| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; mouse; loading ...; fig s2f
| Yang J, Tanaka Y, Seay M, Li Z, Jin J, Garmire L, et al. Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors. Nucleic Acids Res. 2017;45:1281-1296 pubmed publisher |
| Koupenova M, Mick E, Corkrey H, Singh A, Tanriverdi S, Vitseva O, et al. Pollen-derived RNAs Are Found in the Human Circulation. iScience. 2019;19:916-926 pubmed publisher |
| Shvartsman M, Bilican S, Lancrin C. Iron deficiency disrupts embryonic haematopoiesis but not the endothelial to haematopoietic transition. Sci Rep. 2019;9:6414 pubmed publisher |
| Koupenova M, Corkrey H, Vitseva O, Manni G, Pang C, Clancy L, et al. The role of platelets in mediating a response to human influenza infection. Nat Commun. 2019;10:1780 pubmed publisher |
| Soukup A, Zheng Y, Mehta C, Wu J, Liu P, Cao M, et al. Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer. J Clin Invest. 2019;129:1180-1192 pubmed publisher |
| Grinenko T, Eugster A, Thielecke L, Ramasz B, Krüger A, Dietz S, et al. Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice. Nat Commun. 2018;9:1898 pubmed publisher |
| Maryanovich M, Zahalka A, Pierce H, Pinho S, Nakahara F, Asada N, et al. Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nat Med. 2018;24:782-791 pubmed publisher |
| Yamamoto R, Wilkinson A, Ooehara J, Lan X, Lai C, Nakauchi Y, et al. Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. Cell Stem Cell. 2018;22:600-607.e4 pubmed publisher |
| Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed publisher |
| Zhang Y, Daubel N, Stritt S, Mäkinen T. Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels. Development. 2018;145: pubmed publisher |
| Zhao B, Mei Y, Cao L, Zhang J, Sumagin R, Yang J, et al. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms. J Clin Invest. 2018;128:125-140 pubmed publisher |
| Nitulescu I, Meyer S, Wen Q, Crispino J, Lemieux M, Levine R, et al. Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation. EBioMedicine. 2017;26:112-125 pubmed publisher |
| Alzubi J, Pallant C, Mussolino C, Howe S, Thrasher A, Cathomen T. Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model. Sci Rep. 2017;7:12475 pubmed publisher |
| Mehta C, Johnson K, Gao X, Ong I, Katsumura K, McIver S, et al. Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program. Cell Rep. 2017;20:2966-2979 pubmed publisher |
| Hewitt K, Katsumura K, Matson D, Devadas P, Tanimura N, Hebert A, et al. GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia. Dev Cell. 2017;42:213-225.e4 pubmed publisher |
| Asada N, Kunisaki Y, Pierce H, Wang Z, Fernandez N, Birbrair A, et al. Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nat Cell Biol. 2017;19:214-223 pubmed publisher |
| Bernitz J, Kim H, MacArthur B, SIEBURG H, Moore K. Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions. Cell. 2016;167:1296-1309.e10 pubmed publisher |
| Jin Q, Ren Y, Wang M, Suraneni P, Li D, Crispino J, et al. Novel function of FAXDC2 in megakaryopoiesis. Blood Cancer J. 2016;6:e478 pubmed publisher |
| Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed publisher |
| Illendula A, Gilmour J, Grembecka J, Tirumala V, Boulton A, Kuntimaddi A, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016;8:117-131 pubmed publisher |
| Pietras E, Mirantes Barbeito C, Fong S, Loeffler D, Kovtonyuk L, Zhang S, et al. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol. 2016;18:607-18 pubmed publisher |
| Liu H, Zhang A, Xu J, Chen Y, Zhu Y. H2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/platelets. J Hematol Oncol. 2016;9:13 pubmed publisher |
| Vargel O, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, et al. Activation of the TGFβ pathway impairs endothelial to haematopoietic transition. Sci Rep. 2016;6:21518 pubmed publisher |
| Johnson K, Kong G, Gao X, Chang Y, Hewitt K, Sanalkumar R, et al. Cis-regulatory mechanisms governing stem and progenitor cell transitions. Sci Adv. 2015;1:e1500503 pubmed publisher |
| Ghanem L, Kromer A, Silverman I, Chatterji P, Traxler E, Penzo Méndez A, et al. The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Mol Cell Biol. 2016;36:304-19 pubmed publisher |
| Clarke R, Robitaille A, Moon R, Keller G. A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17. Stem Cell Reports. 2015;5:291-304 pubmed publisher |
| Beaulieu L, Clancy L, Tanriverdi K, Benjamin E, Kramer C, Weinberg E, et al. Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans. PLoS ONE. 2015;10:e0131688 pubmed publisher |
| Hadland B, Varnum Finney B, Poulos M, Moon R, Butler J, Rafii S, et al. Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells. J Clin Invest. 2015;125:2032-45 pubmed publisher |
| Zhu J, Bi Z, Yang T, Wang W, Li Z, Huang W, et al. Regulation of PKM2 and Nrf2-ARE pathway during benzoquinone induced oxidative stress in yolk sac hematopoietic stem cells. PLoS ONE. 2014;9:e113733 pubmed publisher |
| Wilkinson A, Kawata V, Schütte J, Gao X, Antoniou S, Baumann C, et al. Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification. Development. 2014;141:4018-30 pubmed publisher |
| Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, et al. Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this. Development. 2014;141:3319-23 pubmed publisher |
| Gilmour J, Assi S, Jaegle U, Kulu D, van de Werken H, Clarke D, et al. A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification. Development. 2014;141:2391-401 pubmed publisher |
| Li H, Yue R, Wei B, Gao G, Du J, Pei G. Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. EMBO J. 2014;33:1383-96 pubmed publisher |
| Gong J, Wu Z, Qi H, Chen L, Li H, Li B, et al. Maresin 1 mitigates LPS-induced acute lung injury in mice. Br J Pharmacol. 2014;171:3539-50 pubmed publisher |
| Bénézech C, Nayar S, Finney B, Withers D, Lowe K, Desanti G, et al. CLEC-2 is required for development and maintenance of lymph nodes. Blood. 2014;123:3200-7 pubmed publisher |
| Corken A, Russell S, Dent J, Post S, Ware J. Platelet glycoprotein Ib-IX as a regulator of systemic inflammation. Arterioscler Thromb Vasc Biol. 2014;34:996-1001 pubmed publisher |
| Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun K, et al. Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. J Exp Med. 2014;211:209-15 pubmed publisher |
| Liu L, Wen Q, Gong R, Gilles L, Stankiewicz M, Guo M, et al. PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN. Cell Death Dis. 2014;5:e988 pubmed publisher |
| Yamane T, Washino A, Yamazaki H. Common developmental pathway for primitive erythrocytes and multipotent hematopoietic progenitors in early mouse development. Stem Cell Reports. 2013;1:590-603 pubmed publisher |
| Shen B, Zhao X, O Brien K, Stojanovic Terpo A, Delaney M, Kim K, et al. A directional switch of integrin signalling and a new anti-thrombotic strategy. Nature. 2013;503:131-5 pubmed publisher |
| Yamamoto K, Tsuzuki S, Minami Y, Yamamoto Y, Abe A, Ohshima K, et al. Functionally deregulated AML1/RUNX1 cooperates with BCR-ABL to induce a blastic phase-like phenotype of chronic myelogenous leukemia in mice. PLoS ONE. 2013;8:e74864 pubmed publisher |
| Zhang H, Nieves J, Fraser S, Isern J, Douvaras P, Papatsenko D, et al. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells. 2014;32:191-203 pubmed publisher |
| Yamamoto R, Morita Y, Ooehara J, Hamanaka S, Onodera M, Rudolph K, et al. Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell. 2013;154:1112-1126 pubmed publisher |
| Faraday N, Schunke K, Saleem S, Fu J, Wang B, Zhang J, et al. Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils. PLoS ONE. 2013;8:e71447 pubmed publisher |
| Luo B, Tseng C, Adams G, Lee A. Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells. Stem Cells Dev. 2013;22:3062-73 pubmed publisher |
| Pilat S, Carotta S, Klump H. Development of hematopoietic stem and progenitor cells from mouse embryonic stem cells, in vitro, supported by ectopic human HOXB4 expression. Methods Mol Biol. 2013;1029:129-47 pubmed publisher |
| Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, et al. Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method. Biochem Biophys Res Commun. 2013;435:586-91 pubmed publisher |
| Zeng L, An L, Fang T, Pan B, Sun H, Chen C, et al. A murine model of hepatic veno-occlusive disease induced by allogeneic hematopoietic stem cell transplantation. Cell Biochem Biophys. 2013;67:939-48 pubmed publisher |
| Sato T, Ikeda M, Yotsumoto S, Shimada Y, Higuchi T, Kobayashi H, et al. Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder. Blood. 2013;121:3267-73 pubmed publisher |
| Hasan Z, Rahman M, Palani K, Syk I, Jeppsson B, Thorlacius H. Geranylgeranyl transferase regulates CXC chemokine formation in alveolar macrophages and neutrophil recruitment in septic lung injury. Am J Physiol Lung Cell Mol Physiol. 2013;304:L221-9 pubmed publisher |
| Toyama H, Arai F, Hosokawa K, Ikushima Y, Suda T. N-cadherin+ HSCs in fetal liver exhibit higher long-term bone marrow reconstitution activity than N-cadherin- HSCs. Biochem Biophys Res Commun. 2012;428:354-9 pubmed publisher |
| Lindqvist L, Vikstrom I, Chambers J, McArthur K, Ann Anderson M, Henley K, et al. Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor. Cell Death Dis. 2012;3:e409 pubmed publisher |
| Johnson K, Hsu A, Ryu M, Wang J, Gao X, Boyer M, et al. Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity. J Clin Invest. 2012;122:3692-704 pubmed publisher |
| Barbier V, Winkler I, Levesque J. Mobilization of hematopoietic stem cells by depleting bone marrow macrophages. Methods Mol Biol. 2012;904:117-38 pubmed publisher |
| Tashiro K, Omori M, Kawabata K, Hirata N, Yamaguchi T, Sakurai F, et al. Inhibition of Lnk in mouse induced pluripotent stem cells promotes hematopoietic cell generation. Stem Cells Dev. 2012;21:3381-90 pubmed publisher |
| Gasparetto M, Sekulovic S, Zakaryan A, Imren S, Kent D, Humphries R, et al. Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status. Exp Hematol. 2012;40:857-66.e5 pubmed publisher |
| Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, et al. GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment. Blood. 2012;120:314-22 pubmed publisher |
| Koyano Nakagawa N, Kweon J, Iacovino M, Shi X, Rasmussen T, Borges L, et al. Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression. Stem Cells. 2012;30:1611-23 pubmed publisher |
| Du J, Wang J, Kong G, Jiang J, Zhang J, Liu Y, et al. Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells. Stem Cells. 2012;30:1447-54 pubmed publisher |
| Tanaka Y, Joshi A, Wilson N, Kinston S, Nishikawa S, Göttgens B. The transcriptional programme controlled by Runx1 during early embryonic blood development. Dev Biol. 2012;366:404-19 pubmed publisher |
| Xiao J, Zhang C, Zhang Y, Zhang X, Zhao J, Liang J, et al. Transplantation of adipose-derived mesenchymal stem cells into a murine model of passive chronic immune thrombocytopenia. Transfusion. 2012;52:2551-8 pubmed publisher |
| Barbier V, Winkler I, Wadley R, Levesque J. Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo. Methods Mol Biol. 2012;844:45-63 pubmed publisher |
| Barbier V, Nowlan B, Levesque J, Winkler I. Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells. Methods Mol Biol. 2012;844:31-43 pubmed publisher |
| Yuan H, Wang Z, Li L, Zhang H, Modi H, Horne D, et al. Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis. Blood. 2012;119:1904-14 pubmed publisher |
| Rasmussen T, Kweon J, Diekmann M, Belema Bedada F, Song Q, Bowlin K, et al. ER71 directs mesodermal fate decisions during embryogenesis. Development. 2011;138:4801-12 pubmed publisher |
| Joo H, Kim H, Park S, Cho H, Kim H, Lim D, et al. Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells. Blood. 2011;118:2094-104 pubmed publisher |
| Sprague L, Muccioli M, Pate M, Meles E, McGinty J, Nandigam H, et al. The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells. BMC Immunol. 2011;12:35 pubmed publisher |
| Ding X, Lin Q, Ensenat Waser R, Rose John S, Zenke M. Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells. Stem Cells Dev. 2012;21:121-32 pubmed publisher |
| Weishaupt H, Attema J. A Method to Study the Epigenetic Chromatin States of Rare Hematopoietic Stem and Progenitor Cells; MiniChIP-Chip. Biol Proced Online. 2010;12:1-17 pubmed publisher |
| Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson T, et al. ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes Dev. 2011;25:251-62 pubmed publisher |
| Jung Y, Shiozawa Y, Wang J, Patel L, Havens A, Song J, et al. Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche. Exp Hematol. 2011;39:151-166.e1 pubmed publisher |
| Yokomizo T, Dzierzak E. Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development. 2010;137:3651-61 pubmed publisher |
| Tzeng Y, Li H, Kang Y, Chen W, Cheng W, Lai D. Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression. Blood. 2011;117:429-39 pubmed publisher |
| Ciriza J, Garcia Ojeda M. Expression of migration-related genes is progressively upregulated in murine Lineage-Sca-1+c-Kit+ population from the fetal to adult stages of development. Stem Cell Res Ther. 2010;1:14 pubmed publisher |
| Paz H, Lynch M, Bogue C, Gasson J. The homeobox gene Hhex regulates the earliest stages of definitive hematopoiesis. Blood. 2010;116:1254-62 pubmed publisher |
| Böiers C, Buza Vidas N, Jensen C, Pronk C, Kharazi S, Wittmann L, et al. Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development. Blood. 2010;115:5061-8 pubmed publisher |
| Chou S, Lodish H. Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010;107:7799-804 pubmed publisher |
| Zhang H, Fraser S, Papazoglu C, Hoatlin M, Baron M. Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells. Stem Cells. 2009;27:2884-95 pubmed publisher |
| Sato T, Onai N, Yoshihara H, Arai F, Suda T, Ohteki T. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat Med. 2009;15:696-700 pubmed publisher |
| Lancrin C, Sroczynska P, Stephenson C, Allen T, Kouskoff V, Lacaud G. The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage. Nature. 2009;457:892-5 pubmed publisher |
| Levi B, Yilmaz O, Duester G, Morrison S. Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood. 2009;113:1670-80 pubmed publisher |
| Hahn B, Anderson M, Le E, La Cava A. Anti-DNA Ig peptides promote Treg cell activity in systemic lupus erythematosus patients. Arthritis Rheum. 2008;58:2488-97 pubmed publisher |
| Pronk C, Attema J, Rossi D, Sigvardsson M, Bryder D. Deciphering developmental stages of adult myelopoiesis. Cell Cycle. 2008;7:706-13 pubmed |
| Peng J, Kitchen S, West R, Sigler R, Eisenmann K, Alberts A. Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1. Cancer Res. 2007;67:7565-71 pubmed |
| Vassen L, Okayama T, Moroy T. Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood. 2007;109:2356-64 pubmed |
| Dumon S, Heath V, Tomlinson M, Gottgens B, Frampton J. Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6. Exp Hematol. 2006;34:654-63 pubmed |
| Bertrand J, Giroux S, Golub R, Klaine M, Jalil A, Boucontet L, et al. Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin. Proc Natl Acad Sci U S A. 2005;102:134-9 pubmed |
| Mitjavila Garcia M, Cailleret M, Godin I, Nogueira M, Cohen Solal K, Schiavon V, et al. Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells. Development. 2002;129:2003-13 pubmed |
| Teeling J, Jansen Hendriks T, Kuijpers T, de Haas M, van de Winkel J, Hack C, et al. Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia. Blood. 2001;98:1095-9 pubmed |
| Nieswandt B, Echtenacher B, Wachs F, Schroder J, Gessner J, Schmidt R, et al. Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice. Blood. 1999;94:684-93 pubmed |
