CD68 Monoclonal Antibody (eBioY1/82A (Y1/82A)), FITC, eBioscience™ | Invitrogen 11-0689-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (eBioY1/82A (Y1/82A)), FITC, eBioscience™

catalog :

11-0689-42

quantity :

100 Tests

price :

221 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

eBioY1/82A (Y1/82A)

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1d immunocytochemistry; human; loading ...; fig 1c	Tsai C, Lin Y, Huang C, Shih C, Tsai Y, Tsao N, et al. Thrombomodulin regulates monocye differentiation via PKC? and ERK1/2 pathway in vitro and in atherosclerotic artery. Sci Rep. 2016;6:38421 pubmed publisher
flow cytometry; human	Chalan P, Bijzet J, Huitema M, Kroesen B, Brouwer E, Boots A. Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis. PLoS ONE. 2015;10:e0132436 pubmed publisher
	Izadi D, Layton T, Williams L, McCann F, Cabrita M, Espirito Santo A, et al. Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis. Sci Adv. 2019;5:eaay0370 pubmed publisher
	Zhao X, Qu J, Liu X, Wang J, Ma X, Zhao X, et al. Baicalein suppress EMT of breast cancer by mediating tumor-associated macrophages polarization. Am J Cancer Res. 2018;8:1528-1540 pubmed
	Jannasch M, Gaetzner S, Weigel T, Walles H, Schmitz T, Hansmann J. A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial. Sci Rep. 2017;7:1689 pubmed publisher
	Luo Y, Duan H, Qian Y, Feng L, Wu Z, Wang F, et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res. 2017;27:352-372 pubmed publisher
	Garcia Mesa Y, Jay T, Checkley M, Luttge B, Dobrowolski C, Valadkhan S, et al. Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system. J Neurovirol. 2017;23:47-66 pubmed publisher
	Jannasch M, Weigel T, Engelhardt L, Wiezoreck J, Gaetzner S, Walles H, et al. In vitro chemotaxis and tissue remodeling assays quantitatively characterize foreign body reaction. ALTEX. 2017;34:253-266 pubmed publisher
	Broeren M, de Vries M, Bennink M, Arntz O, van Lent P, van der Kraan P, et al. Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane. Arthritis Res Ther. 2016;18:186 pubmed publisher
	Zhong Y, Yi C. MicroRNA-720 suppresses M2 macrophage polarization by targeting GATA3. Biosci Rep. 2016;36: pubmed publisher
	He L, Marneros A. Doxycycline inhibits polarization of macrophages to the proangiogenic M2-type and subsequent neovascularization. J Biol Chem. 2014;289:8019-28 pubmed publisher
	VanSaun M, Mendonsa A, Lee Gorden D. Hepatocellular proliferation correlates with inflammatory cell and cytokine changes in a murine model of nonalchoholic fatty liver disease. PLoS ONE. 2013;8:e73054 pubmed publisher
	Strobl H, Scheinecker C, Csmarits B, Majdic O, Knapp W. Flow cytometric analysis of intracellular CD68 molecule expression in normal and malignant haemopoiesis. Br J Haematol. 1995;90:774-82 pubmed
	Davey F, Cordell J, Erber W, Pulford K, Gatter K, Mason D. Monoclonal antibody (Y1/82A) with specificity towards peripheral blood monocytes and tissue macrophages. J Clin Pathol. 1988;41:753-8 pubmed

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (eBioY1/82A (Y1/82A)), FITC, eBioscience™

Catalog # :

11-0689-42

Quantity :

100 Tests

Price :

221 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test, Immunocytochemistry: 0.125 µg/mL, Immunofluorescence: 0.125 µg/mL

Species :

Human

Clone :

eBioY1/82A (Y1/82A)

Isotype :

IgG2b, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test, Immunocytochemistry: 0.125 µg/mL, Immunofluorescence: 0.125 µg/mL

Aliases :

CD68; CD68 antigen; CD68 molecule; Gp110; LAMP4; macrophage antigen CD68; macrosialin; SCARD1; scavenger receptor class D, member 1; similar to CD68 antigen

more info or order :

Invitrogen product webpage