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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IgA Monoclonal Antibody (mA-6E1), FITC, eBioscience
catalog :
11-4204-83
quantity :
200 ug
price :
US 392.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
mA-6E1
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 26
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 3b
Robak O, Heimesaat M, Kruglov A, Prepens S, Ninnemann J, Gutbier B, et al. Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia. J Clin Invest. 2018;128:3535-3545 pubmed publisher
Rivera C, Zhou Y, Chupp D, Yan H, Fisher A, Simon R, et al. Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells. Sci Adv. 2023;9:eade8928 pubmed publisher
Zhang W, Yuan Y, Li X, Luo J, Zhou Z, Yu L, et al. Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymphocytes. Front Immunol. 2022;13:900963 pubmed publisher
Xu Y, Zhou H, Post G, Zan H, Casali P. Rad52 mediates class-switch DNA recombination to IgD. Nat Commun. 2022;13:980 pubmed publisher
Mirman Z, Sasi N, King A, Chapman J, de Lange T. 53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis. Nat Cell Biol. 2022;24:51-61 pubmed publisher
Tan J, Cho H, Pholcharee T, Pereira L, Doumbo S, Doumtabe D, et al. Functional human IgA targets a conserved site on malaria sporozoites. Sci Transl Med. 2021;13: pubmed publisher
Platt J, de Mattos Barbosa M, Huynh D, Lefferts A, Katta J, Kharas C, et al. TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA. JCI Insight. 2021;6: pubmed publisher
Singh S, Bastos Amador P, Thompson J, Truglio M, Yilmaz B, Cardoso S, et al. Glycan-based shaping of the microbiota during primate evolution. elife. 2021;10: pubmed publisher
Prados A, Onder L, Cheng H, Mörbe U, Lütge M, Gil Cruz C, et al. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol. 2021;22:510-519 pubmed publisher
Francica P, Mutlu M, Blomen V, Oliveira C, Nowicka Z, Trenner A, et al. Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining. Cell Rep. 2020;32:108068 pubmed publisher
Yang C, Mogno I, Contijoch E, Borgerding J, Aggarwala V, Li Z, et al. Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation. Cell Host Microbe. 2020;27:467-475.e6 pubmed publisher
Tran H, Ley R, Gewirtz A, Chassaing B. Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases. Nat Commun. 2019;10:5650 pubmed publisher
Schoeler K, Jakic B, Heppke J, Soratroi C, Aufschnaiter A, Hermann Kleiter N, et al. CHK1 dosage in germinal center B cells controls humoral immunity. Cell Death Differ. 2019;: pubmed publisher
Ramakrishnan S, Zhang H, Ma X, Jung I, Schwartz A, Triner D, et al. Intestinal non-canonical NFκB signaling shapes the local and systemic immune response. Nat Commun. 2019;10:660 pubmed publisher
Martínez López M, Iborra S, Conde Garrosa R, Mastrangelo A, Danne C, Mann E, et al. Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity. Immunity. 2019;50:446-461.e9 pubmed publisher
Grizotte Lake M, Zhong G, Duncan K, Kirkwood J, Iyer N, Smolenski I, et al. Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis. Immunity. 2018;49:1103-1115.e6 pubmed publisher
Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed publisher
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
Ghezraoui H, Oliveira C, Becker J, Bilham K, Moralli D, Anzilotti C, et al. 53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ. Nature. 2018;560:122-127 pubmed publisher
Tsuji R, Ikado K, Fujiwara D. Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production. Int J Mol Sci. 2017;19: pubmed publisher
Bemark M, Hazanov H, Strömberg A, Komban R, Holmqvist J, Köster S, et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat Commun. 2016;7:12698 pubmed publisher
de Winde C, Veenbergen S, Young K, Xu Monette Z, Wang X, Xia Y, et al. Tetraspanin CD37 protects against the development of B cell lymphoma. J Clin Invest. 2016;126:653-66 pubmed publisher
Kim M, Kim T. IgA+ plasma cells in murine intestinal lamina propria as a positive regulator of Treg differentiation. J Leukoc Biol. 2014;95:461-9 pubmed publisher
Pierre J, Heneghan A, Wang X, Roenneburg D, Groblewski G, Kudsk K. Bombesin improves adaptive immunity of the salivary gland during parenteral nutrition. JPEN J Parenter Enteral Nutr. 2015;39:190-9 pubmed publisher
Kim M, Kim T. R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells. Cytometry A. 2013;83:452-60 pubmed publisher
Kotani A, Kakazu N, Tsuruyama T, Okazaki I, Muramatsu M, Kinoshita K, et al. Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice. Proc Natl Acad Sci U S A. 2007;104:1616-20 pubmed
product information
Product Type :
Antibody
Product Name :
IgA Monoclonal Antibody (mA-6E1), FITC, eBioscience
Catalog # :
11-4204-83
Quantity :
200 ug
Price :
US 392.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 1 ug/test
Species :
Mouse
Clone :
mA-6E1
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Mouse IgA is an immunoglobulin A antibody that is produced by B cells in response to an antigen. It is a crucial component of the mucosal immune system, which protects the body from pathogens that enter through mucosal surfaces such as the respiratory, gastrointestinal, and urogenital tracts. Mouse IgA is composed of two heavy chains and two light chains, and it is the most abundant immunoglobulin in mucosal secretions. It plays a vital role in neutralizing pathogens and preventing their attachment to mucosal surfaces. Mouse IgA is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/test
Aliases :
IgA; Igh-2; Igha; immunoglobulin heavy constant alpha; ImmunoglobulinA
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA