CD150 Monoclonal Antibody (A12 (7D4)), FITC, eBioscience | Invitrogen 11-1509-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD150 Monoclonal Antibody (A12 (7D4)), FITC, eBioscience

catalog :

11-1509-42

quantity :

100 Tests

price :

US 305.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

A12 (7D4)

The same clone is also sold as:

BioLegend: 306313, 306317, 306306, 306308, 306302, 306318, 306307, 306321, 306312, 306319, 306315

reactivity :

human

application :

flow cytometry

citations: 2

Reference
Larochelle A, Savona M, Wiggins M, Anderson S, Ichwan B, Keyvanfar K, et al. Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers. Blood. 2011;117:1550-4 pubmed publisher
Cocks B, Chang C, Carballido J, Yssel H, de Vries J, Aversa G. A novel receptor involved in T-cell activation. Nature. 1995;376:260-3 pubmed

product information

Product Type :

Antibody

Product Name :

CD150 Monoclonal Antibody (A12 (7D4)), FITC, eBioscience

Catalog # :

11-1509-42

Quantity :

100 Tests

Price :

US 305.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (1 ug)/test

Species :

Human

Clone :

A12 (7D4)

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (1 ug)/test

Aliases :

4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; Slamf1