CD62P (P-Selectin) Monoclonal Antibody (AK-4), FITC, eBioscience | Invitrogen 11-0628-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD62P (P-Selectin) Monoclonal Antibody (AK-4), FITC, eBioscience

catalog :

11-0628-42

quantity :

100 Tests

price :

US 258.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

AK-4

The same clone is also sold as:

Exbio: 1F-667-T025, T8-667-T100, 1P-667-T025, 1A-667-T100, 12-667-C100, 1B-667-C025, 11-667-C025, 1B-667-C100, T8-667-T025, 1A-667-T025, 1P-667-T100, 1F-667-T100, 11-667-C100
BioLegend: 304914, 304931, 304920, 304943, 304938, 304933, 304926, 304947, 304932, 304941, 304945, 304937, 304919, 260362, 304944, 304908, 304939, 304936, 304904, 304951, 304948, 304942, 304921, 304918, 304928, 304906, 304910, 304930, 304925, 986404, 260364, 304922, 304927, 304905, 304916, 304940, 304949, 304929, 304935, 304902, 304924, 986402, 304903
OriGene: AM26020AC-N, AM26020PU-N, AM26020LE-N, AM26020RP-N, AM26020FC-N, AM26020BT-N
BD Biosciences: 551345, 550888, 555522, 555523, 555524
Santa Cruz Biotechnology: sc-19996 L, sc-19996

reactivity :

human

application :

flow cytometry

citations: 6

Reference
Wang X, Zhang B, Lu X, Wang P. Efficacy of different hemodialysis methods on dendritic cell marker CD40 and CD80 and platelet activation marker CD62P and P10 in patients with chronic renal failure. J Clin Lab Anal. 2019;33:e22713 pubmed publisher
Jia Y, Zhang S, Miao L, Wang J, Jin Z, Gu B, et al. Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620. Oncol Rep. 2015;33:2681-8 pubmed publisher
Maione F, Cicala C, Liverani E, Mascolo N, Perretti M, D Acquisto F. IL-17A increases ADP-induced platelet aggregation. Biochem Biophys Res Commun. 2011;408:658-62 pubmed publisher
Kapp K, Maul J, Hostmann A, Mundt P, Preiss J, Wenzel A, et al. Modulation of systemic antigen-specific immune responses by oral antigen in humans. Eur J Immunol. 2010;40:3128-37 pubmed publisher
Chen W, Evans E, McEver R, Zhu C. Monitoring receptor-ligand interactions between surfaces by thermal fluctuations. Biophys J. 2008;94:694-701 pubmed
Sinauridze E, Kireev D, Popenko N, Pichugin A, Panteleev M, Krymskaya O, et al. Platelet microparticle membranes have 50- to 100-fold higher specific procoagulant activity than activated platelets. Thromb Haemost. 2007;97:425-34 pubmed

product information

Product Type :

Antibody

Product Name :

CD62P (P-Selectin) Monoclonal Antibody (AK-4), FITC, eBioscience

Catalog # :

11-0628-42

Quantity :

100 Tests

Price :

US 258.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (1 ug)/test

Species :

Human

Clone :

AK-4

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate. P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes. P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, thrombosis and tissue destruction. Clinically, P-selectin is used to distinguish heparin induced thrombocytopenia with and without thrombosis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (1 ug)/test

Aliases :

CD62; CD62 antigen-like family member P; CD62P; CD62P antigen; CD62P; CD62 homolog; FLJ45155; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; Grmp; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; PSELECT; P-selectin; P-selectin precursor; RP1-86F14.2; selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); selectin, platelet; Selp