This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human Lin28-TAT Recombinant Protein, PeproTech
catalog :
110-06-500UG
quantity :
500 ug
price :
US 2090.00
citations: 1
Reference
Tan F, Sathe S, Wheeler E, Yeo G. Non-microRNA binding competitively inhibits LIN28 regulation. Cell Rep. 2021;36:109517 pubmed publisher
product information
Product Type :
Protein
Product Name :
Human Lin28-TAT Recombinant Protein, PeproTech
Catalog # :
110-06-500UG
Quantity :
500 ug
Price :
US 2090.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Functional Assay: Assay-dependent
Species :
Human
Storage :
-20 C
Description :
Lin28 is a RNA-binding protein that belongs to a diverse family of structurally-related transcription factors. Lin28 is found abundantly in embryonic stem cells (ESCs), and to a lesser extent in placenta and testis. Lin28 has been shown to block let-7 microRNA processing and maturation, a necessary step in the differentiation of stem cells and certain cancer cell lines. Together with Sox2, Oct4, and Nanog, Lin28 can induce the reprogramming of primary human fibroblasts to a pluripotent state. Lin28 and other regulatory proteins can be introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing proteins into primary, as well as transformed, cells.
Format :
Lyophilized
Applications w/Dilutions :
Functional Assay: Assay-dependent
Aliases :
LIN28A
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA