product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), FITC, eBioscience™
catalog :
11-5321-85
quantity :
500 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
M5/114.15.2
reactivity :
mouse
application :
western blot, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 166
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:300; loading ...; fig s3b
Kuriakose J, Redecke V, Guy C, Zhou J, Wu R, Ippagunta S, et al. Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis. J Clin Invest. 2019;129:2251-2265 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2b
Singla B, Ghoshal P, Lin H, Wei Q, Dong Z, Csanyi G. PKCδ-Mediated Nox2 Activation Promotes Fluid-Phase Pinocytosis of Antigens by Immature Dendritic Cells. Front Immunol. 2018;9:537 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4a
Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A, et al. Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS ONE. 2018;13:e0193737 pubmed publisher
  • western blot; mouse; loading ...; fig 5f
Liang W, Mao S, Sun S, Li M, Li Z, Yu R, et al. Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation. Front Immunol. 2018;9:78 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s1a
  • flow cytometry; mouse; fig 1a
Böttcher J, Bonavita E, Chakravarty P, Blees H, Cabeza Cabrerizo M, Sammicheli S, et al. NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control. Cell. 2018;172:1022-1037.e14 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Wang H, Mo L, Xiao X, An S, Liu X, Ba J, et al. Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model. Sci Rep. 2017;7:43322 pubmed publisher
  • flow cytometry; mouse; fig 5
Iwasaki Y, Sugita S, Mandai M, Yonemura S, Onishi A, Ito S, et al. Differentiation/Purification Protocol for Retinal Pigment Epithelium from Mouse Induced Pluripotent Stem Cells as a Research Tool. PLoS ONE. 2016;11:e0158282 pubmed publisher
  • flow cytometry; mouse
Yin Y, Qin T, Wang X, Lin J, Yu Q, Yang Q. CpG DNA assists the whole inactivated H9N2 influenza virus in crossing the intestinal epithelial barriers via transepithelial uptake of dendritic cell dendrites. Mucosal Immunol. 2015;8:799-814 pubmed publisher
  • flow cytometry; mouse; loading ...; fig S7
Kim J, Li W, Choi Y, Lewin S, Verbeke C, Dranoff G, et al. Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy. Nat Biotechnol. 2015;33:64-72 pubmed publisher
  • flow cytometry; mouse; fig 3
Nagano T, Edamatsu H, Kobayashi K, Takenaka N, Yamamoto M, Sasaki N, et al. Phospholipase cε, an effector of ras and rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma. PLoS ONE. 2014;9:e108373 pubmed publisher
  • flow cytometry; mouse
Martins K, Steffens J, Van Tongeren S, Wells J, Bergeron A, Dickson S, et al. Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation. PLoS ONE. 2014;9:e89735 pubmed publisher
  • flow cytometry; mouse
Ferret Bernard S, Castro Borges W, Dowle A, Sanin D, Cook P, Turner J, et al. Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling. J Proteomics. 2012;75:938-48 pubmed publisher
  • flow cytometry; mouse; fig 7
Carlow D, Gold M, Ziltener H. Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells. J Immunol. 2009;183:1155-65 pubmed publisher
Wang L, Li Y, Wang X, Wang P, Essandoh K, Cui S, et al. GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype. Cells. 2020;9: pubmed publisher
Dokoshi T, Zhang L, Li F, Nakatsuji T, Butcher A, Yoshida H, et al. Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection. Cell Rep. 2020;30:61-68.e4 pubmed publisher
Fang D, Tang Q, Kong Y, Wang Q, Gu J, Fang X, et al. MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment. J Immunother Cancer. 2019;7:327 pubmed publisher
Aires I, Madeira M, Boia R, Rodrigues Neves A, Martins J, Ambrósio A, et al. Intravitreal injection of adenosine A2A receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice. Sci Rep. 2019;9:17207 pubmed publisher
Gal Oz S, Maier B, Yoshida H, Seddu K, Elbaz N, Czysz C, et al. ImmGen report: sexual dimorphism in the immune system transcriptome. Nat Commun. 2019;10:4295 pubmed publisher
Wang Z, Chen J, Hu J, Zhang H, Xu F, He W, et al. cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity. J Clin Invest. 2019;129:4850-4862 pubmed publisher
Sheng W, Chauhan P, Hu S, Prasad S, Lokensgard J. Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain. Pain Res Manag. 2019;2019:1260353 pubmed publisher
Baptista A, Gola A, Huang Y, Milanez Almeida P, Torabi Parizi P, Urban J, et al. The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity. Immunity. 2019;50:1188-1201.e6 pubmed publisher
Zhou Y, Fu C, Kong Y, Pan D, Wang Y, Huang S, et al. Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models. Anticancer Drugs. 2019;30:909-916 pubmed publisher
Lee H, Kim K, Ryu J, Jeong H, Lee S, Kim M. Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland. Invest Ophthalmol Vis Sci. 2019;60:430-441 pubmed publisher
Zhou Z, Chen H, Xie R, Wang H, Li S, Xu Q, et al. Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer. Mol Oncol. 2019;13:873-893 pubmed publisher
Percopo C, Ma M, Brenner T, Krumholz J, Break T, Laky K, et al. Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection. J Immunol. 2019;202:871-882 pubmed publisher
Buxade M, Huerga Encabo H, Riera Borrull M, Quintana Gallardo L, López Cotarelo P, Tellechea M, et al. Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5. J Exp Med. 2018;215:2901-2918 pubmed publisher
Klein B, Mrowetz H, Barker C, Lange S, Rivera F, Aigner L. Age Influences Microglial Activation After Cuprizone-Induced Demyelination. Front Aging Neurosci. 2018;10:278 pubmed publisher
Bonacina F, Coe D, Wang G, Longhi M, Baragetti A, Moregola A, et al. Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation. Nat Commun. 2018;9:3083 pubmed publisher
Gnipp S, Mergia E, Puschkarow M, Bufe A, Koesling D, Peters M. Nitric oxide dependent signaling via cyclic GMP in dendritic cells regulates migration and T-cell polarization. Sci Rep. 2018;8:10969 pubmed publisher
Song N, Zhang T, Xu X, Lü Z, Yu X, Fang Y, et al. miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation. Front Physiol. 2018;9:790 pubmed publisher
Ates L, Sayes F, Frigui W, Ummels R, Damen M, Bottai D, et al. RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection. PLoS Pathog. 2018;14:e1007139 pubmed publisher
García Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al. CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018;9:1970 pubmed publisher
Romano E, Rufo N, Korf H, Mathieu C, Garg A, Agostinis P. BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells. Oncotarget. 2018;9:17631-17644 pubmed publisher
Wong T, Lee C, Su H, Lee C, Wu C, Wang C, et al. A prominent air pollutant, Indeno[1,2,3-cd]pyrene, enhances allergic lung inflammation via aryl hydrocarbon receptor. Sci Rep. 2018;8:5198 pubmed publisher
Dangi A, Zhang L, Zhang X, Luo X. Murine CMV induces type 1 IFN that impairs differentiation of MDSCs critical for transplantation tolerance. Blood Adv. 2018;2:669-680 pubmed publisher
Geslewitz W, Percopo C, Rosenberg H. FACS isolation of live mouse eosinophils at high purity via a protocol that does not target Siglec F. J Immunol Methods. 2018;454:27-31 pubmed publisher
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed publisher
Bai W, Li C, Zhang C, Xu L, Zeng Q, Hu B, et al. Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells. Front Immunol. 2017;8:1919 pubmed publisher
Tsuji R, Ikado K, Fujiwara D. Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production. Int J Mol Sci. 2017;19: pubmed publisher
Turaj A, Hussain K, Cox K, Rose Zerilli M, Testa J, Dahal L, et al. Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment. Cancer Cell. 2017;32:777-791.e6 pubmed publisher
Kim S, Bielawski J, Yang H, Kong Y, Zhou B, Li J. Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination. Glia. 2017;: pubmed publisher
Krzywinska E, Kantari Mimoun C, Kerdiles Y, Sobecki M, Isagawa T, Gotthardt D, et al. Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis. Nat Commun. 2017;8:1597 pubmed publisher
Floudas A, Cluxton C, Fahel J, Khan A, Saunders S, Amu S, et al. Composition of the Schistosoma mansoni worm secretome: Identification of immune modulatory Cyclophilin A. PLoS Negl Trop Dis. 2017;11:e0006012 pubmed publisher
Ano Y, Ikado K, Shindo K, Koizumi H, Fujiwara D. Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells. Sci Rep. 2017;7:13903 pubmed publisher
Wang J, Dai X, Hsu C, Ming C, He Y, Zhang J, et al. Discrimination of the heterogeneity of bone marrow‑derived dendritic cells. Mol Med Rep. 2017;16:6787-6793 pubmed publisher
Liu F, Liu C, Hu X, Shang Y, Wu L. MicroRNA-21: A Positive Regulator for Optimal Production of Type I and Type III Interferon by Plasmacytoid Dendritic Cells. Front Immunol. 2017;8:947 pubmed publisher
Cruz S, Hari A, Qin Z, Couture P, Huang H, Lagace D, et al. Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury. Front Cell Neurosci. 2017;11:201 pubmed publisher
Raj D, Yin Z, Breur M, Doorduin J, Holtman I, Olah M, et al. Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain. Front Mol Neurosci. 2017;10:206 pubmed publisher
McDonald L, Johnson S, Russell D, Young M, LaRue A. Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis. PLoS ONE. 2017;12:e0180724 pubmed publisher
Friedrich C, Mamareli P, Thiemann S, Kruse F, Wang Z, Holzmann B, et al. MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. PLoS Pathog. 2017;13:e1006357 pubmed publisher
Westerterp M, Gautier E, Ganda A, Molusky M, Wang W, Fotakis P, et al. Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. Cell Metab. 2017;25:1294-1304.e6 pubmed publisher
Skopova K, Tomalova B, Kanchev I, Rossmann P, Svedova M, Adkins I, et al. Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis. Infect Immun. 2017;85: pubmed publisher
Hensel J, Khattar V, Ashton R, Lee C, Siegal G, Ponnazhagan S. Location of tumor affects local and distant immune cell type and number. Immun Inflamm Dis. 2017;5:85-94 pubmed publisher
Macpherson K, Sompol P, Kannarkat G, Chang J, Sniffen L, Wildner M, et al. Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice. Neurobiol Dis. 2017;102:81-95 pubmed publisher
Ogawa Y, He H, Mukai S, Imada T, Nakamura S, Su C, et al. Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease. Sci Rep. 2017;7:42195 pubmed publisher
Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed publisher
Kantari Mimoun C, Krzywinska E, Castells M, Milien C, Klose R, Meinecke A, et al. Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice. Oncotarget. 2017;8:15085-15100 pubmed publisher
Wang H, Hu W, Liang Z, Zeng L, Li J, Yan H, et al. Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells. Am J Transl Res. 2016;8:5320-5329 pubmed
Wong T, Chen H, Gau R, Yen J, Suen J. Heme Oxygenase-1-Expressing Dendritic Cells Promote Foxp3+ Regulatory T Cell Differentiation and Induce Less Severe Airway Inflammation in Murine Models. PLoS ONE. 2016;11:e0168919 pubmed publisher
Le Blon D, Guglielmetti C, Hoornaert C, Quarta A, Daans J, Dooley D, et al. Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model. J Neuroinflammation. 2016;13:288 pubmed
Guglielmetti C, Le Blon D, Santermans E, Salas Perdomo A, Daans J, De Vocht N, et al. Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages. Glia. 2016;64:2181-2200 pubmed publisher
Vicetti Miguel R, Quispe Calla N, Pavelko S, Cherpes T. Intravaginal Chlamydia trachomatis Challenge Infection Elicits TH1 and TH17 Immune Responses in Mice That Promote Pathogen Clearance and Genital Tract Damage. PLoS ONE. 2016;11:e0162445 pubmed publisher
Lund A, Wagner M, Fankhauser M, Steinskog E, Broggi M, Spranger S, et al. Lymphatic vessels regulate immune microenvironments in human and murine melanoma. J Clin Invest. 2016;126:3389-402 pubmed publisher
Klein B, Mrowetz H, Thalhamer J, Scheiblhofer S, Weiss R, Aigner L. Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus. Front Cell Neurosci. 2016;10:169 pubmed publisher
Franklin R, Li M. Determining Leukocyte Origins Using Parabiosis in the PyMT Breast Tumor Model. Bio Protoc. 2015;5: pubmed
Raguz J, Jerić I, Niault T, Nowacka J, Kuzet S, Rupp C, et al. Epidermal RAF prevents allergic skin disease. elife. 2016;5: pubmed publisher
McCullough L, Mirza M, Xu Y, Bentivegna K, Steffens E, Ritzel R, et al. Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones. Aging (Albany NY). 2016;8:1432-41 pubmed publisher
Menendez C, Jinkins J, Carr D. Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency. J Immunol. 2016;197:1262-75 pubmed publisher
Zheng H, Zou W, Shen J, Xu L, Wang S, Fu Y, et al. Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth. Stem Cells Transl Med. 2016;5:1216-28 pubmed publisher
Lopes Pinheiro M, Kamermans A, Garcia Vallejo J, Van het Hof B, Wierts L, O Toole T, et al. Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration. elife. 2016;5: pubmed publisher
Vinet J, Vainchtein I, Spano C, Giordano C, Bordini D, Curia G, et al. Microglia are less pro-inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus. Glia. 2016;64:1350-62 pubmed publisher
Cicchini L, Westrich J, Xu T, Vermeer D, Berger J, Clambey E, et al. Suppression of Antitumor Immune Responses by Human Papillomavirus through Epigenetic Downregulation of CXCL14. MBio. 2016;7: pubmed publisher
Hersrud S, Kovács A, Pearce D. Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis. Biochim Biophys Acta. 2016;1862:1324-36 pubmed publisher
Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed publisher
Ivanov S, Scallan J, Kim K, Werth K, Johnson M, Saunders B, et al. CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability. J Clin Invest. 2016;126:1581-91 pubmed publisher
Xu X, Gao Y, Zhai Z, Zhang S, Shan F, Feng J. Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS. Hum Vaccin Immunother. 2016;12:2169-2180 pubmed
Xiao J, Shao L, Shen J, Jiang W, Feng Y, Zheng P, et al. Effects of ketanserin on experimental colitis in mice and macrophage function. Int J Mol Med. 2016;37:659-68 pubmed publisher
Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Yaguchi T, et al. MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model. elife. 2016;5:e09394 pubmed publisher
Grabert K, Michoel T, Karavolos M, Clohisey S, Baillie J, Stevens M, et al. Microglial brain region-dependent diversity and selective regional sensitivities to aging. Nat Neurosci. 2016;19:504-16 pubmed publisher
Connor A, Kelley P, Tempero R. Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis. Lab Invest. 2016;96:270-82 pubmed publisher
Dudek M, Puttur F, Arnold Schrauf C, Kühl A, Holzmann B, Henriques Normark B, et al. Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection. Mucosal Immunol. 2016;9:1288-302 pubmed publisher
Wang B, Merillat S, Vincent M, Huber A, Basrur V, Mangelberger D, et al. Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems. J Biol Chem. 2016;291:3030-42 pubmed publisher
Lagassé H, Anidi I, Craig J, Limjunyawong N, Poupore A, Mitzner W, et al. Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes. J Leukoc Biol. 2016;99:659-71 pubmed publisher
Sawada Y, Honda T, Hanakawa S, Nakamizo S, Murata T, Ueharaguchi Tanada Y, et al. Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses. J Exp Med. 2015;212:1921-30 pubmed publisher
Mimche P, Brady L, Keeton S, Fenne D, King T, Quicke K, et al. Expression of the Receptor Tyrosine Kinase EphB2 on Dendritic Cells Is Modulated by Toll-Like Receptor Ligation but Is Not Required for T Cell Activation. PLoS ONE. 2015;10:e0138835 pubmed publisher
Plaks V, Boldajipour B, Linnemann J, Nguyen N, Kersten K, Wolf Y, et al. Adaptive Immune Regulation of Mammary Postnatal Organogenesis. Dev Cell. 2015;34:493-504 pubmed publisher
Brooks C, Yeung M, Brooks Y, Chen H, Ichimura T, Henderson J, et al. KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation. EMBO J. 2015;34:2441-64 pubmed publisher
DeFalco T, Potter S, Williams A, Waller B, Kan M, Capel B. Macrophages Contribute to the Spermatogonial Niche in the Adult Testis. Cell Rep. 2015;12:1107-19 pubmed publisher
Van den Bossche J, Laoui D, Naessens T, Smits H, Hokke C, Stijlemans B, et al. E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo. Sci Rep. 2015;5:12599 pubmed publisher
Madera L, Greenshields A, Coombs M, Hoskin D. 4T1 Murine Mammary Carcinoma Cells Enhance Macrophage-Mediated Innate Inflammatory Responses. PLoS ONE. 2015;10:e0133385 pubmed publisher
Lee N, Muramatsu S, Chien Y, Liu W, Wang W, Cheng C, et al. Benefits of Neuronal Preferential Systemic Gene Therapy for Neurotransmitter Deficiency. Mol Ther. 2015;23:1572-81 pubmed publisher
Huang L, Kong Y, Wang J, Sun J, Shi Q, Qiu Y. Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway. Mol Med Rep. 2015;12:4187-4195 pubmed publisher
SZETO G, Van Egeren D, Worku H, Sharei A, Alejandro B, Park C, et al. Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines. Sci Rep. 2015;5:10276 pubmed publisher
Mirza M, Ritzel R, Xu Y, McCullough L, Liu F. Sexually dimorphic outcomes and inflammatory responses in hypoxic-ischemic encephalopathy. J Neuroinflammation. 2015;12:32 pubmed publisher
Van Den Ham K, Shio M, Rainone A, Fournier S, Krawczyk C, Olivier M. Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis. PLoS ONE. 2015;10:e0118451 pubmed publisher
Dudek Perić A, Ferreira G, Muchowicz A, Wouters J, Prada N, Martin S, et al. Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin. Cancer Res. 2015;75:1603-14 pubmed publisher
Qin T, Yin Y, Huang L, Yu Q, Yang Q. H9N2 influenza whole inactivated virus combined with polyethyleneimine strongly enhances mucosal and systemic immunity after intranasal immunization in mice. Clin Vaccine Immunol. 2015;22:421-9 pubmed publisher
Ziegler T, Rausch S, Steinfelder S, Klotz C, Hepworth M, Kühl A, et al. A novel regulatory macrophage induced by a helminth molecule instructs IL-10 in CD4+ T cells and protects against mucosal inflammation. J Immunol. 2015;194:1555-64 pubmed publisher
Tsuji R, Koizumi H, Aoki D, Watanabe Y, Sugihara Y, Matsushita Y, et al. Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4). J Biol Chem. 2015;290:4410-21 pubmed publisher
Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, et al. A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice. J Immunol. 2015;194:243-51 pubmed publisher
Lee J, Dang X, Borboa A, Coimbra R, Baird A, Eliceiri B. Thrombin-processed Ecrg4 recruits myeloid cells and induces antitumorigenic inflammation. Neuro Oncol. 2015;17:685-96 pubmed publisher
Kurzejamska E, Johansson J, Jirström K, Prakash V, Ananthaseshan S, Boon L, et al. C/EBPβ expression is an independent predictor of overall survival in breast cancer patients by MHCII/CD4-dependent mechanism of metastasis formation. Oncogenesis. 2014;3:e125 pubmed publisher
Morales D, Monte K, Sun L, Struckhoff J, Agapov E, Holtzman M, et al. Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice. J Virol. 2015;89:337-49 pubmed publisher
Xiao G, Liu I, Cheng C, Chang C, Lee Y, Cheng W, et al. Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy. PLoS ONE. 2014;9:e106538 pubmed publisher
Schulz M, Atay C, Heringer J, Romrig F, Schwitalla S, Aydin B, et al. High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity. Nature. 2014;514:508-12 pubmed publisher
Sparber F, Tripp C, Komenda K, Scheffler J, Clausen B, Huber L, et al. The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGF?1-mediated homeostasis of Langerhans cells. J Invest Dermatol. 2015;135:119-129 pubmed publisher
Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, et al. Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-?. J Exp Med. 2014;211:1393-405 pubmed publisher
Stoolman J, Duncker P, Huber A, Segal B. Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis. J Immunol. 2014;193:564-70 pubmed publisher
Mukonoweshuro B, Brown C, Fisher J, Ingham E. Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells. J Tissue Eng. 2014;5:2041731414534255 pubmed publisher
Assi H, Espinosa J, Suprise S, SOFRONIEW M, Doherty R, Zamler D, et al. Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM. PLoS ONE. 2014;9:e96318 pubmed publisher
O E, Lee Y, Ko E, Kim K, Lee Y, Song J, et al. Roles of major histocompatibility complex class II in inducing protective immune responses to influenza vaccination. J Virol. 2014;88:7764-75 pubmed publisher
Shibata K, Yamada H, Nakamura M, Hatano S, Katsuragi Y, Kominami R, et al. IFN-?-producing and IL-17-producing ?? T cells differentiate at distinct developmental stages in murine fetal thymus. J Immunol. 2014;192:2210-8 pubmed publisher
Westphalen K, Gusarova G, Islam M, Subramanian M, Cohen T, Prince A, et al. Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity. Nature. 2014;506:503-6 pubmed publisher
Bakhru P, Sirisaengtaksin N, Soudani E, Mukherjee S, Khan A, Jagannath C. BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9. Cell Immunol. 2014;287:53-61 pubmed publisher
Ravindran A, Mohammed J, Gunderson A, Cui X, Glick A. Tumor-promoting role of TGF?1 signaling in ultraviolet B-induced skin carcinogenesis is associated with cutaneous inflammation and lymph node migration of dermal dendritic cells. Carcinogenesis. 2014;35:959-66 pubmed publisher
Leyva Castillo J, Hener P, Michea P, Karasuyama H, Chan S, Soumelis V, et al. Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade. Nat Commun. 2013;4:2847 pubmed publisher
Wang S, Wu B, Xue J, Wang M, Chen R, Wang B. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014;10:461-8 pubmed publisher
Berghout J, Langlais D, Radovanovic I, Tam M, MacMicking J, Stevenson M, et al. Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. PLoS Pathog. 2013;9:e1003491 pubmed publisher
Gao Y, Li Z, Hassan N, Mehta P, Burns A, Tang X, et al. NK cells are necessary for recovery of corneal CD11c+ dendritic cells after epithelial abrasion injury. J Leukoc Biol. 2013;94:343-51 pubmed publisher
Vink P, Smout W, Driessen Engels L, de Bruin A, Delsing D, Krajnc Franken M, et al. In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation. PLoS ONE. 2013;8:e57348 pubmed publisher
Dolina J, Sung S, Novobrantseva T, Nguyen T, Hahn Y. Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity. Mol Ther Nucleic Acids. 2013;2:e72 pubmed publisher
Veres T, Voedisch S, Spies E, Valtonen J, Prenzler F, Braun A. Aeroallergen challenge promotes dendritic cell proliferation in the airways. J Immunol. 2013;190:897-903 pubmed publisher
Petersen B, Wolf M, Austermann J, van Lent P, Foell D, Ahlmann M, et al. The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis. EMBO J. 2013;32:100-11 pubmed publisher
Alvarez Breckenridge C, Yu J, Price R, Wojton J, Pradarelli J, Mao H, et al. NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors. Nat Med. 2012;18:1827-34 pubmed publisher
Donat U, Weibel S, Hess M, Stritzker J, Härtl B, Sturm J, et al. Preferential colonization of metastases by oncolytic vaccinia virus strain GLV-1h68 in a human PC-3 prostate cancer model in nude mice. PLoS ONE. 2012;7:e45942 pubmed publisher
He H, Xu J, Warren C, Duan D, Li X, Wu L, et al. Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood. 2012;120:3152-62 pubmed publisher
Lionakis M, Fischer B, Lim J, Swamydas M, Wan W, Richard Lee C, et al. Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis. PLoS Pathog. 2012;8:e1002865 pubmed publisher
Mohammed J, Gunderson A, Khong H, Koubek R, Udey M, Glick A. TGF?1 overexpression by keratinocytes alters skin dendritic cell homeostasis and enhances contact hypersensitivity. J Invest Dermatol. 2013;133:135-43 pubmed publisher
Do J, Valujskikh A, Vignali D, Fairchild R, Min B. Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A. 2012;109:12698-703 pubmed publisher
Lemay C, Rintoul J, Kus A, Paterson J, Garcia V, Falls T, et al. Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine. Mol Ther. 2012;20:1791-9 pubmed publisher
Misharin A, Saber R, Perlman H. Eosinophil contamination of thioglycollate-elicited peritoneal macrophage cultures skews the functional readouts of in vitro assays. J Leukoc Biol. 2012;92:325-31 pubmed publisher
Cheng C, Lian W, Hsiao F, Liu I, Lin S, Lee Y, et al. Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells. PLoS ONE. 2012;7:e36085 pubmed publisher
Maelfait J, Roose K, Bogaert P, Sze M, Saelens X, Pasparakis M, et al. A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection. PLoS Pathog. 2012;8:e1002570 pubmed publisher
Beamer C, Shepherd D. Inhibition of TLR ligand- and interferon gamma-induced murine microglial activation by Panax notoginseng. J Neuroimmune Pharmacol. 2012;7:465-76 pubmed publisher
Lindqvist M, Nookaew I, Brinkenberg I, Samuelson E, Thörn K, Nielsen J, et al. Unraveling molecular signatures of immunostimulatory adjuvants in the female genital tract through systems biology. PLoS ONE. 2011;6:e20448 pubmed publisher
Ciabattini A, Pettini E, Fiorino F, Prota G, Pozzi G, Medaglini D. Distribution of primed T cells and antigen-loaded antigen presenting cells following intranasal immunization in mice. PLoS ONE. 2011;6:e19346 pubmed publisher
Ohue R, Nakamoto M, Kitabatake N, Tani F. Changes in lamina propria dendritic cells on the oral administration of exogenous protein antigens during weaning. Cytotechnology. 2012;64:221-30 pubmed publisher
Stock A, Booth S, Cerundolo V. Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans. J Exp Med. 2011;208:761-73 pubmed publisher
Kinnier C, Martinu T, Gowdy K, Nugent J, Kelly F, Palmer S. Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant. Transpl Immunol. 2011;24:83-93 pubmed publisher
Lionakis M, Lim J, Lee C, Murphy P. Organ-specific innate immune responses in a mouse model of invasive candidiasis. J Innate Immun. 2011;3:180-99 pubmed publisher
Ma L, Mauro C, Cornish G, Chai J, Coe D, Fu H, et al. Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance. Proc Natl Acad Sci U S A. 2010;107:19461-6 pubmed publisher
Giannattasio G, Fujioka D, Xing W, Katz H, Boyce J, Balestrieri B. Group V secretory phospholipase A2 reveals its role in house dust mite-induced allergic pulmonary inflammation by regulation of dendritic cell function. J Immunol. 2010;185:4430-8 pubmed publisher
Nakahara M, Mitsutake N, Sakamoto H, Chen C, Rapoport B, McLachlan S, et al. Enhanced response to mouse thyroid-stimulating hormone (TSH) receptor immunization in TSH receptor-knockout mice. Endocrinology. 2010;151:4047-54 pubmed publisher
Yui M, Feng N, Rothenberg E. Fine-scale staging of T cell lineage commitment in adult mouse thymus. J Immunol. 2010;185:284-93 pubmed publisher
Sugita S, Horie S, Yamada Y, Mochizuki M. Inhibition of B-cell activation by retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2010;51:5783-8 pubmed publisher
Lee H, Mattei L, Steinberg B, Alberts P, Lee Y, Chervonsky A, et al. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 2010;32:227-39 pubmed publisher
Osada M, Jardine L, Misir R, Andl T, Millar S, Pezzano M. DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS ONE. 2010;5:e9062 pubmed publisher
Peters M, Dudziak K, Stiehm M, Bufe A. T-cell polarization depends on concentration of the danger signal used to activate dendritic cells. Immunol Cell Biol. 2010;88:537-44 pubmed publisher
Gaudenzio N, Espagnolle N, Mars L, Liblau R, Valitutti S, Espinosa E. Cell-cell cooperation at the T helper cell/mast cell immunological synapse. Blood. 2009;114:4979-88 pubmed publisher
Choi B, Kim Y, Kwon P, Lee S, Kang S, Kim M, et al. 4-1BB functions as a survival factor in dendritic cells. J Immunol. 2009;182:4107-15 pubmed publisher
Akiyama T, Shimo Y, Yanai H, Qin J, Ohshima D, Maruyama Y, et al. The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity. 2008;29:423-37 pubmed publisher
Pecora N, Fulton S, Reba S, Drage M, Simmons D, Urankar Nagy N, et al. Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection. Cell Immunol. 2009;254:94-104 pubmed publisher
Lee S, Park Y, So T, Kwon B, Cheroutre H, Mittler R, et al. Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells. Nat Immunol. 2008;9:917-26 pubmed publisher
Xin L, Li K, Soong L. Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes. Mol Immunol. 2008;45:3371-82 pubmed publisher
Muralimohan G, Rossi R, Vella A. Recruitment and in situ renewal regulate rapid accumulation of CD11c+ cells in the lung following intranasal superantigen challenge. Int Arch Allergy Immunol. 2008;147:59-73 pubmed publisher
de Haas A, Boddeke H, Biber K. Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS. Glia. 2008;56:888-94 pubmed publisher
Kuwano Y, Prazma C, Yazawa N, Watanabe R, Ishiura N, Kumanogoh A, et al. CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells. Int Immunol. 2007;19:977-92 pubmed
Ehirchiou D, Xiong Y, Xu G, Chen W, Shi Y, Zhang L. CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation. J Exp Med. 2007;204:1519-24 pubmed
Unternaehrer J, Chow A, Pypaert M, Inaba K, Mellman I. The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proc Natl Acad Sci U S A. 2007;104:234-9 pubmed
Idzko M, Hammad H, van Nimwegen M, Kool M, Müller T, Soullie T, et al. Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function. J Clin Invest. 2006;116:2935-44 pubmed
Cuenca J, Martín Sanz P, Alvarez Barrientos A, Bosca L, Goren N. Infiltration of inflammatory cells plays an important role in matrix metalloproteinase expression and activation in the heart during sepsis. Am J Pathol. 2006;169:1567-76 pubmed
Witsch E, Cao H, Fukuyama H, Weigert M. Light chain editing generates polyreactive antibodies in chronic graft-versus-host reaction. J Exp Med. 2006;203:1761-72 pubmed
Gueirard P, Ave P, Balazuc A, Thiberge S, Huerre M, Milon G, et al. Bordetella bronchiseptica persists in the nasal cavities of mice and triggers early delivery of dendritic cells in the lymph nodes draining the lower and upper respiratory tract. Infect Immun. 2003;71:4137-43 pubmed
Li C, Siemasko K, Clark M, Song W. Cooperative interaction of Ig(alpha) and Ig(beta) of the BCR regulates the kinetics and specificity of antigen targeting. Int Immunol. 2002;14:1179-91 pubmed
Bagavant H, Sharp C, Kurth B, Tung K. Induction and immunohistology of autoimmune ovarian disease in cynomolgus macaques (Macaca fascicularis). Am J Pathol. 2002;160:141-9 pubmed
Mendiratta S, Singh N, Bal V, Rath S. Analysis of T-cell hybridomas with an unusual MHC class II-dependent ligand specificity. Immunology. 1996;89:238-44 pubmed
product information
Product Type :
Antibody
Product Name :
MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), FITC, eBioscience™
Catalog # :
11-5321-85
Quantity :
500 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 µg/test
Species :
Mouse
Clone :
M5/114.15.2
Isotype :
IgG2b, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 µg/test
Aliases :
Abeta; AI323765; AI845868; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, A beta chain; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ab; H2-Ab; H2-Ab1; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-iabeta; H2-IE-alpha; histocompatibility 2, class II antigen A, beta 1; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia2; Ia-2; Ia3; Ia-3; Ia4; Ia-4; IAb; I-Ab; I-Abeta; I-Ad; I-Aq; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; I-Ed; I-Ek; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; MHC class 2; MHC class II antigen A beta; MHC class II antigen E alpha; MHC class II H2-IA-beta-psi; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein; response to metastatic cancers 1; Rmcs1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA