. Cancer Gene Ther. 2003;10:468-76 pubmed
Bao J, Sato K, Li M, Gao Y, Abid R, Aird W, et al. PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated I kappa B alpha degradation. Am J Physiol Heart Circ Physiol. 2001;281:H2612-8 pubmed
Davis D, Chiu I, Fassett M, Cohen G, Mandelboim O, Strominger J. The human natural killer cell immune synapse. Proc Natl Acad Sci U S A. 1999;96:15062-7 pubmed
product information
Product Type :
Antibody
Product Name :
CD54 (ICAM-1) Monoclonal Antibody (HA58), PE, eBioscience™
Catalog # :
12-0549-42
Quantity :
100 Tests
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.25 µg)/test
Species :
Human
Clone :
HA58
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.25 µg)/test
Aliases :
BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly-47; major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA