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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GM-CSF Monoclonal Antibody (MP1-22E9), FITC, eBioscience™
catalog :
11-7331-82
quantity :
100 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
MP1-22E9
reactivity :
mouse
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 18
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig 5
Ward L, Lee D, Sharma A, Wang A, Naouar I, Ma X, et al. Siponimod therapy implicates Th17 cells in a preclinical model of subpial cortical injury. JCI Insight. 2020;5: pubmed publisher
Palmer B, Phelan Dickenson S, Delouise L. Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation. Part Fibre Toxicol. 2019;16:3 pubmed publisher
Wildes T, Grippin A, Dyson K, Wummer B, Damiani D, Abraham R, et al. Cross-talk between T Cells and Hematopoietic Stem Cells during Adoptive Cellular Therapy for Malignant Glioma. Clin Cancer Res. 2018;24:3955-3966 pubmed publisher
Anstadt E, Fujiwara M, Wasko N, Nichols F, Clark R. TLR Tolerance as a Treatment for Central Nervous System Autoimmunity. J Immunol. 2016;197:2110-8 pubmed publisher
Shiomi A, Usui T, Ishikawa Y, Shimizu M, Murakami K, Mimori T. GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice. J Immunol. 2014;193:849-59 pubmed publisher
Sánchez Vallecillo M, Ullio Gamboa G, Palma S, Harman M, Chiodetti A, Moron G, et al. Adjuvant activity of CpG-ODN formulated as a liquid crystal. Biomaterials. 2014;35:2529-42 pubmed publisher
Samavedam U, Iwata H, Müller S, Schulze F, Recke A, Schmidt E, et al. GM-CSF modulates autoantibody production and skin blistering in experimental epidermolysis bullosa acquisita. J Immunol. 2014;192:559-71 pubmed publisher
Lee P, Puppi M, Schluns K, Yu Lee L, Dong C, Lacorazza H. The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage. J Immunol. 2014;192:178-88 pubmed publisher
Othy S, Hegde P, Topçu S, Sharma M, Maddur M, Lacroix Desmazes S, et al. Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine-1 phosphate receptor 1-mammalian target of rapamycin axis. J Immunol. 2013;190:4535-41 pubmed publisher
Kamei A, Wu W, Traficante D, Koh A, Van Rooijen N, Pier G, et al. Collaboration between macrophages and vaccine-induced CD4+ T cells confers protection against lethal Pseudomonas aeruginosa pneumonia during neutropenia. J Infect Dis. 2013;207:39-49 pubmed publisher
Massilamany C, Asojo O, Gangaplara A, Steffen D, Reddy J. Identification of a second mimicry epitope from Acanthamoeba castellanii that induces CNS autoimmunity by generating cross-reactive T cells for MBP 89-101 in SJL mice. Int Immunol. 2011;23:729-39 pubmed publisher
Yeh W, McWilliams I, Harrington L. Autoreactive Tbet-positive CD4 T cells develop independent of classic Th1 cytokine signaling during experimental autoimmune encephalomyelitis. J Immunol. 2011;187:4998-5006 pubmed publisher
Massilamany C, Gangaplara A, Steffen D, Reddy J. Identification of novel mimicry epitopes for cardiac myosin heavy chain-? that induce autoimmune myocarditis in A/J mice. Cell Immunol. 2011;271:438-49 pubmed publisher
Khajah M, Millen B, Cara D, Waterhouse C, McCafferty D. Granulocyte-macrophage colony-stimulating factor (GM-CSF): a chemoattractive agent for murine leukocytes in vivo. J Leukoc Biol. 2011;89:945-53 pubmed publisher
Wu H, Suzuki T, Carey B, Trapnell B, McCormack F. Keratinocyte growth factor augments pulmonary innate immunity through epithelium-driven, GM-CSF-dependent paracrine activation of alveolar macrophages. J Biol Chem. 2011;286:14932-40 pubmed publisher
Nijnik A, Madera L, Ma S, Waldbrook M, Elliott M, Easton D, et al. Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment. J Immunol. 2010;184:2539-50 pubmed publisher
Zhu S, Chen M, Jongstra Bilen J, Cybulsky M. GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions. J Exp Med. 2009;206:2141-9 pubmed publisher
Jiang D, Chen Y, Schwarz H. CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages. J Immunol. 2008;181:3923-32 pubmed
product information
Product Type :
Antibody
Product Name :
GM-CSF Monoclonal Antibody (MP1-22E9), FITC, eBioscience™
Catalog # :
11-7331-82
Quantity :
100 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Mouse
Clone :
MP1-22E9
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA