IgE Monoclonal Antibody (23G3), FITC, eBioscience | Invitrogen 11-5992-81 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IgE Monoclonal Antibody (23G3), FITC, eBioscience

catalog :

11-5992-81

quantity :

50 ug

price :

US 117.00

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

23G3

application :

flow cytometry

citations: 20

Reference
Smith N, Germundson D, Combs C, Vendsel L, Nagamoto Combs K. Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy. Front Cell Neurosci. 2019;13:320 pubmed publisher
Meixiong J, Anderson M, Limjunyawong N, Sabbagh M, Hu E, Mack M, et al. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity. 2019;50:1163-1171.e5 pubmed publisher
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
Hwang Y, Yun M, Jeong K, Park J. Uremic toxin indoxyl 3-sulfate regulates the differentiation of Th2 but not of Th1 cells to lessen allergic asthma. Toxicol Lett. 2014;225:130-8 pubmed publisher
Metcalf D, Ng A, Baldwin T, Di Rago L, Mifsud S. Concordant mast cell and basophil production by individual hematopoietic blast colony-forming cells. Proc Natl Acad Sci U S A. 2013;110:9031-5 pubmed publisher
Burton O, Darling A, Zhou J, Noval Rivas M, Jones T, Gurish M, et al. Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy. Mucosal Immunol. 2013;6:740-50 pubmed publisher
Song Y, Qu C, Srivastava K, Yang N, Busse P, Zhao W, et al. Food allergy herbal formula 2 protection against peanut anaphylactic reaction is via inhibition of mast cells and basophils. J Allergy Clin Immunol. 2010;126:1208-17.e3 pubmed publisher
Cheng L, Wang Z, Locksley R. Murine B cells regulate serum IgE levels in a CD23-dependent manner. J Immunol. 2010;185:5040-7 pubmed publisher
Mai T, Zan H, Zhang J, Hawkins J, Xu Z, Casali P. Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation. J Biol Chem. 2010;285:37797-810 pubmed publisher
Kim H, Lee D, Lee S, Seong A, Gin D, Hwang J, et al. Chlorogenic acid suppresses pulmonary eosinophilia, IgE production, and Th2-type cytokine production in an ovalbumin-induced allergic asthma: activation of STAT-6 and JNK is inhibited by chlorogenic acid. Int Immunopharmacol. 2010;10:1242-8 pubmed publisher
Ota T, Aoki Ota M, Duong B, Nemazee D. Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE. J Immunol. 2009;182:8110-7 pubmed publisher
Khramova D, Popov S, Golovchenko V, Vityazev F, Paderin N, Ovodov Y. Abrogation of the oral tolerance to ovalbumin in mice by citrus pectin. Nutrition. 2009;25:226-32 pubmed publisher
Sadri N, Schneider R. Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol. 2009;129:657-70 pubmed publisher
Ryzhov S, Zaynagetdinov R, Goldstein A, Novitskiy S, Dikov M, Blackburn M, et al. Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells. J Immunol. 2008;180:7212-20 pubmed
Mori T, Kabashima K, Yoshiki R, Sugita K, Shiraishi N, Onoue A, et al. Cutaneous hypersensitivities to hapten are controlled by IFN-gamma-upregulated keratinocyte Th1 chemokines and IFN-gamma-downregulated langerhans cell Th2 chemokines. J Invest Dermatol. 2008;128:1719-27 pubmed publisher
Nagata T, Toyota T, Ishigaki H, Ichihashi T, Kajino K, Kashima Y, et al. Peptides coupled to the surface of a kind of liposome protect infection of influenza viruses. Vaccine. 2007;25:4914-21 pubmed
Taketomi Y, Sunaga K, Tanaka S, Nakamura M, Arata S, Okuda T, et al. Impaired mast cell maturation and degranulation and attenuated allergic responses in Ndrg1-deficient mice. J Immunol. 2007;178:7042-53 pubmed
Obata K, Mukai K, Tsujimura Y, Ishiwata K, Kawano Y, Minegishi Y, et al. Basophils are essential initiators of a novel type of chronic allergic inflammation. Blood. 2007;110:913-20 pubmed
Popov S, Golovchenko V, Ovodova R, Smirnov V, Khramova D, Popova G, et al. Characterisation of the oral adjuvant effect of lemnan, a pectic polysaccharide of Lemna minor L. Vaccine. 2006;24:5413-9 pubmed
Popov S, Günter E, Markov P, Smirnov V, Khramova D, Ovodov Y. Adjuvant effect of lemnan, pectic polysaccharide of callus culture of Lemna minor L. at oral administration. Immunopharmacol Immunotoxicol. 2006;28:141-52 pubmed

product information

Product Type :

Antibody

Product Name :

IgE Monoclonal Antibody (23G3), FITC, eBioscience

Catalog # :

11-5992-81

Quantity :

50 ug

Price :

US 117.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 ug/test

Species :

Mouse

Clone :

23G3

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with 4 Ig-like constant domains, and two light chains. IgE plays an essential role in type I hypersensitivity (allergic responses such as hay fever, asthma, hives, anaphylatic shock) by binding to Fc receptors on basophils and mast cells. Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils that promote allergic manifestations. IgE is also functionally important for immunity against parasites.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test

Aliases :

Gm900; Ighe; Immunoglobulin E; Immunoglobulin heavy constant epsilon; ImmunoglobulinE