IgA Monoclonal Antibody (mA-6E1), FITC, eBioscience | Invitrogen 11-4204-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IgA Monoclonal Antibody (mA-6E1), FITC, eBioscience

catalog :

11-4204-81

quantity :

50 ug

price :

US 133.00

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

mA-6E1

reactivity :

mouse

application :

flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 2f	Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
flow cytometry; mouse; loading ...; fig 3b	Robak O, Heimesaat M, Kruglov A, Prepens S, Ninnemann J, Gutbier B, et al. Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia. J Clin Invest. 2018;128:3535-3545 pubmed publisher
	Rivera C, Zhou Y, Chupp D, Yan H, Fisher A, Simon R, et al. Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells. Sci Adv. 2023;9:eade8928 pubmed publisher
	Zhang W, Yuan Y, Li X, Luo J, Zhou Z, Yu L, et al. Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymphocytes. Front Immunol. 2022;13:900963 pubmed publisher
	Xu Y, Zhou H, Post G, Zan H, Casali P. Rad52 mediates class-switch DNA recombination to IgD. Nat Commun. 2022;13:980 pubmed publisher
	Mirman Z, Sasi N, King A, Chapman J, de Lange T. 53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis. Nat Cell Biol. 2022;24:51-61 pubmed publisher
	Tan J, Cho H, Pholcharee T, Pereira L, Doumbo S, Doumtabe D, et al. Functional human IgA targets a conserved site on malaria sporozoites. Sci Transl Med. 2021;13: pubmed publisher
	Platt J, de Mattos Barbosa M, Huynh D, Lefferts A, Katta J, Kharas C, et al. TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA. JCI Insight. 2021;6: pubmed publisher
	Singh S, Bastos Amador P, Thompson J, Truglio M, Yilmaz B, Cardoso S, et al. Glycan-based shaping of the microbiota during primate evolution. elife. 2021;10: pubmed publisher
	Prados A, Onder L, Cheng H, Mörbe U, Lütge M, Gil Cruz C, et al. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol. 2021;22:510-519 pubmed publisher
	Francica P, Mutlu M, Blomen V, Oliveira C, Nowicka Z, Trenner A, et al. Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining. Cell Rep. 2020;32:108068 pubmed publisher
	Yang C, Mogno I, Contijoch E, Borgerding J, Aggarwala V, Li Z, et al. Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation. Cell Host Microbe. 2020;27:467-475.e6 pubmed publisher
	Tran H, Ley R, Gewirtz A, Chassaing B. Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases. Nat Commun. 2019;10:5650 pubmed publisher
	Schoeler K, Jakic B, Heppke J, Soratroi C, Aufschnaiter A, Hermann Kleiter N, et al. CHK1 dosage in germinal center B cells controls humoral immunity. Cell Death Differ. 2019;: pubmed publisher
	Ramakrishnan S, Zhang H, Ma X, Jung I, Schwartz A, Triner D, et al. Intestinal non-canonical NFκB signaling shapes the local and systemic immune response. Nat Commun. 2019;10:660 pubmed publisher
	Martínez López M, Iborra S, Conde Garrosa R, Mastrangelo A, Danne C, Mann E, et al. Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity. Immunity. 2019;50:446-461.e9 pubmed publisher
	Grizotte Lake M, Zhong G, Duncan K, Kirkwood J, Iyer N, Smolenski I, et al. Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis. Immunity. 2018;49:1103-1115.e6 pubmed publisher
	Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed publisher
	Ghezraoui H, Oliveira C, Becker J, Bilham K, Moralli D, Anzilotti C, et al. 53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ. Nature. 2018;560:122-127 pubmed publisher
	Tsuji R, Ikado K, Fujiwara D. Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production. Int J Mol Sci. 2017;19: pubmed publisher
	Bemark M, Hazanov H, Strömberg A, Komban R, Holmqvist J, Köster S, et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat Commun. 2016;7:12698 pubmed publisher
	de Winde C, Veenbergen S, Young K, Xu Monette Z, Wang X, Xia Y, et al. Tetraspanin CD37 protects against the development of B cell lymphoma. J Clin Invest. 2016;126:653-66 pubmed publisher
	Kim M, Kim T. IgA+ plasma cells in murine intestinal lamina propria as a positive regulator of Treg differentiation. J Leukoc Biol. 2014;95:461-9 pubmed publisher
	Pierre J, Heneghan A, Wang X, Roenneburg D, Groblewski G, Kudsk K. Bombesin improves adaptive immunity of the salivary gland during parenteral nutrition. JPEN J Parenter Enteral Nutr. 2015;39:190-9 pubmed publisher
	Kim M, Kim T. R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells. Cytometry A. 2013;83:452-60 pubmed publisher
	Kotani A, Kakazu N, Tsuruyama T, Okazaki I, Muramatsu M, Kinoshita K, et al. Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice. Proc Natl Acad Sci U S A. 2007;104:1616-20 pubmed

product information

Product Type :

Antibody

Product Name :

IgA Monoclonal Antibody (mA-6E1), FITC, eBioscience

Catalog # :

11-4204-81

Quantity :

50 ug

Price :

US 133.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 ug/test

Species :

Mouse

Clone :

mA-6E1

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Mouse IgA is an immunoglobulin A antibody that is produced by B cells in response to an antigen. It is a crucial component of the mucosal immune system, which protects the body from pathogens that enter through mucosal surfaces such as the respiratory, gastrointestinal, and urogenital tracts. Mouse IgA is composed of two heavy chains and two light chains, and it is the most abundant immunoglobulin in mucosal secretions. It plays a vital role in neutralizing pathogens and preventing their attachment to mucosal surfaces. Mouse IgA is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test

Aliases :

IgA; Igh-2; Igha; immunoglobulin heavy constant alpha; ImmunoglobulinA

more info or order :

Invitrogen product webpage