CD25 Monoclonal Antibody (OX39), PE, eBioscience™ | Invitrogen 12-0390-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD25 Monoclonal Antibody (OX39), PE, eBioscience™

catalog :

12-0390-80

quantity :

25 µg

price :

US 84.25

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

OX39

reactivity :

rat

application :

flow cytometry

citations: 10

Reference
Yin M, Shen Z, Yang L, Zheng W, Song H. Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway. Int J Mol Med. 2019;43:2086-2102 pubmed publisher
Jiao Y, Tan S, Xiong J. Proteomic changes of CD4+/CD25+/forkhead box p3+ regulatory T cells in a 30-day rat model of sepsis survival. Exp Ther Med. 2017;14:5619-5628 pubmed publisher
Zhang Y, Meng Q, Zhang Y, Chen X, Wang Y. Adipose-derived mesenchymal stem cells suppress of acute rejection in small bowel transplantation. Saudi J Gastroenterol. 2017;23:323-329 pubmed publisher
Xie L, Zhong X, Liu D, Liu L, Xia Z. The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model. BMC Complement Altern Med. 2017;17:511 pubmed publisher
Li Y, Li H, Cao Y, Wu F, Ma W, Wang Y, et al. Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance. Mol Med Rep. 2017;16:8137-8145 pubmed publisher
Hu G, Yang S, Hu W, Wen Z, He D, Zeng L, et al. Effect of cold stress on immunity in rats. Exp Ther Med. 2016;11:33-42 pubmed
Oliveira L, Correia A, Cristina Costa A, Guerra Gomes S, Ferreirinha F, MagalhÃ£es Cardoso M, et al. Deficits in endogenous adenosine formation by ecto-5'-nucleotidase/CD73 impair neuromuscular transmission and immune competence in experimental autoimmune myasthenia gravis. Mediators Inflamm. 2015;2015:460610 pubmed publisher
Wu Y, Ye Q, Eytan D, Liu L, Rosario B, Hitchens T, et al. Magnetic resonance imaging investigation of macrophages in acute cardiac allograft rejection after heart transplantation. Circ Cardiovasc Imaging. 2013;6:965-73 pubmed publisher
Kang J, de Brito Bezerra B, Pacios S, Andriankaja O, Li Y, TSIAGBE V, et al. Aggregatibacter actinomycetemcomitans infection enhances apoptosis in vivo through a caspase-3-dependent mechanism in experimental periodontitis. Infect Immun. 2012;80:2247-56 pubmed publisher
Bezerra B, Andriankaja O, Kang J, Pacios S, Bae H, Li Y, et al. A.actinomycetemcomitans-induced periodontal disease promotes systemic and local responses in rat periodontium. J Clin Periodontol. 2012;39:333-41 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD25 Monoclonal Antibody (OX39), PE, eBioscience™

Catalog # :

12-0390-80

Quantity :

25 µg

Price :

US 84.25

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Rat

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Rat

Clone :

OX39

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2 plays an important role as a growth factor, differentiation factor, and regulator of cell death. IL-2 stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocyte macrophage colony formation. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

CD25; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR