| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; mouse; loading ...; fig 3c
| Bai L, Lyu Y, Shi G, Li K, Huang Y, Ma Y, et al. Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells. Aging (Albany NY). 2020;12:20152-20162 pubmed publisher |
- flow cytometry; mouse; loading ...
| Lissner M, Cumnock K, Davis N, Vilches Moure J, Basak P, Navarrete D, et al. Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury. elife. 2020;9: pubmed publisher |
- flow cytometry; mouse; 1:200; loading ...; fig s2a
| Han C, Kang I, Harten I, Gebe J, Chan C, Omer M, et al. Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity. Cell Rep. 2020;31:107818 pubmed publisher |
- flow cytometry; mouse; fig s2g
| Ho T, Warr M, Adelman E, Lansinger O, Flach J, Verovskaya E, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543:205-210 pubmed publisher |
- flow cytometry; mouse; fig 7
| Pietras E, Mirantes Barbeito C, Fong S, Loeffler D, Kovtonyuk L, Zhang S, et al. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol. 2016;18:607-18 pubmed publisher |
- flow cytometry; mouse; fig 3g
| Varney M, Niederkorn M, Konno H, Matsumura T, Gohda J, Yoshida N, et al. Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling. J Exp Med. 2015;212:1967-85 pubmed publisher |
| Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, et al. TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS Pathog. 2014;10:e1003900 pubmed publisher |
| Li J, Chin C, Ying H, Meydan C, Teater M, Xia M, et al. Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment. Nat Commun. 2024;15:2879 pubmed publisher |
| Little A, Chen P, Vesely M, Khan R, Fiedler J, Garritano J, et al. HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease. JCI Insight. 2023;8: pubmed publisher |
| Chernova I, Song W, Steach H, Hafez O, Al Souz J, Chen P, et al. The ion transporter Na+-K+-ATPase enables pathological B cell survival in the kidney microenvironment of lupus nephritis. Sci Adv. 2023;9:eadf8156 pubmed publisher |
| Ma L, Tang Q, Gao X, Lee J, Lei R, Suzuki M, et al. Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis. Sci Adv. 2022;8:eabm3470 pubmed publisher |
| Young I, Wu B, Andricovich J, Chuang S, Li R, Tzatsos A, et al. Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling. Cell Rep. 2021;37:110036 pubmed publisher |
| Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, et al. Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death. Front Immunol. 2021;12:722273 pubmed publisher |
| Cui Y, Wang Y, Song X, Ning H, Zhang Y, Teng Y, et al. Brain endothelial PTEN/AKT/NEDD4-2/MFSD2A axis regulates blood-brain barrier permeability. Cell Rep. 2021;36:109327 pubmed publisher |
| Ho T, Dellorusso P, Verovskaya E, Bakker S, Flach J, Smith L, et al. Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions. J Exp Med. 2021;218: pubmed publisher |
| Seydoux E, Wan Y, Feng J, Wall A, Aljedani S, Homad L, et al. Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies. Cell Rep. 2021;35:109084 pubmed publisher |
| Rivas M, Meydan C, Chin C, Challman M, Kim D, Bhinder B, et al. Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. Nat Immunol. 2021;22:240-253 pubmed publisher |
| Scharenberg S, Poletto E, Lucot K, Colella P, Sheikali A, Montine T, et al. Engineering monocyte/macrophage-specific glucocerebrosidase expression in human hematopoietic stem cells using genome editing. Nat Commun. 2020;11:3327 pubmed publisher |
| Wu L, Hollinshead K, Hao Y, Au C, Kroehling L, Ng C, et al. Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy. Cell. 2020;182:641-654.e20 pubmed publisher |
| Shen C, Sheng Y, Zhu A, Robinson S, Jiang X, Dong L, et al. RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia. Cell Stem Cell. 2020;27:64-80.e9 pubmed publisher |
| Gadomski S, Singh S, Singh S, Sarkar T, Klarmann K, Berenschot M, et al. Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration. Cell Rep. 2020;31:107572 pubmed publisher |
| Di Genua C, Valletta S, Buono M, Stoilova B, Sweeney C, Rodriguez Meira A, et al. C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor. Cancer Cell. 2020;37:690-704.e8 pubmed publisher |
| Rana A, de Almeida F, Paico Montero H, Gonzales Carazas M, Bortoluci K, Sad S, et al. RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes. Front Immunol. 2020;11:536 pubmed publisher |
| Kang Y, Pietras E, Passegue E. Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia. J Exp Med. 2020;217: pubmed publisher |
| Wang J, Cui Y, Yu Z, Wang W, Cheng X, Ji W, et al. Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis. Cell Stem Cell. 2019;25:754-767.e9 pubmed publisher |
| Tong D, Zhang L, Ning F, Xu Y, Hu X, Shi Y. Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival. Protein Cell. 2020;11:108-123 pubmed publisher |
| Yamashita M, Passegue E. TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration. Cell Stem Cell. 2019;: pubmed publisher |
| Kolter J, Feuerstein R, Zeis P, Hagemeyer N, Paterson N, d Errico P, et al. A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves. Immunity. 2019;50:1482-1497.e7 pubmed publisher |
| Ni F, Yu W, Wang X, Fay M, Young K, Qiu Y, et al. Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics. Cell Stem Cell. 2019;24:608-620.e6 pubmed publisher |
| Zwick M, Ulas T, Cho Y, Ried C, Grosse L, Simon C, et al. Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells. Front Immunol. 2019;10:222 pubmed publisher |
| Dahl S, Woodworth J, Lerche C, Cramer E, Nielsen P, Moser C, et al. Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis. Front Immunol. 2018;9:2717 pubmed publisher |
| Beneke V, Küster F, Neehus A, Hesse C, Lopez Rodriguez E, Haake K, et al. An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages. Sci Rep. 2018;8:16281 pubmed publisher |
| Schmidt K, Zhang Q, Tasdogan A, Petzold A, Dahl A, Arneth B, et al. The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice. elife. 2018;7: pubmed publisher |
| Prendergast K, Daniels N, Petersen T, Hermans I, Kirman J. Langerin+ CD8α+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection. Front Immunol. 2018;9:953 pubmed publisher |
| Mitchell K, Barreyro L, Todorova T, Taylor S, Antony Debré I, Narayanagari S, et al. IL1RAP potentiates multiple oncogenic signaling pathways in AML. J Exp Med. 2018;215:1709-1727 pubmed publisher |
| Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher |
| Guo M, Price M, Patterson D, Barwick B, Haines R, Kania A, et al. EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production. J Immunol. 2018;200:1039-1052 pubmed publisher |
| Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed publisher |
| Essig K, Hu D, Guimaraes J, Alterauge D, Edelmann S, Raj T, et al. Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells. Immunity. 2017;47:1067-1082.e12 pubmed publisher |
| Delás M, Sabin L, Dolzhenko E, Knott S, Munera Maravilla E, Jackson B, et al. lncRNA requirements for mouse acute myeloid leukemia and normal differentiation. elife. 2017;6: pubmed publisher |
| Zaid A, Hor J, Christo S, Groom J, Heath W, Mackay L, et al. Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation. J Immunol. 2017;199:2451-2459 pubmed publisher |
| Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed publisher |
| Zhao Y, Wu K, Nguyen C, Smbatyan G, Melendez E, Higuchi Y, et al. Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation. PLoS ONE. 2017;12:e0177245 pubmed publisher |
| Hérault A, Binnewies M, Leong S, Calero Nieto F, Zhang S, Kang Y, et al. Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature. 2017;544:53-58 pubmed publisher |
| Ambrosi T, Scialdone A, Graja A, Gohlke S, Jank A, Bocian C, et al. Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration. Cell Stem Cell. 2017;20:771-784.e6 pubmed publisher |
| Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed publisher |
| Schmitt M, Sitte S, Voehringer D. CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection. Front Immunol. 2016;7:622 pubmed publisher |
| Hahm E, Wei C, Fernandez I, Li J, Tardi N, Tracy M, et al. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nat Med. 2017;23:100-106 pubmed publisher |
| Zamora Pineda J, Kumar A, Suh J, Zhang M, Saba J. Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. J Exp Med. 2016;213:2773-2791 pubmed |
| Hilpert C, Sitte S, Matthies A, Voehringer D. Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection. J Immunol. 2016;197:2780-6 pubmed publisher |
| Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher |
| Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed publisher |
| Barrett N, Malouf C, Kapeni C, Bacon W, Giotopoulos G, Jacobsen S, et al. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016;16:1039-1054 pubmed publisher |
| Ghosh M, Shapiro L. In vitro Ag Cross-presentation and in vivo Ag Cross-presentation by Dendritic Cells in the Mouse. Bio Protoc. 2012;2:e305 pubmed |
| Kazemi Z, Bergmayr C, Prchal Murphy M, Javaheri T, Themanns M, Pham H, et al. Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation. Mol Pharmacol. 2016;89:630-44 pubmed publisher |
| Matsuo Y, Mizoguchi F, Saito T, Kawahata K, Ueha S, Matsushima K, et al. Local fibroblast proliferation but not influx is responsible for synovial hyperplasia in a murine model of rheumatoid arthritis. Biochem Biophys Res Commun. 2016;470:504-509 pubmed publisher |
| Dileepan T, Smith E, Knowland D, Hsu M, Platt M, Bittner Eddy P, et al. Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells. J Clin Invest. 2016;126:303-17 pubmed publisher |
| Wu L, Li N, Zhang M, Xue S, Cassady K, Lin Q, et al. MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice. Proc Natl Acad Sci U S A. 2015;112:15994-9 pubmed publisher |
| Dudek M, Puttur F, Arnold Schrauf C, Kühl A, Holzmann B, Henriques Normark B, et al. Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection. Mucosal Immunol. 2016;9:1288-302 pubmed publisher |
| Gur Cohen S, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, et al. PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nat Med. 2015;21:1307-17 pubmed publisher |
| Alvarez S, Diaz M, Flach J, Rodriguez Acebes S, López Contreras A, Martinez D, et al. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun. 2015;6:8548 pubmed publisher |
| Xue J, Sharma V, Hsieh M, Chawla A, Murali R, Pandol S, et al. Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. Nat Commun. 2015;6:7158 pubmed publisher |
| Johnson H, Willenbring R, Jin F, Manhart W, Lafrance S, Pirko I, et al. Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption. PLoS ONE. 2014;9:e111401 pubmed publisher |
| Bruns I, Lucas D, Pinho S, Ahmed J, Lambert M, Kunisaki Y, et al. Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nat Med. 2014;20:1315-20 pubmed publisher |
| Xia P, Wang S, Huang G, Zhu P, Li M, Ye B, et al. WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner. J Exp Med. 2014;211:2119-34 pubmed publisher |
| Flach J, Bakker S, Mohrin M, Conroy P, Pietras E, Reynaud D, et al. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 2014;512:198-202 pubmed publisher |
| Haldar M, Kohyama M, So A, Kc W, Wu X, Briseño C, et al. Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell. 2014;156:1223-1234 pubmed publisher |
| Velu C, Chaubey A, Phelan J, Horman S, Wunderlich M, Guzman M, et al. Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. J Clin Invest. 2014;124:222-36 pubmed publisher |
| Rubinstein M, Salem M, Doedens A, Moore C, Chiuzan C, Rivell G, et al. G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses. J Hematol Oncol. 2013;6:75 pubmed publisher |
| Hu G, Tang Q, Sharma S, Yu F, Escobar T, Muljo S, et al. Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation. Nat Immunol. 2013;14:1190-8 pubmed publisher |
| Adorno M, Sikandar S, Mitra S, Kuo A, Nicolis Di Robilant B, Haro Acosta V, et al. Usp16 contributes to somatic stem-cell defects in Down's syndrome. Nature. 2013;501:380-4 pubmed publisher |
| Nikbakht N, Shen S, Manser T. Cutting edge: Macrophages are required for localization of antigen-activated B cells to the follicular perimeter and the subsequent germinal center response. J Immunol. 2013;190:4923-7 pubmed publisher |
| Grosselin J, Sii Felice K, Payen E, Chretien S, Tronik Le Roux D, Leboulch P. Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics. Stem Cells. 2013;31:2162-71 pubmed publisher |
| Gigi V, Stein J, Askenasy N, Yaniv I, Ash S. Early immunisation with dendritic cells after allogeneic bone marrow transplantation elicits graft vs tumour reactivity. Br J Cancer. 2013;108:1092-9 pubmed publisher |
| Warr M, Binnewies M, Flach J, Reynaud D, Garg T, Malhotra R, et al. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature. 2013;494:323-7 pubmed publisher |
| Reis B, Rogoz A, Costa Pinto F, Taniuchi I, Mucida D. Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4? T cell immunity. Nat Immunol. 2013;14:271-80 pubmed publisher |
| Ma D, Suthar M, Kasahara S, Gale M, Clark E. CD22 is required for protection against West Nile virus Infection. J Virol. 2013;87:3361-75 pubmed publisher |
| Strainic M, Shevach E, An F, Lin F, Medof M. Absence of signaling into CD4? cells via C3aR and C5aR enables autoinductive TGF-?1 signaling and induction of Foxp3? regulatory T cells. Nat Immunol. 2013;14:162-71 pubmed publisher |
| Dahlem T, Cho S, Spangrude G, Weis J, Weis J. Overexpression of Snai3 suppresses lymphoid- and enhances myeloid-cell differentiation. Eur J Immunol. 2012;42:1038-43 pubmed publisher |
| Lee S, Li X, Kim J, Lee J, Gonzalez Navajas J, Hong S, et al. Type I interferons maintain Foxp3 expression and T-regulatory cell functions under inflammatory conditions in mice. Gastroenterology. 2012;143:145-54 pubmed publisher |
| Li Z, Huang H, Li Y, Jiang X, Chen P, Arnovitz S, et al. Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. Blood. 2012;119:2314-24 pubmed publisher |
| Lee E, Chanamara S, Pleasure D, Soulika A. IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci. J Neuroinflammation. 2012;9:7 pubmed publisher |
| Martinez R, Zhang N, Thomas S, Nandiwada S, Jenkins M, Binstadt B, et al. Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells. J Immunol. 2012;188:170-81 pubmed publisher |
| Barao I, Alvarez M, Redelman D, Weiss J, Ortaldo J, Wiltrout R, et al. Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2011;17:1754-64 pubmed publisher |
| Serre K, Bénézech C, Desanti G, Bobat S, Toellner K, Bird R, et al. Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression. PLoS ONE. 2011;6:e20731 pubmed publisher |
| Simkins H, Hyde E, Farrand K, Ong M, Degli Esposti M, Hermans I, et al. Administration of alpha-galactosylceramide impairs the survival of dendritic cell subpopulations in vivo. J Leukoc Biol. 2011;89:753-62 pubmed publisher |
| Tatum A, Watson A, Schell T. Direct presentation regulates the magnitude of the CD8+ T cell response to cell-associated antigen through prolonged T cell proliferation. J Immunol. 2010;185:2763-72 pubmed publisher |
| Gerlach C, van Heijst J, Swart E, Sie D, Armstrong N, Kerkhoven R, et al. One naive T cell, multiple fates in CD8+ T cell differentiation. J Exp Med. 2010;207:1235-46 pubmed publisher |
| Shimada K, Chen S, Dempsey P, Sorrentino R, Alsabeh R, Slepenkin A, et al. The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection. PLoS Pathog. 2009;5:e1000379 pubmed publisher |
| Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger E, et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol. 2009;182:259-73 pubmed |
| Rubinstein M, Lind N, Purton J, Filippou P, Best J, McGhee P, et al. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 2008;112:3704-12 pubmed publisher |
| Yorty J, Tevethia S, Schell T. Rapid accumulation of adoptively transferred CD8+ T cells at the tumor site is associated with long-term control of SV40 T antigen-induced tumors. Cancer Immunol Immunother. 2008;57:883-95 pubmed |
| Cho J, Boyman O, Kim H, Hahm B, Rubinstein M, Ramsey C, et al. An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2. J Exp Med. 2007;204:1787-801 pubmed |
| Weisberg S, McCann D, Desai M, Rosenbaum M, Leibel R, Ferrante A. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112:1796-808 pubmed |
