This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-6 Monoclonal Antibody (MQ2-13A5), FITC, eBioscience
catalog :
11-7069-82
quantity :
100 ug
price :
US 316.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
MQ2-13A5

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 25
Reference
Ahmed A, Tripathi H, van Meijgaarden K, Kumar N, Adiga V, Rakshit S, et al. BCG revaccination in adults enhances pro-inflammatory markers of trained immunity along with anti-inflammatory pathways. iScience. 2023;26:107889 pubmed publisher
Jiang Q, Bai G, Liu X, Chen Y, Xu G, Yang C, et al. 3D GelMA ICC Scaffolds Combined with SW033291 for Bone Regeneration by Modulating Macrophage Polarization. Pharmaceutics. 2021;13: pubmed publisher
Obst J, Hall Roberts H, Smith T, Kreuzer M, Magno L, Di Daniel E, et al. PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages. Sci Rep. 2021;11:19842 pubmed publisher
Zhang G, Jiao Q, Shen C, Song H, Zhang H, Qiu Z, et al. Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer. Cancer Sci. 2021;112:997-1010 pubmed publisher
Ramakrishnan S, Hu Q, Krishnan N, Wang D, Smit E, Granger V, et al. Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer. Cell Death Dis. 2017;8:3217 pubmed publisher
Jiang C, Zhang Q, Shanti R, Shi S, Chang T, Carrasco L, et al. Mesenchymal Stromal Cell-Derived Interleukin-6 Promotes Epithelial-Mesenchymal Transition and Acquisition of Epithelial Stem-Like Cell Properties in Ameloblastoma Epithelial Cells. Stem Cells. 2017;35:2083-2094 pubmed publisher
Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai W, et al. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A. 2016;113:10127-32 pubmed publisher
Clay C, Maniar Hew K, Gerriets J, Wang T, Postlethwait E, Evans M, et al. Early life ozone exposure results in dysregulated innate immune function and altered microRNA expression in airway epithelium. PLoS ONE. 2014;9:e90401 pubmed publisher
Reichwald K, Jørgensen T, Tougaard P, Skov S. TL1A induces TCR independent IL-6 and TNF-? production and growth of PLZF? leukocytes. PLoS ONE. 2014;9:e85793 pubmed publisher
Marr N, Wang T, Kam S, Hu Y, Sharma A, Lam A, et al. Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children. J Immunol. 2014;192:948-57 pubmed publisher
Krishnan S, Wilson E, Sheikh V, Rupert A, Mendoza D, Yang J, et al. Evidence for innate immune system activation in HIV type 1-infected elite controllers. J Infect Dis. 2014;209:931-9 pubmed publisher
Nagy L, Grishina I, Macal M, Hirao L, Hu W, Sankaran Walters S, et al. Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal Lactobacillus. PLoS ONE. 2013;8:e72789 pubmed publisher
Spaan M, Groothuismink Z, Koning L, Roomer R, Janssen H, de Knegt R, et al. Erythropoietin administration suppresses human monocyte function in vitro and during therapy-induced anemia in HCV patients. Antiviral Res. 2013;98:469-75 pubmed publisher
Yeh C, Yeh T, Jung C, Chen P, Lien H, Chia J. Activated human nasal epithelial cells modulate specific antibody response against bacterial or viral antigens. PLoS ONE. 2013;8:e55472 pubmed publisher
Jaudszus A, Gruen M, Watzl B, Ness C, Roth A, Lochner A, et al. Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells. J Lipid Res. 2013;54:923-35 pubmed publisher
Vohra P, Poxton I. Induction of cytokines in a macrophage cell line by proteins of Clostridium difficile. FEMS Immunol Med Microbiol. 2012;65:96-104 pubmed publisher
Sauer U, Domnanich P, Preininger C. Protein chip for the parallel quantification of high and low abundant biomarkers for sepsis. Anal Biochem. 2011;419:46-52 pubmed publisher
Frazer L, O Connell C, Andrews C, Zurenski M, Darville T. Enhanced neutrophil longevity and recruitment contribute to the severity of oviduct pathology during Chlamydia muridarum infection. Infect Immun. 2011;79:4029-41 pubmed publisher
Domnanich P, Peña D, Preininger C. Xanthan/chitosan gold chip for metal enhanced protein biomarker detection. Biosens Bioelectron. 2011;26:2559-65 pubmed publisher
Ma C, Ni L, Zhang Y, Zhang C, Wu X, Atia A, et al. PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages during chronic hepatitis C virus infection. Immunology. 2011;132:421-31 pubmed publisher
Veltkamp M, van Moorsel C, Rijkers G, Ruven H, van den Bosch J, Grutters J. Toll-like receptor (TLR)-9 genetics and function in sarcoidosis. Clin Exp Immunol. 2010;162:68-74 pubmed publisher
Wang J, Huizinga T, Toes R. De novo generation and enhanced suppression of human CD4+CD25+ regulatory T cells by retinoic acid. J Immunol. 2009;183:4119-26 pubmed publisher
Floriano P, Christodoulides N, Miller C, Ebersole J, Spertus J, Rose B, et al. Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study. Clin Chem. 2009;55:1530-8 pubmed publisher
Yan B, Ye S, Chen G, Kuang M, Shen N, Chen S. Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells. Arthritis Rheum. 2008;58:801-12 pubmed publisher
Barrionuevo P, Cassataro J, Delpino M, Zwerdling A, Pasquevich K, García Samartino C, et al. Brucella abortus inhibits major histocompatibility complex class II expression and antigen processing through interleukin-6 secretion via Toll-like receptor 2. Infect Immun. 2008;76:250-62 pubmed
product information
Product Type :
Antibody
Product Name :
IL-6 Monoclonal Antibody (MQ2-13A5), FITC, eBioscience
Catalog # :
11-7069-82
Quantity :
100 ug
Price :
US 316.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Human
Clone :
MQ2-13A5
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA