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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), PE, eBioscience™
catalog :
12-0541-81
quantity :
50 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
YN1/1.7.4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Kiesel J, Buchwald Z, Aurora R. Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells. J Immunol. 2009;182:5477-87 pubmed publisher
Lalor R, O Neill S. Bovine κ-Casein Fragment Induces Hypo-Responsive M2-Like Macrophage Phenotype. Nutrients. 2019;11: pubmed publisher
Kanitz A, Syed A, Kaji K, Zavolan M. Conserved regulation of RNA processing in somatic cell reprogramming. BMC Genomics. 2019;20:100 pubmed publisher
Cousin C, Oberkampf M, Félix T, Rosenbaum P, Weil R, Fabrega S, et al. Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses. Cell Rep. 2019;26:1242-1257.e7 pubmed publisher
Deloch L, Rückert M, Fietkau R, Frey B, Gaipl U. Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints. Int J Mol Sci. 2018;19: pubmed publisher
Deloch L, Derer A, Hueber A, Herrmann M, Schett G, Wölfelschneider J, et al. Low-Dose Radiotherapy Ameliorates Advanced Arthritis in hTNF-α tg Mice by Particularly Positively Impacting on Bone Metabolism. Front Immunol. 2018;9:1834 pubmed publisher
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed publisher
Gittens B, Bodkin J, Nourshargh S, Perretti M, Cooper D. Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation. J Immunol. 2017;198:4458-4469 pubmed publisher
Zhang D, Chen G, Manwani D, Mortha A, Xu C, Faith J, et al. Neutrophil ageing is regulated by the microbiome. Nature. 2015;525:528-32 pubmed publisher
Chantzoura E, Skylaki S, Menendez S, Kim S, Johnsson A, Linnarsson S, et al. Reprogramming Roadblocks Are System Dependent. Stem Cell Reports. 2015;5:350-64 pubmed publisher
Buschmann K, Poeschl J, Braach N, Hudalla H, Kuss N, Frommhold D. The olive oil-based lipid clinoleic blocks leukocyte recruitment and improves survival during systemic inflammation: a comparative in vivo study of different parenteral lipid emulsions. Mediators Inflamm. 2015;2015:757059 pubmed publisher
Larsen J, Dall M, Antvorskov J, Weile C, Engkilde K, Josefsen K, et al. Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion. Eur J Immunol. 2014;44:3056-67 pubmed publisher
Braach N, Frommhold D, Buschmann K, Pflaum J, Koch L, Hudalla H, et al. RAGE controls activation and anti-inflammatory signalling of protein C. PLoS ONE. 2014;9:e89422 pubmed publisher
Bénézech C, Nayar S, Finney B, Withers D, Lowe K, Desanti G, et al. CLEC-2 is required for development and maintenance of lymph nodes. Blood. 2014;123:3200-7 pubmed publisher
O MALLEY J, Skylaki S, Iwabuchi K, Chantzoura E, Ruetz T, Johnsson A, et al. High-resolution analysis with novel cell-surface markers identifies routes to iPS cells. Nature. 2013;499:88-91 pubmed publisher
Nice T, Deng W, Coscoy L, Raulet D. Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase. J Immunol. 2010;185:5369-76 pubmed publisher
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace W, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity. 2010;33:71-83 pubmed publisher
Bénézech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, et al. Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010;184:4521-30 pubmed publisher
Dace D, Khan A, Stark J, Kelly J, Cross A, Apte R. Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy. PLoS ONE. 2009;4:e7121 pubmed publisher
Zietara N, Łyszkiewicz M, Gekara N, Puchałka J, dos Santos V, Hunt C, et al. Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70. J Immunol. 2009;183:1099-109 pubmed publisher
Zhang H, Rosenberg S, Coffey F, He Y, Manser T, Hardy R, et al. A role for cFLIP in B cell proliferation and stress MAPK regulation. J Immunol. 2009;182:207-15 pubmed
Stefanidakis M, Newton G, Lee W, Parkos C, Luscinskas F. Endothelial CD47 interaction with SIRPgamma is required for human T-cell transendothelial migration under shear flow conditions in vitro. Blood. 2008;112:1280-9 pubmed publisher
White A, Carragher D, Parnell S, Msaki A, Perkins N, Lane P, et al. Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis. Blood. 2007;110:1950-9 pubmed
Imtiyaz H, Rosenberg S, Zhang Y, Rahman Z, Hou Y, Manser T, et al. The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells. J Immunol. 2006;176:6852-61 pubmed
Harman B, Jenkinson W, Parnell S, Rossi S, Jenkinson E, Anderson G. T/B lineage choice occurs prior to intrathymic Notch signaling. Blood. 2005;106:886-92 pubmed
product information
Product Type :
Antibody
Product Name :
CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), PE, eBioscience™
Catalog # :
12-0541-81
Quantity :
50 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 µg/test
Species :
Mouse
Clone :
YN1/1.7.4
Isotype :
IgG2b, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 µg/test
Aliases :
BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly-47; major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA