product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
EOMES Monoclonal Antibody (WD1928), FITC, eBioscience
catalog :
11-4877-41
quantity :
25 Tests
price :
US 176.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
WD1928
reactivity :
human, pigs
application :
flow cytometry
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s2b
Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed publisher
  • flow cytometry; human; fig 2
Leeansyah E, Svärd J, Dias J, Buggert M, Nyström J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed publisher
Gicobi J, Mao Z, DeFranco G, Hirdler J, Li Y, Vianzon V, et al. Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8+ T cells via ME1 up-regulation. Sci Adv. 2023;9:eadi2414 pubmed publisher
Kourtis N, Wang Q, Wang B, Oswald E, Adler C, Cherravuru S, et al. A single-cell map of dynamic chromatin landscapes of immune cells in renal cell carcinoma. Nat Cancer. 2022;3:885-898 pubmed publisher
McMurray J, von Borstel A, Taher T, Syrimi E, Taylor G, Sharif M, et al. Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program. Cell Rep. 2022;39:110858 pubmed publisher
Kramer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga García R, et al. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. 2021;54:2650-2669.e14 pubmed publisher
Lutter L, Roosenboom B, Brand E, Ter Linde J, Oldenburg B, Van Lochem E, et al. Homeostatic Function and Inflammatory Activation of Ileal CD8+ Tissue-Resident T Cells Is Dependent on Mucosal Location. Cell Mol Gastroenterol Hepatol. 2021;12:1567-1581 pubmed publisher
Sia W, Hey Y, Foo R, Wang L, Leeansyah E. Culture, expansion, and flow-cytometry-based functional analysis of pteropid bat MR1-restricted unconventional T cells. STAR Protoc. 2021;2:100487 pubmed publisher
Hou Q, Xiao Q, Sun X, Ju X, Luo Z. TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a. Sci Adv. 2021;7: pubmed publisher
Pattekar A, Mayer L, Lau C, Liu C, Palko O, Bewtra M, et al. Norovirus-Specific CD8+ T Cell Responses in Human Blood and Tissues. Cell Mol Gastroenterol Hepatol. 2021;11:1267-1289 pubmed publisher
Song M, Pebworth M, Yang X, Abnousi A, Fan C, Wen J, et al. Cell-type-specific 3D epigenomes in the developing human cortex. Nature. 2020;587:644-649 pubmed publisher
Zeis P, Lian M, Fan X, Herman J, Hernandez D, Gentek R, et al. In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. Immunity. 2020;53:775-792.e9 pubmed publisher
Tao L, Farooq M, Gao Y, Zhang L, Niu C, Ajmal I, et al. CD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While Sparing CD19+HLA-C1+ Healthy B Cells. Cancers (Basel). 2020;12: pubmed publisher
Bhattacharya P, Ellegård R, Khalid M, Svanberg C, Govender M, Keita A, et al. Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells. elife. 2020;9: pubmed publisher
Papagno L, Kuse N, Lissina A, Gostick E, Price D, Appay V, et al. The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro. Sci Rep. 2020;10:11620 pubmed publisher
Cederquist G, Tchieu J, Callahan S, Ramnarine K, Ryan S, Zhang C, et al. A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes. Cell Stem Cell. 2020;27:35-49.e6 pubmed publisher
Yoshida T, Ichikawa J, Giuroiu I, Laino A, Hao Y, Krogsgaard M, et al. C reactive protein impairs adaptive immunity in immune cells of patients with melanoma. J Immunother Cancer. 2020;8: pubmed publisher
Kwon M, Kim C, Lee H, Cho H, Kim Y, Lee E, et al. PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors. Clin Cancer Res. 2020;26:1644-1655 pubmed publisher
Katsuyama E, Suárez Fueyo A, Bradley S, Mizui M, Marin A, Mulki L, et al. The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections. Cell Rep. 2020;30:112-123.e4 pubmed publisher
Marquardt N, Kekäläinen E, Chen P, Lourda M, Wilson J, Scharenberg M, et al. Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells. Nat Commun. 2019;10:3841 pubmed publisher
Devorkin L, Pavey N, Carleton G, Comber A, Ho C, Lim J, et al. Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity. Cell Rep. 2019;27:502-513.e5 pubmed publisher
Sagebiel A, Steinert F, Lunemann S, Korner C, Schreurs R, Altfeld M, et al. Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine. Nat Commun. 2019;10:975 pubmed publisher
Paquin Proulx D, Avelino Silva V, Santos B, Silveira Barsotti N, Siroma F, Fernandes Ramos J, et al. MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection. PLoS Negl Trop Dis. 2018;12:e0006154 pubmed publisher
Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, et al. Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors. Immunity. 2017;47:1100-1113.e6 pubmed publisher
Hassouneh F, Lopez Sejas N, Campos C, Sanchez Correa B, Tarazona R, Pera A, et al. Effect of Cytomegalovirus (CMV) and Ageing on T-Bet and Eomes Expression on T-Cell Subsets. Int J Mol Sci. 2017;18: pubmed publisher
Marquardt N, Ivarsson M, Sundström E, Akesson E, Martini E, Eidsmo L, et al. Fetal CD103+ IL-17-Producing Group 3 Innate Lymphoid Cells Represent the Dominant Lymphocyte Subset in Human Amniotic Fluid. J Immunol. 2016;197:3069-3075 pubmed
Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson M, Kekäläinen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol. 2015;194:2467-71 pubmed publisher
Narayanan S, Silva R, Peruzzi G, Alvarez Y, Simhadri V, DeBell K, et al. Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin. PLoS ONE. 2010;5:e10636 pubmed publisher
product information
Product Type :
Antibody
Product Name :
EOMES Monoclonal Antibody (WD1928), FITC, eBioscience
Catalog # :
11-4877-41
Quantity :
25 Tests
Price :
US 176.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human, Porcine
Applications :
Flow Cytometry: 5 uL (0.06 ug)/test
Species :
Human, Porcine
Clone :
WD1928
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.06 ug)/test
Aliases :
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA