CD65 Monoclonal Antibody (VIM8), FITC, eBioscience | Invitrogen 11-0659-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD65 Monoclonal Antibody (VIM8), FITC, eBioscience

catalog :

11-0659-42

quantity :

100 Tests

price :

US 397.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

VIM8

application :

flow cytometry

citations: 4

Reference
Romanski A, Bug G. Establishment and Characterization of Long-Term Cultures Derived from Primary Acute Myeloid Leukemia Cells for HDAC Inhibitor Research. Methods Mol Biol. 2017;1510:127-148 pubmed
Paietta E, Neuberg D, Bennett J, Dewald G, Rowe J, Cassileth P, et al. Low expression of the myeloid differentiation antigen CD65s, a feature of poorly differentiated AML in older adults: study of 711 patients enrolled in ECOG trials. Leukemia. 2003;17:1544-50 pubmed
Noguchi M, Sato N, Sugimori H, Mori K, Oshimi K. A minor E-selectin ligand, CD65, is critical for extravascular infiltration of acute myeloid leukemia cells. Leuk Res. 2001;25:847-53 pubmed
Kniep B, Peter Katalinic J, Muthing J, Majdic O, Pickl W, Knapp W. The CDw65 monoclonal antibodies VIM-8 and VIM-11 bind to the neutral glycolipid V3FucnLc8Cer. J Biochem. 1996;119:456-62 pubmed

product information

Product Type :

Antibody

Product Name :

CD65 Monoclonal Antibody (VIM8), FITC, eBioscience

Catalog # :

11-0659-42

Quantity :

100 Tests

Price :

US 397.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Human

Clone :

VIM8

Isotype :

IgM

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

This type 2 fucosylated carbohydrate antigen is expressed on the surface of all myeloid cells during development. Moreover, CD65 is expressed highly on granulocytes and weakly on monocytes in peripheral blood. CD65 has been reported to be a ligand for CD62E (E-Selectin). However, the sialylated form of CD65 (designated CD65s) can be used as a marker for acute myeloid leukemia (AML) as its expression increases as CD34 decreases. Finally, CD65 is important for extravascular infiltration of AML cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

Fucoganglioside Type 2; Fucoganglioside Type II