This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD116 Monoclonal Antibody (4H1), FITC, eBioscience™
catalog :
11-1169-41
quantity :
25Tests
price :
US 86.5
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
4H1
reactivity :
human
application :
immunocytochemistry, flow cytometry
citations: 1
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Hiyoshi M, Suzu S, Yoshidomi Y, Hassan R, Harada H, Sakashita N, et al. Interaction between Hck and HIV-1 Nef negatively regulates cell surface expression of M-CSF receptor. Blood. 2008;111:243-50 pubmed
product information
Product Type :
Antibody
Product Name :
CD116 Monoclonal Antibody (4H1), FITC, eBioscience™
Catalog # :
11-1169-41
Quantity :
25Tests
Price :
US 86.5
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (1 µg)/test, Immunocytochemistry: 1:100, Immunofluorescence: 1:100
Species :
Human
Clone :
4H1
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common beta subunit. The a subunits are low affinity ligand binding proteins while the beta subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct beta subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine beta-subunits are 91% homologous at the amino acid level but only 56% homologous to the human beta subunit. Although neither the murine nor the human beta subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (1 µg)/test, Immunocytochemistry: 1:100, Immunofluorescence: 1:100
Aliases :
CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, MGC3848, MGC4838
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA