FR4 Monoclonal Antibody (eBio12A5), FITC, eBioscience | Invitrogen 11-5445-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FR4 Monoclonal Antibody (eBio12A5), FITC, eBioscience

catalog :

11-5445-80

quantity :

25 ug

price :

US 198.00

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

eBio12A5

reactivity :

mouse

application :

flow cytometry

citations: 5

Reference
Jhala G, Chee J, Trivedi P, Selck C, Gurzov E, Graham K, et al. Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes. JCI Insight. 2016;1:e86065 pubmed publisher
Sanoja C, Carbajosa S, Fresno M, Girones N. Analysis of the dynamics of infiltrating CD4(+) T cell subsets in the heart during experimental Trypanosoma cruzi infection. PLoS ONE. 2013;8:e65820 pubmed publisher
Sugimoto N, Oida T, Hirota K, Nakamura K, Nomura T, Uchiyama T, et al. Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Int Immunol. 2006;18:1197-209 pubmed
Elnakat H, Ratnam M. Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Adv Drug Deliv Rev. 2004;56:1067-84 pubmed
Spiegelstein O, Eudy J, Finnell R. Identification of two putative novel folate receptor genes in humans and mouse. Gene. 2000;258:117-25 pubmed

product information

Product Type :

Antibody

Product Name :

FR4 Monoclonal Antibody (eBio12A5), FITC, eBioscience

Catalog # :

11-5445-80

Quantity :

25 ug

Price :

US 198.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 ug/test

Species :

Mouse

Clone :

eBio12A5

Isotype :

IgG2b, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/test

Aliases :

0910001L11Rik; C86255; Folate receptor 4; folate receptor 4 (delta); folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); folate receptor delta; Folate-binding protein 3; Folbp3; Folr4; FR-delta; IZUMO1 receptor protein JUNO; IZUMO1 receptor, JUNO; Izumo1r; Juno; probable folate receptor delta; sperm-egg fusion protein Juno