product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD3 Monoclonal Antibody (17A2), FITC, eBioscience
catalog :
11-0032-82
quantity :
100 µg
price :
US 98.75
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
17A2
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 247
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s2b
Fahy N, Palomares Cabeza V, Lolli A, Witte Bouma J, Merino A, Ridwan Y, et al. Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model. Front Immunol. 2021;12:715267 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s6d
Lin Q, Rong L, Jia X, Li R, Yu B, Hu J, et al. IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella. Nat Commun. 2021;12:2537 pubmed publisher
  • flow cytometry; mouse; 1:300; loading ...; fig s7b
Hu X, Deng Q, Ma L, Li Q, Chen Y, Liao Y, et al. Meningeal lymphatic vessels regulate brain tumor drainage and immunity. Cell Res. 2020;30:229-243 pubmed publisher
Peng J, Xiao Y, Yang Q, Liu Q, Chen Y, Shi K, et al. Intracellular aggregation of peptide-reprogrammed small molecule nanoassemblies enhances cancer chemotherapy and combinatorial immunotherapy. Acta Pharm Sin B. 2021;11:1069-1082 pubmed publisher
Wise R, Harrison M, Sullivan B, Al Ghadban S, Aleman S, Vinluan A, et al. Short-Term Rapamycin Preconditioning Diminishes Therapeutic Efficacy of Human Adipose-Derived Stem Cells in a Murine Model of Multiple Sclerosis. Cells. 2020;9: pubmed publisher
Shao B, Wang L, Yu Y, Chen L, Gan N, Huang W. Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation. Exp Ther Med. 2020;20:84 pubmed publisher
Pierini S, Tanyi J, Simpkins F, George E, Uribe Herranz M, Drapkin R, et al. Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target. JCI Insight. 2020;5: pubmed publisher
Buqué A, Bloy N, Pérez Lanzón M, Iribarren K, Humeau J, Pol J, et al. Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer. Nat Commun. 2020;11:3819 pubmed publisher
Liu W, Dai E, Liu Z, Ma C, Guo Z, Bartlett D. In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2. Mol Ther Oncolytics. 2020;17:350-360 pubmed publisher
Luo Z, Liao T, Zhang Y, Zheng H, Sun Q, Han F, et al. Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways. Front Immunol. 2020;11:612 pubmed publisher
Gautam J, Xu L, Nirwane A, Nguyen B, Yao Y. Loss of mural cell-derived laminin aggravates hemorrhagic brain injury. J Neuroinflammation. 2020;17:103 pubmed publisher
Fang D, Tang Q, Kong Y, Wang Q, Gu J, Fang X, et al. MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment. J Immunother Cancer. 2019;7:327 pubmed publisher
Camell C, Günther P, Lee A, Goldberg E, Spadaro O, Youm Y, et al. Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis. Cell Metab. 2019;30:1024-1039.e6 pubmed publisher
Fang Y, Zhu L, An N, Jiang G, Qian J, Zhao R, et al. Blood autophagy defect causes accelerated non-hematopoietic organ aging. Aging (Albany NY). 2019;11:4910-4922 pubmed publisher
Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed publisher
Palmer B, Jatana S, Phelan Dickinson S, Delouise L. Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis. Sci Rep. 2019;9:5085 pubmed publisher
Lee H, Kim K, Ryu J, Jeong H, Lee S, Kim M. Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland. Invest Ophthalmol Vis Sci. 2019;60:430-441 pubmed publisher
Huang J, Yue H, Jiang T, Gao J, Shi Y, Shi B, et al. IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model. Biol Open. 2019;8: pubmed publisher
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Liu Z, Ge Y, Wang H, Ma C, Feist M, Ju S, et al. Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2. Nat Commun. 2018;9:4682 pubmed publisher
Levy Y, Vagima Y, Tidhar A, Aftalion M, Gur D, Nili U, et al. Targeting of the Yersinia pestis F1 capsular antigen by innate-like B1b cells mediates a rapid protective response against bubonic plague. NPJ Vaccines. 2018;3:52 pubmed publisher
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Patel B, Bansal S, Ismahil M, Hamid T, Rokosh G, Mack M, et al. CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload. JACC Basic Transl Sci. 2018;3:230-244 pubmed publisher
Zhang Q, Xu C, Lin S, Zhou H, Yao G, Liu H, et al. Synergistic immunoreaction of acupuncture-like dissolving microneedles containing thymopentin at acupoints in immune-suppressed rats. Acta Pharm Sin B. 2018;8:449-457 pubmed publisher
Peng J, Xiao Y, Li W, Yang Q, Tan L, Jia Y, et al. Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy. Adv Sci (Weinh). 2018;5:1700891 pubmed publisher
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Watanabe K, Luo Y, Da T, Guedan S, Ruella M, Scholler J, et al. Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses. JCI Insight. 2018;3: pubmed publisher
Dangi A, Zhang L, Zhang X, Luo X. Murine CMV induces type 1 IFN that impairs differentiation of MDSCs critical for transplantation tolerance. Blood Adv. 2018;2:669-680 pubmed publisher
Jin H, Yan C, Xiao T, Yan N, Xu J, Zhou L, et al. High fish oil diet promotes liver inflammation and activates the complement system. Mol Med Rep. 2018;17:6852-6858 pubmed publisher
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Saranchova I, Han J, Zaman R, Arora H, Huang H, Fenninger F, et al. Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis. Sci Rep. 2018;8:2924 pubmed publisher
Clark S, Vaughn C, Soroka J, Li X, Tonelli L. Neonatal adoptive transfer of lymphocytes rescues social behaviour during adolescence in immune-deficient mice. Eur J Neurosci. 2018;47:968-978 pubmed publisher
Guo X, Chu L, Ke F, Mu L, Li Z, Cai J, et al. Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells. Oncotarget. 2017;8:108981-108988 pubmed publisher
Quach D, Collins F, Parameswaran N, McCabe L, Britton R. Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice. mSphere. 2018;3: pubmed publisher
Min M, Yan B, Wang P, Landeck L, Chen J, Li W, et al. Rottlerin as a therapeutic approach?in psoriasis: Evidence from in vitro and in vivo studies. PLoS ONE. 2017;12:e0190051 pubmed publisher
Lee P, Gund R, Dutta A, Pincha N, Rana I, Ghosh S, et al. Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of ??T-cells. elife. 2017;6: pubmed publisher
Wang Q, Ning H, Peng H, Wei L, Hou R, Hoft D, et al. Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses. Nat Commun. 2017;8:867 pubmed publisher
Bendtsen K, Hansen C, Krych L, Buschard K, Farlov H, Hansen A. Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice. Comp Med. 2017;67:388-399 pubmed
Marsden M, Loy B, Wu X, Ramirez C, Schrier A, Murray D, et al. In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication. PLoS Pathog. 2017;13:e1006575 pubmed publisher
Magnuson A, Regan D, Fouts J, Booth A, Dow S, Foster M. Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations. Cell Prolif. 2017;50: pubmed publisher
Li M, Wang B, Sun X, Tang Y, Wei X, Ge B, et al. Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells. Front Immunol. 2017;8:824 pubmed publisher
Soto Feliciano Y, Bartlebaugh J, Liu Y, Sanchez Rivera F, Bhutkar A, Weintraub A, et al. PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes. Genes Dev. 2017;31:973-989 pubmed publisher
Yu Q, Wang X, Fan X. A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells. Front Immunol. 2017;8:585 pubmed publisher
Young C, Rorke E, Adhikary G, Xu W, Eckert R. Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype. Cell Death Dis. 2017;8:e2840 pubmed publisher
Zhang M, Liu Y, Li J, Ke M, Yu J, Dou J, et al. A polysaccharide component from Strongylocentrotus nudus eggs inhibited hepatocellular carcinoma in mice by activating T lymphocytes. Oncol Lett. 2017;13:1847-1855 pubmed publisher
Bardina S, Brown J, Michlmayr D, Hoffman K, Sum J, Pletnev A, et al. Chemokine Receptor Ccr7 Restricts Fatal West Nile Virus Encephalitis. J Virol. 2017;91: pubmed publisher
Zhang B, Wang B, Cao S, Wang Y, Wu D. Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-?B signaling and NLRP3 activation. Int J Mol Med. 2017;39:1111-1118 pubmed publisher
Yoshizumi Y, Yukawa H, Iwaki R, Fujinaka S, Kanou A, Kanou Y, et al. Immunomodulatory Effects of Adipose Tissue-Derived Stem Cells on Concanavalin A-Induced Acute Liver Injury in Mice. Cell Med. 2017;9:21-33 pubmed publisher
Gonçalves A, Ferreira L, Manente F, de Faria C, Polesi M, de Andrade C, et al. The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection. Immunology. 2017;151:154-166 pubmed publisher
Gadani S, Smirnov I, Smith A, Overall C, Kipnis J. Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury. J Exp Med. 2017;214:285-296 pubmed publisher
Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed publisher
Yang E, Singh B, Paustian A, Kambayashi T. Diacylglycerol Kinase ? Is a Target To Enhance NK Cell Function. J Immunol. 2016;197:934-41 pubmed publisher
Ochi T, Feng Y, Kitamoto S, Nagao Kitamoto H, Kuffa P, Atarashi K, et al. Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine. Sci Rep. 2016;6:27634 pubmed publisher
Möhle L, Mattei D, Heimesaat M, Bereswill S, Fischer A, Alutis M, et al. Ly6C(hi) Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis. Cell Rep. 2016;15:1945-56 pubmed publisher
Michlmayr D, Bardina S, Rodriguez C, Pletnev A, Lim J. Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance. J Immunol. 2016;196:4622-31 pubmed publisher
Yao Y, Norris E, Mason C, Strickland S. Laminin regulates PDGFR?(+) cell stemness and muscle development. Nat Commun. 2016;7:11415 pubmed publisher
Schleicher U, Paduch K, Debus A, Obermeyer S, König T, Kling J, et al. TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection. Cell Rep. 2016;15:1062-1075 pubmed publisher
Jiang X, Hu C, Arnovitz S, Bugno J, Yu M, Zuo Z, et al. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nat Commun. 2016;7:11452 pubmed publisher
Pourchet A, Fuhrmann S, Pilones K, Demaria S, Frey A, Mulvey M, et al. CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy. EBioMedicine. 2016;5:59-67 pubmed publisher
Yue Y, Li P, Song N, Li B, Li Z, Guo Y, et al. Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model. Mol Med Rep. 2016;13:4183-90 pubmed publisher
Pallangyo C, Ziegler P, Greten F. IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis. J Exp Med. 2015;212:2253-66 pubmed publisher
Millet A, Martin K, Bonnefoy F, Saas P, Mocek J, Alkan M, et al. Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis. J Clin Invest. 2015;125:4107-21 pubmed publisher
Zanvit P, Konkel J, Jiao X, Kasagi S, Zhang D, Wu R, et al. Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis. Nat Commun. 2015;6:8424 pubmed publisher
Kang Y, Bang B, Han K, Hong L, Shim E, Ma J, et al. Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling. Nat Commun. 2015;6:8371 pubmed publisher
Pini M, Touch S, Poirier H, Dalmas E, Niot I, Rouault C, et al. Adipose tissue adaptive response to trans-10,cis-12-conjugated linoleic acid engages alternatively activated M2 macrophages. FASEB J. 2016;30:241-51 pubmed publisher
Krneta T, Gillgrass A, Chew M, Ashkar A. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016;13:628-39 pubmed publisher
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Park S, Chen W, Durmus N, Bleck B, Reibman J, Riemekasten G, et al. The Effects of Antigen-Specific IgG1 Antibody for the Pulmonary-Hypertension-Phenotype and B Cells for Inflammation in Mice Exposed to Antigen and Fine Particles from Air Pollution. PLoS ONE. 2015;10:e0129910 pubmed publisher
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Teng X, Tian M, Li J, Tan S, Yuan X, Yu Q, et al. Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine. Hum Vaccin Immunother. 2015;11:1456-64 pubmed publisher
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Zhao P, Shi X, Li C, Ayana D, Niu J, Feng J, et al. IL-33 Enhances Humoral Immunity Against Chronic HBV Infection Through Activating CD4(+)CXCR5(+) TFH Cells. J Interferon Cytokine Res. 2015;35:454-63 pubmed publisher
Dong B, Li D, Li R, Chen S, Liu W, Liu W, et al. A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans. PLoS ONE. 2014;9:e114113 pubmed publisher
Habbeddine M, Verbeke P, Karaz S, Bobé P, Kanellopoulos Langevin C. Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface. PLoS ONE. 2014;9:e107267 pubmed publisher
Menon M, Sawada A, Chaturvedi A, Mishra P, Schuster Gossler K, Galla M, et al. Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet. 2014;10:e1004558 pubmed publisher
Han Y, Ling M, Mao H, Zheng J, Liu M, Lam K, et al. Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice. PLoS ONE. 2014;9:e86166 pubmed publisher
Marandu T, Finsterbusch K, Kröger A, Cicin Sain L. Mouse CMV infection delays antibody class switch upon an unrelated virus challenge. Exp Gerontol. 2014;54:101-8 pubmed publisher
Spees A, Kingsbury D, Wangdi T, Xavier M, Tsolis R, BAUMLER A. Neutrophils are a source of gamma interferon during acute Salmonella enterica serovar Typhimurium colitis. Infect Immun. 2014;82:1692-7 pubmed publisher
Orr M, Beebe E, Hudson T, Moon J, Fox C, Reed S, et al. A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93. PLoS ONE. 2014;9:e83884 pubmed publisher
Bodhankar S, Chen Y, Vandenbark A, Murphy S, Offner H. Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice. Metab Brain Dis. 2014;29:59-73 pubmed publisher
Silaeva Y, Grinenko T, Vagida M, Kalinina A, Khromykh L, Kazansky D. Immune selection of tumor cells in TCR ?-chain transgenic mice. J Immunotoxicol. 2014;11:393-9 pubmed publisher
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Murphy K, Erickson J, Johnson C, Seiler C, Bedi J, Hu P, et al. CD8+ T cell-independent tumor regression induced by Fc-OX40L and therapeutic vaccination in a mouse model of glioma. J Immunol. 2014;192:224-33 pubmed publisher
Yeremenko N, Härle P, Cantaert T, van Tok M, van Duivenvoorde L, Bosserhoff A, et al. The cartilage protein melanoma inhibitory activity contributes to inflammatory arthritis. Rheumatology (Oxford). 2014;53:438-47 pubmed publisher
Vom Berg J, Vrohlings M, Haller S, Haimovici A, Kulig P, Sledzińska A, et al. Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection. J Exp Med. 2013;210:2803-11 pubmed publisher
Rao M, Vogelzang A, Kaiser P, Schuerer S, Kaufmann S, Gengenbacher M. The tuberculosis vaccine candidate Bacillus Calmette-Guérin ?ureC::hly coexpressing human interleukin-7 or -18 enhances antigen-specific T cell responses in mice. PLoS ONE. 2013;8:e78966 pubmed publisher
Mahaweni N, Kaijen Lambers M, Dekkers J, Aerts J, Hegmans J. Tumour-derived exosomes as antigen delivery carriers in dendritic cell-based immunotherapy for malignant mesothelioma. J Extracell Vesicles. 2013;2: pubmed publisher
Khattar R, Luft O, Yavorska N, Shalev I, Phillips M, Adeyi O, et al. Targeted deletion of FGL2 leads to increased early viral replication and enhanced adaptive immunity in a murine model of acute viral hepatitis caused by LCMV WE. PLoS ONE. 2013;8:e72309 pubmed publisher
Chen Y, Chen T, Pai L, Wesoly J, Bluyssen H, Lee C. A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors. J Exp Med. 2013;210:2515-22 pubmed publisher
Pozharskaya T, Lane A. Interferon gamma causes olfactory dysfunction without concomitant neuroepithelial damage. Int Forum Allergy Rhinol. 2013;3:861-5 pubmed publisher
Hu M, Wang C, Zhang G, Saito M, Wang Y, Fernandez M, et al. Infiltrating Foxp3(+) regulatory T cells from spontaneously tolerant kidney allografts demonstrate donor-specific tolerance. Am J Transplant. 2013;13:2819-30 pubmed publisher
Åhsberg J, Ungerbäck J, Strid T, Welinder E, Stjernberg J, Larsson M, et al. Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner. J Biol Chem. 2013;288:33449-61 pubmed publisher
Baccarella A, Fontana M, Chen E, Kim C. Toll-like receptor 7 mediates early innate immune responses to malaria. Infect Immun. 2013;81:4431-42 pubmed publisher
Yeung M, McGrath M, Nakayama M, Shimizu T, Boenisch O, Magee C, et al. Interruption of dendritic cell-mediated TIM-4 signaling induces regulatory T cells and promotes skin allograft survival. J Immunol. 2013;191:4447-55 pubmed publisher
Yamanaka D, Motoi M, Ishibashi K, Miura N, Adachi Y, Ohno N. Modulation of interferon-? synthesis by the effects of lignin-like enzymatically polymerized polyphenols on antigen-presenting cell activation and the subsequent cell-to-cell interactions. Food Chem. 2013;141:4073-80 pubmed publisher
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Patnode M, Cheng C, Chou C, Singer M, Elin M, Uchimura K, et al. Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue. J Biol Chem. 2013;288:26533-45 pubmed publisher
Silaeva Y, Kalinina A, Vagida M, Khromykh L, Deikin A, Ermolkevich T, et al. Decrease in pool of T lymphocytes with surface phenotypes of effector and central memory cells under influence of TCR transgenic ?-chain expression. Biochemistry (Mosc). 2013;78:549-59 pubmed publisher
Steelman A, Smith R, Welsh C, Li J. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis. J Biol Chem. 2013;288:23776-87 pubmed publisher
Haasken S, Auger J, Taylor J, Hobday P, Goudy B, Titcombe P, et al. Macrophage scavenger receptor 1 (Msr1, SR-A) influences B cell autoimmunity by regulating soluble autoantigen concentration. J Immunol. 2013;191:1055-62 pubmed publisher
Yeh L, Miaw S, Lin M, Chou F, Shieh S, Chuang Y, et al. Different modulation of Ptpn22 in effector and regulatory T cells leads to attenuation of autoimmune diabetes in transgenic nonobese diabetic mice. J Immunol. 2013;191:594-607 pubmed publisher
Gautron L, Rutkowski J, Burton M, Wei W, Wan Y, Elmquist J. Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen. J Comp Neurol. 2013;521:3741-67 pubmed publisher
Shakya A, Holmdahl R, Nandakumar K, Kumar A. Characterization of chemically defined poly-N-isopropylacrylamide based copolymeric adjuvants. Vaccine. 2013;31:3519-27 pubmed publisher
Wang Y, Wang S, Wei Y, Du D, Xu H, Gao C, et al. Notch-RBP-J signaling is required by bone marrow stromal cells for the treatment of acute graft versus host disease. Stem Cell Res. 2013;11:721-35 pubmed publisher
Zamanian Daryoush M, Lindner D, Tallant T, Wang Z, Buffa J, Klipfell E, et al. The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects. J Biol Chem. 2013;288:21237-52 pubmed publisher
Fujimura K, Oyamada A, Iwamoto Y, Yoshikai Y, Yamada H. CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development. J Leukoc Biol. 2013;94:271-9 pubmed publisher
Tao X, Ma J, Zhang Y, Yu J, Cai L, Wang J, et al. Neutralization of IL-4 and IFN-? Facilitates inducing TGF-?-induced CD4(+)Foxp3(+) Regulatory Cells. Int J Biomed Sci. 2008;4:52-7 pubmed
Stehle F, Schulz K, Fahldieck C, Kalich J, Lichtenfels R, Riemann D, et al. Reduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors. J Biol Chem. 2013;288:16334-47 pubmed publisher
Loubaki L, Tremblay T, Bazin R. In vivo depletion of leukocytes and platelets following injection of T cell-specific antibodies into mice. J Immunol Methods. 2013;393:38-44 pubmed publisher
Eissler N, Mysliwietz J, Deppisch N, Ruf P, Lindhofer H, Mocikat R. Potential of the trifunctional bispecific antibody surek depends on dendritic cells: rationale for a new approach of tumor immunotherapy. Mol Med. 2013;19:54-61 pubmed publisher
You D, Marr N, Saravia J, Shrestha B, Lee G, Turvey S, et al. IL-4R? on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates. J Leukoc Biol. 2013;93:933-42 pubmed publisher
Zhang Y, Jones M, McCabe A, Winslow G, Avram D, MacNamara K. MyD88 signaling in CD4 T cells promotes IFN-? production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection. J Immunol. 2013;190:4725-35 pubmed publisher
Dekhtiarenko I, Jarvis M, Ruzsics Z, Cicin Sain L. The context of gene expression defines the immunodominance hierarchy of cytomegalovirus antigens. J Immunol. 2013;190:3399-409 pubmed publisher
Koyama M, Kuns R, Olver S, Lineburg K, Lor M, Teal B, et al. Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood. 2013;121:3511-20 pubmed publisher
Laperchia C, Allegra Mascaro A, Sacconi L, Andrioli A, Matte A, De Franceschi L, et al. Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo. PLoS ONE. 2013;8:e56144 pubmed publisher
Park S, Chen W, Hoffman C, Marsh L, West J, Grunig G. Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene. PLoS ONE. 2013;8:e55180 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
CD3 Monoclonal Antibody (17A2), FITC, eBioscience
Catalog # :
11-0032-82
Quantity :
100 µg
Price :
US 98.75
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Frozen): 10 µg/mL
Species :
Mouse
Clone :
17A2
Isotype :
IgG2b, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
The CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. The genes encoding the CD3 epsilon, gamma and delta polypeptides are located on chromosome 11. Defects in the CD3 gene are associated with CD3 immunodeficiency.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Frozen): 10 µg/mL
Aliases :
4930549J05Rik; A430104F18Rik; AI504783; antigen CD3D, delta polypeptide (TiT3 complex); antigen CD3E, epsilon polypeptide (TiT3 complex); antigen CD3G, gamma polypeptide; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; CD3; CD3 antigen delta chain; CD3 antigen delta polypeptide; CD3 antigen gamma chain; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 antigen, zeta polypeptide; CD3 delta; CD3 epsilon; CD3 epsilon chain; CD3 epsilon subunit; CD3 epsilon subunit precursor; CD3 gamma-chain; CD3 glycoprotein; CD3 glycoprotein precursor; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; CD3 protein; CD3 TCR complex; CD3 type I transmembrane glycoprotein; CD3 type I transmembrane glycoprotein precursor; CD3 zeta chain; Cd3d; CD3D antigen delta; CD3D antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3E antigen, epsilon polypeptide; CD3E antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; Cd3-eta; Cd3g; CD3G antigen, gamma polypeptide; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Cd3h; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; Ctg3; Ctg-3; FLJ18683; IMD17; IMD18; IMD19; IMD25; Leu-4; OKT3, delta chain; T cell antigen receptor complex epsilon subunit of T3; T3/TCR complex; T3d; T3e; T3g; T3Z; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 epsilon chain; T-cell receptor CD3 epsilon subunit; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 delta chain; T-cell receptor T3 eta chain; T-cell receptor T3 gamma chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; T-cell surface glycoprotein CD3 zeta chain; T-cell surface protein; TcR CD3 delta-chain; TcR CD3 gamma-chain; TCR zeta chain; TCR zeta chain subunit; TCRE; Tcrk; TCRZ; TCRzeta; TiT3 complex; type I transmembrane protein; T-cell surface molecule CD3
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA