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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD4 Monoclonal Antibody (OX35), FITC, eBioscience™
catalog :
11-0040-82
quantity :
100 µg
price :
US 309.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
OX35
reactivity :
rat
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 25
Reference
Hautz T, Grahammer J, Moser D, Eberhart N, Zelger B, Zelger B, et al. Subcutaneous administration of a neutralizing IL-1β antibody prolongs limb allograft survival. Am J Transplant. 2018;18:2029-2042 pubmed publisher
Liu Y, Sun L, Chen W, Chuai J, Shang Y, Zhang D, et al. Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells. Exp Ther Med. 2018;15:1941-1949 pubmed publisher
Jiao Y, Tan S, Xiong J. Proteomic changes of CD4+/CD25+/forkhead box p3+ regulatory T cells in a 30-day rat model of sepsis survival. Exp Ther Med. 2017;14:5619-5628 pubmed publisher
Zhang Y, Meng Q, Zhang Y, Chen X, Wang Y. Adipose-derived mesenchymal stem cells suppress of acute rejection in small bowel transplantation. Saudi J Gastroenterol. 2017;23:323-329 pubmed publisher
Xie L, Zhong X, Liu D, Liu L, Xia Z. The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model. BMC Complement Altern Med. 2017;17:511 pubmed publisher
Li Y, Li H, Cao Y, Wu F, Ma W, Wang Y, et al. Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance. Mol Med Rep. 2017;16:8137-8145 pubmed publisher
Zheng W, Zhang B, Shen Z, Yin M, Cao Y, Song H. Biological effects of bone marrow mesenchymal stem cells on hepatitis B virus in vitro. Mol Med Rep. 2017;15:2551-2559 pubmed publisher
Sun C, Zhang J, Chen L, Liu T, Xu G, Li C, et al. IL-17 contributed to the neuropathic pain following peripheral nerve injury by promoting astrocyte proliferation and secretion of proinflammatory cytokines. Mol Med Rep. 2017;15:89-96 pubmed publisher
Tang K, Guo D, Zhang L, Guo J, Zheng F, Si J, et al. Immunomodulatory effects of Longdan Xiegan Tang on CD4+/CD8+ T cells and associated inflammatory cytokines in rats with experimental autoimmune uveitis. Mol Med Rep. 2016;14:2746-54 pubmed publisher
Oliveira L, Correia A, Cristina Costa A, Guerra Gomes S, Ferreirinha F, Magalhães Cardoso M, et al. Deficits in endogenous adenosine formation by ecto-5'-nucleotidase/CD73 impair neuromuscular transmission and immune competence in experimental autoimmune myasthenia gravis. Mediators Inflamm. 2015;2015:460610 pubmed publisher
Hautz T, Krapf C, Grahammer J, Zelger B, Hickethier T, Seger C, et al. Targeting the Kv1.3 potassium channel for immunosuppression in vascularized composite allotransplantation - a pilot study. Transpl Int. 2013;26:552-61 pubmed publisher
Liu Y, Wang H, Wang X, Mu L, Kong Q, Wang D, et al. The mechanism of effective electroacupuncture on T cell response in rats with experimental autoimmune encephalomyelitis. PLoS ONE. 2013;8:e51573 pubmed publisher
Lei W, Jian L. Changes of CD4(+) CD25(+) Regulatory T Cells, FoxP3 in Adjuvant Arthritis Rats with Damage of Pulmonary Function and Effects of Tripterygium Glycosides Tablet. Int J Rheumatol. 2012;2012:348450 pubmed publisher
Wang Y, Wang Y, Wang Y, Zheng G, Zhang G, Zhou J, et al. DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats. Kidney Int. 2013;83:223-32 pubmed publisher
Wang G, Zhang Q, Yang Y, Chen W, Liu W, Jiang N, et al. Rapamycin combined with allogenic immature dendritic cells selectively expands CD4+CD25+Foxp3+ regulatory T cells in rats. Hepatobiliary Pancreat Dis Int. 2012;11:203-8 pubmed
Schu S, Nosov M, O Flynn L, Shaw G, Treacy O, Barry F, et al. Immunogenicity of allogeneic mesenchymal stem cells. J Cell Mol Med. 2012;16:2094-103 pubmed publisher
Wang G, Yang Y, Li H, Zhang J, Li M, Zhang Q, et al. Rapamycin combined with donor immature dendritic cells promotes liver allograft survival in association with CD4(+) CD25(+) Foxp3(+) regulatory T cell expansion. Hepatol Res. 2012;42:192-202 pubmed publisher
Wu C, Xia Y, Wang P, Lu L, Zhang F. Triptolide protects mice from ischemia/reperfusion injury by inhibition of IL-17 production. Int Immunopharmacol. 2011;11:1564-72 pubmed publisher
Dominguez M, Lorenzo N, Barbera A, Darrasse Jèze G, Hernández M, Torres A, et al. An altered peptide ligand corresponding to a novel epitope from heat-shock protein 60 induces regulatory T cells and suppresses pathogenic response in an animal model of adjuvant-induced arthritis. Autoimmunity. 2011;44:471-82 pubmed publisher
Maenz M, Morcos M, Ritter T. A comprehensive flow-cytometric analysis of graft infiltrating lymphocytes, draining lymph nodes and serum during the rejection phase in a fully allogeneic rat cornea transplant model. Mol Vis. 2011;17:420-9 pubmed
Fahmi T, Esendagli G, Yilmaz G, Kansu E, Guc D. Immune compartmentalization of T cell subsets in chemically-induced breast cancer. Scand J Immunol. 2010;72:339-48 pubmed publisher
Visser J, Hillebrands J, Walther Boer M, Bos N, Rozing J. Prevention of diabetes by a hydrolysed casein-based diet in diabetes-prone BioBreeding rats does not involve restoration of the defective natural regulatory T cell function. Diabetologia. 2009;52:1445-7 pubmed publisher
Brugman S, Visser J, Hillebrands J, Bos N, Rozing J. Prolonged exclusive breastfeeding reduces autoimmune diabetes incidence and increases regulatory T-cell frequency in bio-breeding diabetes-prone rats. Diabetes Metab Res Rev. 2009;25:380-7 pubmed publisher
Tischner D, Weishaupt A, van den Brandt J, Müller N, Beyersdorf N, Ip C, et al. Polyclonal expansion of regulatory T cells interferes with effector cell migration in a model of multiple sclerosis. Brain. 2006;129:2635-47 pubmed
May E, Dorris M, Satumtira N, Iqbal I, Rehman M, Lightfoot E, et al. CD8 alpha beta T cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats. J Immunol. 2003;170:1099-105 pubmed
product information
Product Type :
Antibody
Product Name :
CD4 Monoclonal Antibody (OX35), FITC, eBioscience™
Catalog # :
11-0040-82
Quantity :
100 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Rat
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Rat
Clone :
OX35
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA