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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD71 (Transferrin Receptor) Monoclonal Antibody (R17217 (RI7 217.1.4)), FITC, eBioscience
catalog :
11-0711-85
quantity :
500 ug
price :
US 387.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
R17217 (RI7 217.1.4)
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 42
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Costa D, Principi E, Lazzarini E, Descalzi F, Cancedda R, Castagnola P, et al. LCN2 overexpression in bone enhances the hematopoietic compartment via modulation of the bone marrow microenvironment. J Cell Physiol. 2017;232:3077-3087 pubmed publisher
  • flow cytometry; mouse
Ghazaryan S, Sy C, Hu T, An X, Mohandas N, Fu H, et al. Inactivation of Rb and E2f8 synergizes to trigger stressed DNA replication during erythroid terminal differentiation. Mol Cell Biol. 2014;34:2833-47 pubmed publisher
  • flow cytometry; mouse
Ripich T, Jessberger R. SWAP-70 regulates erythropoiesis by controlling ?4 integrin. Haematologica. 2011;96:1743-52 pubmed publisher
Hosaka K, Wang C, Zhang S, Lv X, Seki T, Zhang Y, et al. Perivascular localized cells commit erythropoiesis in PDGF-B-expressing solid tumors. Cancer Commun (Lond). 2023;43:637-660 pubmed publisher
Díaz Vegas A, Norris D, Jall Rogg S, Cooke K, Conway O, Shun Shion A, et al. A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology. Life Sci Alliance. 2023;6: pubmed publisher
Meacham C, Jeffery E, Burgess R, Sivakumar C, Arora M, Stanley A, et al. Adiponectin receptors sustain haematopoietic stem cells throughout adulthood by protecting them from inflammation. Nat Cell Biol. 2022;24:697-707 pubmed publisher
Deshycka R, Sudaryo V, Huang N, Xie Y, Smeding L, Choi M, et al. Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity. PLoS ONE. 2021;16:e0259353 pubmed publisher
Ju M, Shin K, Lee J, Khim K, A Lee E, Ra J, et al. NSMF promotes the replication stress-induced DNA damage response for genome maintenance. Nucleic Acids Res. 2021;49:5605-5622 pubmed publisher
Huang J, Zhou Q, Gao M, Nowsheen S, Zhao F, Kim W, et al. Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. Mol Cell. 2020;79:824-835.e5 pubmed publisher
Egusquiza R, Ambrosio M, Wang S, Kay K, Zhang C, Lehmler H, et al. Evaluating the Role of the Steroid and Xenobiotic Receptor (SXR/PXR) in PCB-153 Metabolism and Protection against Associated Adverse Effects during Perinatal and Chronic Exposure in Mice. Environ Health Perspect. 2020;128:47011 pubmed publisher
Wang F, Zhu J, Zheng J, Duan W, Zhou Z. miR‑210 enhances mesenchymal stem cell‑modulated neural precursor cell migration. Mol Med Rep. 2020;21:2405-2414 pubmed publisher
Hidalgo San Jose L, Sunshine M, Dillingham C, Chua B, Krutá M, Hong Y, et al. Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. Cell Rep. 2020;30:69-80.e6 pubmed publisher
Cheng Y, Luo H, Izzo F, Pickering B, Nguyen D, Myers R, et al. m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. Cell Rep. 2019;28:1703-1716.e6 pubmed publisher
Nandakumar S, McFarland S, Mateyka L, Lareau C, Ulirsch J, Ludwig L, et al. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. elife. 2019;8: pubmed publisher
Zhao B, Mei Y, Cao L, Zhang J, Sumagin R, Yang J, et al. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms. J Clin Invest. 2018;128:125-140 pubmed publisher
Brown J, Yonekubo Y, Hanson N, Sastre Perona A, Basin A, Rytlewski J, et al. TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. Cell Stem Cell. 2017;21:650-664.e8 pubmed publisher
Huang N, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, et al. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nat Commun. 2017;8:423 pubmed publisher
Pasricha S, Lim P, Duarte T, Casu C, Oosterhuis D, Mleczko Sanecka K, et al. Hepcidin is regulated by promoter-associated histone acetylation and HDAC3. Nat Commun. 2017;8:403 pubmed publisher
Laroque A, Min oo G, Tam M, Ponka P, Stevenson M, Gros P. The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria. PLoS ONE. 2017;12:e0177818 pubmed publisher
Zhang Y, Zhang J, An W, Wan Y, Ma S, Yin J, et al. Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation. Nucleic Acids Res. 2017;45:657-671 pubmed publisher
Jonas B, Johnson C, Gratzinger D, Majeti R. Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity. PLoS ONE. 2016;11:e0159189 pubmed publisher
Hu Y, Zhang Y, Tian K, Xun C, Wang S, Lv D. Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro. Mol Med Rep. 2016;13:49-58 pubmed publisher
Ghanem L, Kromer A, Silverman I, Chatterji P, Traxler E, Penzo Méndez A, et al. The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Mol Cell Biol. 2016;36:304-19 pubmed publisher
Liang R, Camprecios G, Kou Y, McGrath K, Nowak R, Catherman S, et al. A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis. PLoS Genet. 2015;11:e1005526 pubmed publisher
Lee H, Gao X, Barrasa M, Li H, Elmes R, Peters L, et al. PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. Nature. 2015;522:474-7 pubmed publisher
Ludwig L, Cho H, Wakabayashi A, Eng J, Ulirsch J, Fleming M, et al. Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis. Am J Hematol. 2015;90:386-91 pubmed publisher
Cho J, Seo J, Lim C, Yang L, Shiratsuchi T, Lee M, et al. Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis. Cell Death Differ. 2015;22:1437-50 pubmed publisher
Salmond R, Brownlie R, Morrison V, Zamoyska R. The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals. Nat Immunol. 2014;15:875-883 pubmed publisher
Franke K, Kalucka J, Mamlouk S, Singh R, Muschter A, Weidemann A, et al. HIF-1? is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2?-induced excessive erythropoiesis. Blood. 2013;121:1436-45 pubmed publisher
Bai X, Trowbridge J, Riley E, Lee J, DiBiase A, KAARTINEN V, et al. TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes. Dev Biol. 2013;373:422-30 pubmed publisher
Wartman L, Welch J, Uy G, Klco J, Lamprecht T, Varghese N, et al. Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice. PLoS ONE. 2012;7:e46529 pubmed publisher
Vemula S, Shi J, Mali R, Ma P, Liu Y, Hanneman P, et al. ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53. Blood. 2012;120:2868-78 pubmed publisher
Yemisci M, Gursoy Ozdemir Y, Caban S, Bodur E, Capan Y, Dalkara T. Transport of a caspase inhibitor across the blood-brain barrier by chitosan nanoparticles. Methods Enzymol. 2012;508:253-69 pubmed publisher
Hu T, Ghazaryan S, Sy C, Wiedmeyer C, Chang V, Wu L. Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia. Blood. 2012;119:4532-42 pubmed publisher
Caban S, Capan Y, Couvreur P, Dalkara T. Preparation and characterization of biocompatible chitosan nanoparticles for targeted brain delivery of peptides. Methods Mol Biol. 2012;846:321-32 pubmed publisher
Li H, Liu W, Michalak M. Enhanced clathrin-dependent endocytosis in the absence of calnexin. PLoS ONE. 2011;6:e21678 pubmed publisher
Libregts S, Gutierrez L, de Bruin A, Wensveen F, Papadopoulos P, van Ijcken W, et al. Chronic IFN-? production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis. Blood. 2011;118:2578-88 pubmed publisher
Wilhelm B, Briau M, Austin P, Faubert A, Boucher G, Chagnon P, et al. RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity. Blood. 2011;117:e27-38 pubmed publisher
Freter R, Osawa M, Nishikawa S. Adult stem cells exhibit global suppression of RNA polymerase II serine-2 phosphorylation. Stem Cells. 2010;28:1571-80 pubmed publisher
Trowbridge J, Snow J, Kim J, Orkin S. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell. 2009;5:442-9 pubmed publisher
Lyons P, Peck G, Kettenbach A, Gerber S, Roudaia L, Lienhard G. Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes. Biosci Rep. 2009;29:229-35 pubmed publisher
Chappaz S, Flueck L, Farr A, Rolink A, Finke D. Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice. Blood. 2007;110:3862-70 pubmed
product information
Product Type :
Antibody
Product Name :
CD71 (Transferrin Receptor) Monoclonal Antibody (R17217 (RI7 217.1.4)), FITC, eBioscience
Catalog # :
11-0711-85
Quantity :
500 ug
Price :
US 387.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Mouse
Clone :
R17217 (RI7 217.1.4)
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA