CD7 Monoclonal Antibody (4H9), FITC, eBioscience™ | Invitrogen 11-0078-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD7 Monoclonal Antibody (4H9), FITC, eBioscience™

catalog :

11-0078-41

quantity :

25Tests

price :

US 108

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

4H9

reactivity :

human

application :

flow cytometry

citations: 7

Reference
Ribeiro S, Tesio M, Ribot J, Macintyre E, Barata J, Silva Santos B. Casein kinase 2 controls the survival of normal thymic and leukemic ?? T cells via promotion of AKT signaling. Leukemia. 2017;31:1603-1610 pubmed publisher
Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher
Jo J, Tan A, Ussher J, Sandalova E, Tang X, Tan Garcia A, et al. Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver. PLoS Pathog. 2014;10:e1004210 pubmed publisher
Tang X, Jo J, Tan A, Sandalova E, Chia A, Tan K, et al. IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells. J Immunol. 2013;190:3142-52 pubmed publisher
Seegmiller A, Karandikar N, Kroft S, McKenna R, Xu Y. Overexpression of CD7 in classical Hodgkin lymphoma-infiltrating T lymphocytes. Cytometry B Clin Cytom. 2009;76:169-74 pubmed publisher
Link M, Warnke R, Finlay J, Amylon M, Miller R, Dilley J, et al. A single monoclonal antibody identifies T-cell lineage of childhood lymphoid malignancies. Blood. 1983;62:722-8 pubmed
Weiss L, Crabtree G, Rouse R, Warnke R. Morphologic and immunologic characterization of 50 peripheral T-cell lymphomas. Am J Pathol. 1985;118:316-24 pubmed

product information

Product Type :

Antibody

Product Name :

CD7 Monoclonal Antibody (4H9), FITC, eBioscience™

Catalog # :

11-0078-41

Quantity :

25Tests

Price :

US 108

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test

Species :

Human

Clone :

4H9

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test

Aliases :

GP40, LEU-9, TP41, Tp40