CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), FITC, eBioscience | Invitrogen 11-0541-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), FITC, eBioscience

catalog :

11-0541-81

quantity :

50 ug

price :

US 105.00

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

YN1/1.7.4

reactivity :

human, mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200; fig st1	Brinkman C, Iwami D, Hritzo M, Xiong Y, Ahmad S, Simon T, et al. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nat Commun. 2016;7:12021 pubmed publisher
flow cytometry; human; fig 6	Zhang F, Marcus W, Goyal N, Selvaraj P, Springer T, Zhu C. Two-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domain. J Biol Chem. 2005;280:42207-18 pubmed
	van Elsas M, Labrie C, Etzerodt A, Charoentong P, van Stigt Thans J, van Hall T, et al. Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy. J Immunother Cancer. 2023;11: pubmed publisher
	Mar xed n Rubio J, Peltier Heap R, Due xf1 as M, Heunis T, Dannoura A, Inns J, et al. A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia. J Med Chem. 2022;65:12014-12030 pubmed publisher
	Chong D, Rebeyrol C, José R, Williams A, Brown J, Scotton C, et al. ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo. Front Immunol. 2021;12:691957 pubmed publisher
	Kim H, Park J, Park J, Yasmin F, Kim C, Oh S, et al. Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy. J Hematol Oncol. 2021;14:43 pubmed publisher
	Zhong H, Lin H, Pang Q, Zhuang J, Liu X, Li X, et al. Macrophage ICAM-1 functions as a regulator of phagocytosis in LPS induced endotoxemia. Inflamm Res. 2021;70:193-203 pubmed publisher
	Li W, Chen S, Luo Y, Xia Y, Ma Q, Yao Q, et al. Interaction between ICAM1 in endothelial cells and LFA1 in T cells during the pathogenesis of experimental Parkinson's disease. Exp Ther Med. 2020;20:1021-1029 pubmed publisher
	Kanitz A, Syed A, Kaji K, Zavolan M. Conserved regulation of RNA processing in somatic cell reprogramming. BMC Genomics. 2019;20:100 pubmed publisher
	Deloch L, Rückert M, Fietkau R, Frey B, Gaipl U. Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints. Int J Mol Sci. 2018;19: pubmed publisher
	Pincha N, Hajam E, Badarinath K, Batta S, Masudi T, Dey R, et al. PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest. 2018;128:1807-1819 pubmed publisher
	Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed publisher
	Skopova K, Tomalova B, Kanchev I, Rossmann P, Svedova M, Adkins I, et al. Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis. Infect Immun. 2017;85: pubmed publisher
	Beard R, Yang X, Meegan J, Overstreet J, Yang C, Elliott J, et al. Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome. Nat Commun. 2016;7:12823 pubmed publisher
	Chantzoura E, Skylaki S, Menendez S, Kim S, Johnsson A, Linnarsson S, et al. Reprogramming Roadblocks Are System Dependent. Stem Cell Reports. 2015;5:350-64 pubmed publisher
	Pankratz F, Bemtgen X, Zeiser R, Leonhardt F, Kreuzaler S, Hilgendorf I, et al. MicroRNA-155 Exerts Cell-Specific Antiangiogenic but Proarteriogenic Effects During Adaptive Neovascularization. Circulation. 2015;131:1575-89 pubmed publisher
	Larsen J, Dall M, Antvorskov J, Weile C, Engkilde K, Josefsen K, et al. Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion. Eur J Immunol. 2014;44:3056-67 pubmed publisher
	Reynolds C, Chong D, Raynsford E, Quigley K, Kelly D, Llewellyn Hughes J, et al. Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile. BMC Biol. 2014;12:32 pubmed publisher
	Braach N, Buschmann K, Pflaum J, Hudalla H, Koch L, Ryschich E, et al. Anti-inflammatory functions of protein C require RAGE and ICAM-1 in a stimulus-dependent manner. Mediators Inflamm. 2014;2014:743678 pubmed publisher
	O MALLEY J, Skylaki S, Iwabuchi K, Chantzoura E, Ruetz T, Johnsson A, et al. High-resolution analysis with novel cell-surface markers identifies routes to iPS cells. Nature. 2013;499:88-91 pubmed publisher
	McKee A, Burchill M, Munks M, Jin L, Kappler J, Friedman R, et al. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013;110:E1122-31 pubmed publisher
	Bénézech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, et al. Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010;184:4521-30 pubmed publisher
	Xiao X, Zhao P, Rodriguez Pinto D, Qi D, Henegariu O, Alexopoulou L, et al. Inflammatory regulation by TLR3 in acute hepatitis. J Immunol. 2009;183:3712-9 pubmed publisher
	Webster K, Walters S, Kohler R, Mrkvan T, Boyman O, Surh C, et al. In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J Exp Med. 2009;206:751-60 pubmed publisher
	Noh Y, Lim Y, Chung B. Noninvasive imaging of dendritic cell migration into lymph nodes using near-infrared fluorescent semiconductor nanocrystals. FASEB J. 2008;22:3908-18 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), FITC, eBioscience

Catalog # :

11-0541-81

Quantity :

50 ug

Price :

US 105.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 ug/test

Species :

Mouse

Clone :

YN1/1.7.4

Isotype :

IgG2b, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

more info or order :

Invitrogen product webpage