CD51 (Integrin alpha V) Monoclonal Antibody (RMV-7), PE, eBioscience™ | Invitrogen 12-0512-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD51 (Integrin alpha V) Monoclonal Antibody (RMV-7), PE, eBioscience™

catalog :

12-0512-81

quantity :

50 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

RMV-7

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 41

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200; fig s6a	Kim J, Yang Y, Park K, Ge X, Xu R, Li N, et al. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020;11:2289 pubmed publisher
flow cytometry; mouse; loading ...; fig s1a	Chen Y, Qin X, An Q, Yi J, Feng F, Yin D, et al. Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes. EBioMedicine. 2018;32:31-42 pubmed publisher
flow cytometry; mouse; 1:250; fig st1	Brinkman C, Iwami D, Hritzo M, Xiong Y, Ahmad S, Simon T, et al. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nat Commun. 2016;7:12021 pubmed publisher
flow cytometry; mouse; fig 3	Cordeiro O, Chypre M, Brouard N, Rauber S, Alloush F, Romera Hernandez M, et al. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS ONE. 2016;11:e0151848 pubmed publisher
	Balzano M, De Grandis M, Vu Manh T, Chasson L, Bardin F, Farina A, et al. Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche. Cell Rep. 2019;26:3257-3271.e8 pubmed publisher
	Chaudhury S, O Connor C, Cañete A, Bittencourt Silvestre J, Sarrou E, Prendergast Á, et al. Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. Nat Commun. 2018;9:5280 pubmed publisher
	Maryanovich M, Zahalka A, Pierce H, Pinho S, Nakahara F, Asada N, et al. Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nat Med. 2018;24:782-791 pubmed publisher
	Murray I, González Z, Baily J, Dobie R, Wallace R, MacKinnon A, et al. αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis. Nat Commun. 2017;8:1118 pubmed publisher
	Penton C, Badarinarayana V, Prisco J, Powers E, Pincus M, Allen R, et al. Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion. Skelet Muscle. 2016;6:44 pubmed
	Rux D, Song J, Swinehart I, Pineault K, Schlientz A, Trulik K, et al. Regionally Restricted Hox Function in Adult Bone Marrow Multipotent Mesenchymal Stem/Stromal Cells. Dev Cell. 2016;39:653-666 pubmed publisher
	Lu X, Chen Q, Rong Y, Yang G, Li C, Xu N, et al. LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells. Nat Commun. 2016;7:12719 pubmed publisher
	Loder S, Agarwal S, Sorkin M, Breuler C, Li J, Peterson J, et al. Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification. Ann Surg. 2016;264:1174-1180 pubmed
	Agarwal S, Loder S, Brownley C, Eboda O, Peterson J, Hayano S, et al. BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints. Dev Biol. 2015;400:202-9 pubmed publisher
	Bruns I, Lucas D, Pinho S, Ahmed J, Lambert M, Kunisaki Y, et al. Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nat Med. 2014;20:1315-20 pubmed publisher
	König K, Marth L, Roissant J, Granja T, Jennewein C, Devanathan V, et al. The plexin C1 receptor promotes acute inflammation. Eur J Immunol. 2014;44:2648-58 pubmed publisher
	Mullins C, Schubert J, Schneider B, Linnebacher M, Classen C. Cilengitide response in ultra-low passage glioblastoma cell lines: relation to molecular markers. J Cancer Res Clin Oncol. 2013;139:1425-31 pubmed publisher
	Lucas D, Scheiermann C, Chow A, Kunisaki Y, Bruns I, Barrick C, et al. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nat Med. 2013;19:695-703 pubmed publisher
	Zhang Y, Jones M, McCabe A, Winslow G, Avram D, MacNamara K. MyD88 signaling in CD4 T cells promotes IFN-? production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection. J Immunol. 2013;190:4725-35 pubmed publisher
	Zeng R, Oderup C, Yuan R, Lee M, Habtezion A, Hadeiba H, et al. Retinoic acid regulates the development of a gut-homing precursor for intestinal dendritic cells. Mucosal Immunol. 2013;6:847-56 pubmed publisher
	Sorace A, Saini R, Mahoney M, Hoyt K. Molecular ultrasound imaging using a targeted contrast agent for assessing early tumor response to antiangiogenic therapy. J Ultrasound Med. 2012;31:1543-50 pubmed
	Fekete N, Rojewski M, Furst D, Kreja L, Ignatius A, Dausend J, et al. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS ONE. 2012;7:e43255 pubmed publisher
	Yoshizawa K, Nakajima S, Notake T, Miyagawa S, Hida S, Taki S. IL-15-high-responder developing NK cells bearing Ly49 receptors in IL-15-/- mice. J Immunol. 2011;187:5162-9 pubmed publisher
	Warram J, Sorace A, Saini R, Umphrey H, Zinn K, Hoyt K. A triple-targeted ultrasound contrast agent provides improved localization to tumor vasculature. J Ultrasound Med. 2011;30:921-31 pubmed
	Sprague L, Muccioli M, Pate M, Meles E, McGinty J, Nandigam H, et al. The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells. BMC Immunol. 2011;12:35 pubmed publisher
	Thomas S, Scanlon S, Griewank K, Constantinides M, Savage A, Barr K, et al. PLZF induces an intravascular surveillance program mediated by long-lived LFA-1-ICAM-1 interactions. J Exp Med. 2011;208:1179-88 pubmed publisher
	Uchida Y, Kawai K, Ibusuki A, Kanekura T. Role for E-cadherin as an inhibitory receptor on epidermal gammadelta T cells. J Immunol. 2011;186:6945-54 pubmed publisher
	Choi H, Kim J, Kwon E, Che J, Lee J, Cho S, et al. Establishment of efficacy and safety assessment of human adipose tissue-derived mesenchymal stem cells (hATMSCs) in a nude rat femoral segmental defect model. J Korean Med Sci. 2011;26:482-91 pubmed publisher
	Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam L, Chrzanowska Wodnicka M, et al. Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. J Exp Med. 2010;207:1923-38 pubmed publisher
	Dudeck A, Leist M, Rubant S, Zimmermann A, Dudeck J, Boehncke W, et al. Immature mast cells exhibit rolling and adhesion to endothelial cells and subsequent diapedesis triggered by E- and P-selectin, VCAM-1 and PECAM-1. Exp Dermatol. 2010;19:424-34 pubmed publisher
	Hsu D, Chernyavsky A, Chen H, Yu L, Grando S, Liu F. Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol. 2009;129:573-83 pubmed publisher
	Guo H, Samarakoon A, Vanhaesebroeck B, Malarkannan S. The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. J Exp Med. 2008;205:2419-35 pubmed publisher
	Yakubenko V, Belevych N, Mishchuk D, Schurin A, Lam S, Ugarova T. The role of integrin alpha D beta2 (CD11d/CD18) in monocyte/macrophage migration. Exp Cell Res. 2008;314:2569-78 pubmed publisher
	Nobumoto A, Nagahara K, Oomizu S, Katoh S, Nishi N, Takeshita K, et al. Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices. Glycobiology. 2008;18:735-44 pubmed publisher
	Zhao J, Qi Q, Yang Y, Gu H, Lu N, Liu W, et al. Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid. Eur J Pharmacol. 2008;589:127-31 pubmed publisher
	Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed publisher
	McGowan S, Holmes A, Mecham R, Ritty T. Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration. Am J Respir Cell Mol Biol. 2008;38:435-45 pubmed
	Roy A, Liu X, Pahan K. Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. J Biol Chem. 2007;282:32222-32 pubmed
	Malarkannan S, Regunathan J, Chu H, Kutlesa S, Chen Y, Zeng H, et al. Bcl10 plays a divergent role in NK cell-mediated cytotoxicity and cytokine generation. J Immunol. 2007;179:3752-62 pubmed
	Liu X, Bandyopadhyay B, Bandyopadhyay B, Nakamoto T, Singh B, Liedtke W, et al. A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery. J Biol Chem. 2006;281:15485-95 pubmed
	Richards J, Chang X, Blaser B, Caligiuri M, Zheng P, Liu Y. Tumor growth impedes natural-killer-cell maturation in the bone marrow. Blood. 2006;108:246-52 pubmed
	Robbins S, Tessmer M, Van Kaer L, Brossay L. Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation. Eur J Immunol. 2005;35:757-65 pubmed

product information

Product Type :

Antibody

Product Name :

CD51 (Integrin alpha V) Monoclonal Antibody (RMV-7), PE, eBioscience™

Catalog # :

12-0512-81

Quantity :

50 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test

Species :

Mouse

Clone :

RMV-7

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test

Aliases :

1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen identified by monoclonal antibody L230; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; integrin alpha V; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; integrin subunit alpha V; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; ITGB3; MSK8; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor subunit alpha; VNR; VNRA; VTNR

more info or order :

Invitrogen product webpage