Ly-49G2 Monoclonal Antibody (eBio4D11 (4D11)), FITC, eBioscience™ | Invitrogen 11-5781-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ly-49G2 Monoclonal Antibody (eBio4D11 (4D11)), FITC, eBioscience™

catalog :

11-5781-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

eBio4D11 (4D11)

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s1a	Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 3d	Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed publisher
	Li Z, Song Z, Meng C, Yang D, Yang Y, Peng J. IFN-Î³ modulates Ly-49 receptors on NK cells in IFN-Î³-induced pregnancy failure. Sci Rep. 2015;5:18159 pubmed publisher
	Pyzik M, Dumaine A, Dumaine A, Charbonneau B, Fodil Cornu N, Jonjic S, et al. Viral MHC class I-like molecule allows evasion of NK cell effector responses in vivo. J Immunol. 2014;193:6061-9 pubmed publisher
	Sullivan R, Fogel L, Leong J, Schneider S, Wong R, Romee R, et al. MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pathways. J Immunol. 2013;191:5904-13 pubmed publisher
	McFall E, Tu M, Al Khattabi N, Tai L, St Laurent A, Tzankova V, et al. Optimized tetramer analysis reveals Ly49 promiscuity for MHC ligands. J Immunol. 2013;191:5722-9 pubmed publisher
	Ballas Z, Cook R, Shey M, Coleman R. A dynamic flux in natural killer cell subsets as a function of the duration of alcohol ingestion. Alcohol Clin Exp Res. 2012;36:826-34 pubmed publisher
	Pyzik M, Charbonneau B, Gendron Pontbriand E, Babic M, Krmpotic A, Jonjic S, et al. Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains. J Exp Med. 2011;208:1105-17 pubmed publisher
	Stadnisky M, Xie X, Coats E, BULLOCK T, Brown M. Self MHC class I-licensed NK cells enhance adaptive CD8 T-cell viral immunity. Blood. 2011;117:5133-41 pubmed publisher
	Luther C, Warner K, Takei F. Unique progenitors in mouse lymph node develop into CD127+ NK cells: thymus-dependent and thymus-independent pathways. Blood. 2011;117:4012-21 pubmed publisher
	Guo H, Topham D. Interleukin-22 (IL-22) production by pulmonary Natural Killer cells and the potential role of IL-22 during primary influenza virus infection. J Virol. 2010;84:7750-9 pubmed publisher
	Jonsson A, Yang L, Kim S, Taffner S, Yokoyama W. Effects of MHC class I alleles on licensing of Ly49A+ NK cells. J Immunol. 2010;184:3424-32 pubmed publisher
	Hirohashi T, Uehara S, Chase C, Dellapelle P, Madsen J, Russell P, et al. Complement independent antibody-mediated endarteritis and transplant arteriopathy in mice. Am J Transplant. 2010;10:510-7 pubmed publisher
	Fodil Cornu N, Pyzik M, Vidal S. Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus. Methods Mol Biol. 2010;612:393-409 pubmed publisher
	Castillo E, Stonier S, Frasca L, Schluns K. Dendritic cells support the in vivo development and maintenance of NK cells via IL-15 trans-presentation. J Immunol. 2009;183:4948-56 pubmed publisher
	Ohno S, Sato T, Kohu K, Takeda K, Okumura K, Satake M, et al. Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation. Int Immunol. 2008;20:71-9 pubmed
	Kitchens W, Chase C, Uehara S, Cornell L, Colvin R, Russell P, et al. Macrophage depletion suppresses cardiac allograft vasculopathy in mice. Am J Transplant. 2007;7:2675-82 pubmed
	Malarkannan S, Regunathan J, Chu H, Kutlesa S, Chen Y, Zeng H, et al. Bcl10 plays a divergent role in NK cell-mediated cytotoxicity and cytokine generation. J Immunol. 2007;179:3752-62 pubmed
	Boos M, Yokota Y, Eberl G, Kee B. Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J Exp Med. 2007;204:1119-30 pubmed
	Robbins S, Tessmer M, Van Kaer L, Brossay L. Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation. Eur J Immunol. 2005;35:757-65 pubmed
	Regunathan J, Chen Y, Wang D, Malarkannan S. NKG2D receptor-mediated NK cell function is regulated by inhibitory Ly49 receptors. Blood. 2005;105:233-40 pubmed
	Mason L, Ortaldo J, Young H, Kumar V, Bennett M, Anderson S. Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2). J Exp Med. 1995;182:293-303 pubmed

product information

Product Type :

Antibody

Product Name :

Ly-49G2 Monoclonal Antibody (eBio4D11 (4D11)), FITC, eBioscience™

Catalog # :

11-5781-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

eBio4D11 (4D11)

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

Killer cell lectin-like receptor 7; killer cell lectin-like receptor, subfamily A, member 7; Klra7; LGL-1; Ly49g; ly-49g; Ly49-g; Ly-49G.1; Ly-49G.2; Ly-49G.3; Ly49G.4; Ly49g1; Ly49g2; Ly49g4; Lymphocyte antigen 49g; T-cell surface glycoprotein Ly-49G

more info or order :

Invitrogen product webpage