CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), FITC, eBioscience | Invitrogen 11-0519-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), FITC, eBioscience

catalog :

11-0519-42

quantity :

100 Tests

price :

US 246.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

23C6

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:50; fig 3a, 3b	Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
	Andreucci E, Bugatti K, Peppicelli S, Ruzzolini J, Lulli M, Calorini L, et al. Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer. Int J Mol Sci. 2023;24: pubmed publisher
	Perrins R, McCarthy L, Robinson A, Spry K, Cognet V, Ferreira A, et al. Targeting Ultrasmall Gold Nanoparticles with cRGD Peptide Increases the Uptake and Efficacy of Cytotoxic Payload. Nanomaterials (Basel). 2022;12: pubmed publisher
	Kong S, Kim J, Kim S, Jeong A, Lee S, Ye S, et al. Effect of Denosumab on the Change of Osteoclast Precursors Compared to Zoledronate Treatment in Postmenopausal Women with Osteoporosis. J Bone Metab. 2022;29:93-101 pubmed publisher
	Nagaraj R, Stack T, Yi S, Mathew B, Shull K, Scott E, et al. High Density Display of an Anti-Angiogenic Peptide on Micelle Surfaces Enhances Their Inhibition of αvβ3 Integrin-Mediated Neovascularization In Vitro. Nanomaterials (Basel). 2020;10: pubmed publisher
	Cen B, Wei Y, Huang W, Teng M, He S, Li J, et al. An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo. Mol Ther Nucleic Acids. 2018;13:220-232 pubmed publisher
	Swindle E, Brown J, Radinger M, Deleo F, Metcalfe D. Interferon-γ enhances both the anti-bacterial and the pro-inflammatory response of human mast cells to Staphylococcus aureus. Immunology. 2015;146:470-85 pubmed publisher
	Green C, Fraser S, Day M. Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro. Hum Reprod. 2015;30:284-98 pubmed publisher
	Liu X, Wang W, Samarsky D, Liu L, Xu Q, Zhang W, et al. Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA. Nucleic Acids Res. 2014;42:11805-17 pubmed publisher
	Lescarbeau R, Seib F, Prewitz M, Werner C, Kaplan D. In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors. PLoS ONE. 2012;7:e40372 pubmed publisher
	Sekine C, Koyanagi A, Koyama N, Hozumi K, Chiba S, Yagita H. Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes. Arthritis Res Ther. 2012;14:R45 pubmed publisher
	Mor Cohen R, Rosenberg N, Einav Y, Zelzion E, Landau M, Mansour W, et al. Unique disulfide bonds in epidermal growth factor (EGF) domains of ?3 affect structure and function of ?IIb?3 and ?v?3 integrins in different manner. J Biol Chem. 2012;287:8879-91 pubmed publisher
	Mougiakakos D, Okita R, Ando T, Dürr C, Gadiot J, Ichikawa J, et al. High expression of GCLC is associated with malignant melanoma of low oxidative phenotype and predicts a better prognosis. J Mol Med (Berl). 2012;90:935-44 pubmed publisher
	Kalkunte S, Lai Z, Tewari N, Chichester C, Romero R, Padbury J, et al. In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts. Placenta. 2008;29:871-8 pubmed publisher
	Cao L, Du P, Jiang S, Jin G, Huang Q, Hua Z. Enhancement of antitumor properties of TRAIL by targeted delivery to the tumor neovasculature. Mol Cancer Ther. 2008;7:851-61 pubmed publisher
	Aleman M, de la Barrera S, Schierloh P, Yokobori N, Baldini M, Musella R, et al. Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on the dendritic cell-mediated immune response. Eur J Immunol. 2007;37:1524-37 pubmed

product information

Product Type :

Antibody

Product Name :

CD51/CD61 (Integrin alpha v beta 3) Monoclonal Antibody (23C6), FITC, eBioscience

Catalog # :

11-0519-42

Quantity :

100 Tests

Price :

US 246.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (1 ug)/test

Species :

Human

Clone :

23C6

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex. This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (1 ug)/test

Aliases :

1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen CD61; antigen identified by monoclonal antibody L230; BDPLT16; BDPLT2; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; GT; INGRB3; integrin; integrin alpha V; integrin alpha-5 beta-3; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; Integrin beta; integrin beta 3; integrin beta 3 (Cd61); Integrin beta3; integrin beta-3; integrin subunit alpha V; integrin subunit beta 3; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGAV; Itgb3; MSK8; platelet gpIIIa; platelet membrane glycoprotein IIIa; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor alpha subunit; vitronectin receptor subunit alpha; VNRA; VTNR

more info or order :

Invitrogen product webpage