This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ly-49I Monoclonal Antibody (YLI-90), FITC, eBioscience
catalog :
11-5895-82
quantity :
100 ug
price :
US 164.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
YLI-90

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 15
Reference
Li S, Bern M, Miao B, Fan C, Xing X, Inoue T, et al. The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function. elife. 2022;11: pubmed publisher
Potempa M, Aguilar O, Gonzalez Hinojosa M, Tenvooren I, Marquez D, Spitzer M, et al. Influence of Self-MHC Class I Recognition on the Dynamics of NK Cell Responses to Cytomegalovirus Infection. J Immunol. 2022;208:1742-1754 pubmed publisher
Yang E, Singh B, Paustian A, Kambayashi T. Diacylglycerol Kinase ? Is a Target To Enhance NK Cell Function. J Immunol. 2016;197:934-41 pubmed publisher
Kieckbusch J, Gaynor L, Moffett A, Colucci F. MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling. Nat Commun. 2014;5:3359 pubmed publisher
Lee G, Liou Y, Wang S, Ko K, Jiang S, Liao N. Different NK cell developmental events require different levels of IL-15 trans-presentation. J Immunol. 2011;187:1212-21 pubmed publisher
Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam L, Chrzanowska Wodnicka M, et al. Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. J Exp Med. 2010;207:1923-38 pubmed publisher
Jonsson A, Yang L, Kim S, Taffner S, Yokoyama W. Effects of MHC class I alleles on licensing of Ly49A+ NK cells. J Immunol. 2010;184:3424-32 pubmed publisher
Brenner C, King S, Przewoznik M, Wolters I, Adam C, Bornkamm G, et al. Requirements for control of B-cell lymphoma by NK cells. Eur J Immunol. 2010;40:494-504 pubmed publisher
Joncker N, Fernandez N, Treiner E, Vivier E, Raulet D. NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J Immunol. 2009;182:4572-80 pubmed publisher
Guo H, Samarakoon A, Vanhaesebroeck B, Malarkannan S. The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. J Exp Med. 2008;205:2419-35 pubmed publisher
Malarkannan S, Regunathan J, Chu H, Kutlesa S, Chen Y, Zeng H, et al. Bcl10 plays a divergent role in NK cell-mediated cytotoxicity and cytokine generation. J Immunol. 2007;179:3752-62 pubmed
Lu L, Zavitz C, Chen B, Kianpour S, Wan Y, Stampfli M. Cigarette smoke impairs NK cell-dependent tumor immune surveillance. J Immunol. 2007;178:936-43 pubmed
Taki S, Nakajima S, Ichikawa E, Saito T, Hida S. IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells. J Immunol. 2005;174:6005-12 pubmed
Regunathan J, Chen Y, Wang D, Malarkannan S. NKG2D receptor-mediated NK cell function is regulated by inhibitory Ly49 receptors. Blood. 2005;105:233-40 pubmed
Coles M, McMahon C, Takizawa H, Raulet D. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000;30:236-44 pubmed
product information
Product Type :
Antibody
Product Name :
Ly-49I Monoclonal Antibody (YLI-90), FITC, eBioscience
Catalog # :
11-5895-82
Quantity :
100 ug
Price :
US 164.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 ug/test
Species :
Mouse
Clone :
YLI-90
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test
Aliases :
5E6; Killer cell lectin-like receptor 3; killer cell lectin-like receptor subfamily A, member 9; Klra3; Klra9; Ly-49; Ly49C; Ly-49c; Ly49I; Ly49I receptor; Ly-49I receptor; LY49I1; Lymphocyte antigen 49c; Nk2.1; T-cell surface glycoprotein Ly-49C
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA