product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD63 Monoclonal Antibody (Ts63)
catalog :
10628D
quantity :
200 uL
price :
US 336.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Ts63
reactivity :
human, mouse
application :
western blot, ELISA
more info or order :
citations: 137
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3b
Lim K, Dayem A, Choi Y, Lee Y, An J, Gil M, et al. High Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues. Antioxidants (Basel). 2021;10: pubmed publisher
  • ELISA; human; fig 3b
  • western blot; human; fig 4b
Sun L, Meckes D. Multiplex protein profiling method for extracellular vesicle protein detection. Sci Rep. 2021;11:12477 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s1d
Jang S, Economides K, Moniz R, Sia C, Lewis N, McCoy C, et al. ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance. Commun Biol. 2021;4:497 pubmed publisher
  • western blot; human; fig 2c
Patel G, Khan M, Bhardwaj A, Srivastava S, Zubair H, Patton M, et al. Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK. Br J Cancer. 2017;116:609-619 pubmed publisher
  • western blot; human; loading ...; fig 1b
Kreger B, Johansen E, Cerione R, Antonyak M. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers (Basel). 2016;8: pubmed
  • western blot; human; fig 4b
Bobis Wozowicz S, Kmiotek K, Kania K, Karnas E, Labedz Maslowska A, Sekula M, et al. Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles. J Mol Med (Berl). 2017;95:205-220 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4c
Kreger B, Dougherty A, Greene K, Cerione R, Antonyak M. Microvesicle Cargo and Function Changes upon Induction of Cellular Transformation. J Biol Chem. 2016;291:19774-85 pubmed publisher
Mamand D, Bazaz S, Mohammad D, Liang X, Pavlova S, Mim C, et al. Extracellular vesicles originating from melanoma cells promote dysregulation in haematopoiesis as a component of cancer immunoediting. J Extracell Vesicles. 2024;13:e12471 pubmed publisher
Mishra A, Zehra S, Bharti P, Mathur S, Ranjan P, Batra A, et al. Spectroscopic insight into breast cancer: profiling small extracellular vesicles lipids via infrared spectroscopy for diagnostic precision. Sci Rep. 2024;14:9347 pubmed publisher
Gorai P, Rastogi S, Bharti P, Agarwal S, Pal S, Sharma M, et al. Deciphering pancreatic neuroendocrine tumors: Unveiling through circulating small extracellular vesicles. Heliyon. 2024;10:e29079 pubmed publisher
Giulietti M, Piva F, Cecati M, Maggio S, Guescini M, Saladino T, et al. Effects of Eribulin on the RNA Content of Extracellular Vesicles Released by Metastatic Breast Cancer Cells. Cells. 2024;13: pubmed publisher
Carreras Mascaro A, Grochowska M, Boumeester V, Dits N, Bilgi x4ab E, Breedveld G, et al. LRP10 and α-synuclein transmission in Lewy body diseases. Cell Mol Life Sci. 2024;81:75 pubmed publisher
Dong L, Feng M, Kuczler M, Horie K, Kim C, Ma Z, et al. Tumour tissue-derived small extracellular vesicles reflect molecular subtypes of bladder cancer. J Extracell Vesicles. 2024;13:e12402 pubmed publisher
Lau H, Passalacqua I, Jung J, Kwon Y, Zocco D, Park S, et al. Unraveling the surface marker signature of cell-derived vesicles via proteome analysis and nanoparticle flow cytometry. Sci Rep. 2024;14:121 pubmed publisher
Alonso Crisostomo L, Trendell J, Ferraresso M, Bailey S, Ward D, Scurlock Z, et al. Testicular germ cell tumour cells release microRNA-containing extracellular vesicles that induce phenotypic and genotypic changes in cells of the tumour microenvironment. Int J Cancer. 2024;154:372-388 pubmed publisher
Rovere M, Reverberi D, Arnaldi P, Palam xe0 M, Gentili C. Spheroid size influences cellular senescence and angiogenic potential of mesenchymal stromal cell-derived soluble factors and extracellular vesicles. Front Bioeng Biotechnol. 2023;11:1297644 pubmed publisher
Huang C, Zhao Y, Lin S, Li L, Guo X, Yumiseba S, et al. Characterization of human placenta-derived exosome (pExo) as a potential osteoarthritis disease modifying therapeutic. Arthritis Res Ther. 2023;25:229 pubmed publisher
Cross T, xd8 vsteb xf8 R, Brusletto B, Tr xf8 seid A, Olstad O, Aspelin T, et al. RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms. Int J Mol Sci. 2023;24: pubmed publisher
Takeda N, Tsuchiya A, Mito M, Natsui K, Natusi Y, Koseki Y, et al. Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis. Inflamm Regen. 2023;43:48 pubmed publisher
Lapin M, Tjensvoll K, Nedreb xf8 K, Taksdal E, Janssen H, Gilje B, et al. Extracellular vesicles as a potential source of tumor-derived DNA in advanced pancreatic cancer. PLoS ONE. 2023;18:e0291623 pubmed publisher
Cross T, Haug K, Brusletto B, Ommundsen S, Tr xf8 seid A, Aspelin T, et al. Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?. Int J Mol Sci. 2023;24: pubmed publisher
Rastogi S, Rani K, Rai S, Singh R, Bharti P, Sharma V, et al. Fluorescence-tagged salivary small extracellular vesicles as a nanotool in early diagnosis of Parkinson's disease. BMC Med. 2023;21:335 pubmed publisher
Cruz Burgos M, Cort xe9 s Ram xed rez S, Losada Garc xed a A, Morales Pacheco M, Mart xed nez Mart xed nez E, Morales Montor J, et al. Unraveling the Role of EV-Derived miR-150-5p in Prostate Cancer Metastasis and Its Association with High-Grade Gleason Scores: Implications for Diagnosis. Cancers (Basel). 2023;15: pubmed publisher
Liang W, Sagar S, Ravindran R, Najor R, Quiles J, Chi L, et al. Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired. Nat Commun. 2023;14:5031 pubmed publisher
Affolter A, Liebel K, Tengler L, Seiz E, Tiedtke M, Azhakesan A, et al. Modulation of PD‑L1 expression by standard therapy in head and neck cancer cell lines and exosomes. Int J Oncol. 2023;63: pubmed publisher
Beatriz M, Rodrigues R, Vila xe7 a R, Egas C, Pinheiro P, Daley G, et al. Extracellular vesicles improve GABAergic transmission in Huntington's disease iPSC-derived neurons. Theranostics. 2023;13:3707-3724 pubmed publisher
Tengler L, Sch xfc tz J, Tiedtke M, Jablonska J, Theodoraki M, Nitschke K, et al. Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patients. Mol Med. 2023;29:69 pubmed publisher
Li S, Kong Z, Ma B, Wang H, Han Y, Zhao H, et al. Low miR-182-5p Expressing Extracellular Vesicles Derived From Human Bone Marrow Stromal Cells of Subjects With Steroid-Induced Osteonecrosis of the Femoral Head Aggravate Disease Progression. J Bone Miner Res. 2023;38:976-993 pubmed publisher
Bernuz M, Pallar xe8 s Rusi xf1 ol A, Rossi R, Fern xe1 ndez Senac C, Mart xed M, Pividori M. Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications. Methods Mol Biol. 2023;2668:257-276 pubmed publisher
Celikkaya B, Durak T, Farooqi A, Inci K, Tokgun P, Tokgun O. The effects of MYC on exosomes derived from cancer cells in the context of breast cancer. Chem Biol Drug Des. 2023;102:65-75 pubmed publisher
Muraki R, Morita Y, Ida S, Kitajima R, Furuhashi S, Takeda M, et al. Phosphatidylcholine in bile-derived small extracellular vesicles as a novel biomarker of cholangiocarcinoma. Cancer Med. 2023;12:13007-13018 pubmed publisher
Aas V, xd8 vsteb xf8 R, Brusletto B, Aspelin T, Tr xf8 seid A, Qureshi S, et al. Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation. Front Physiol. 2023;14:1143966 pubmed publisher
Palam xe0 M, Coco S, Shaw G, Reverberi D, Ghelardoni M, Ostano P, et al. Xeno-free cultured mesenchymal stromal cells release extracellular vesicles with a "therapeutic" miRNA cargo ameliorating cartilage inflammation in vitro. Theranostics. 2023;13:1470-1489 pubmed publisher
Kim J, Park C, Sung J, Seo D, Choi S, Hong Y. Small RNA sequencing of circulating small extracellular vesicles microRNAs in patients with amyotrophic lateral sclerosis. Sci Rep. 2023;13:5528 pubmed publisher
Perez G, Bernard M, Vocelle D, Zarea A, Saleh N, Gagea M, et al. Phosphatidylserine-Exposing Annexin A1-Positive Extracellular Vesicles: Potential Cancer Biomarkers. Vaccines (Basel). 2023;11: pubmed publisher
Weber B, Henrich D, Schindler C, Marzi I, Leppik L. Release of exosomes in polytraumatized patients: The injury pattern is reflected by the surface epitopes. Front Immunol. 2023;14:1107150 pubmed publisher
Gasparini G, Tasso R, Palam xe0 M, Ciferri M, Gentili C, Di Zenzo G, et al. Pilot study investigating BP-180 in extracellular vesicles derived from blister fluid of bullous pemphigoid patients. Arch Dermatol Res. 2023;315:1837-1841 pubmed publisher
Palsa K, Baringer S, Shenoy G, Spiegelman V, Simpson I, Connor J. Exosomes are involved in iron transport from human blood-brain barrier endothelial cells and are modified by endothelial cell iron status. J Biol Chem. 2023;299:102868 pubmed publisher
Liang Z, Lin S, Pan N, Zhong G, Qiu Z, Kuang S, et al. UCMSCs-derived exosomal circHIPK3 promotes ulcer wound angiogenesis of diabetes mellitus via miR-20b-5p/Nrf2/VEGFA axis. Diabet Med. 2023;40:e14968 pubmed publisher
Hu L, Wang B, Fan Y, He Z, Zheng W. Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage. Neural Regen Res. 2023;18:560-567 pubmed publisher
Akhavan Rahnama M, Soufi Zomorrod M, Abroun S, Atashi A. The Effect of Exosomes Derived from Unrestricted Somatic Stem Cells on Murine Model of Sepsis. Cells Tissues Organs. 2023;212:164-175 pubmed publisher
Perez G, Broadbent D, Zarea A, Dolgikh B, Bernard M, Withrow A, et al. In Vitro and In Vivo Analysis of Extracellular Vesicle-Mediated Metastasis Using a Bright, Red-Shifted Bioluminescent Reporter Protein. Adv Genet (Hoboken). 2022;3:2100055 pubmed publisher
Lim K, Han J, Lee Y, Park J, Dayem A, Myung S, et al. Rapid production method with increased yield of high-purity extracellular vesicles obtained using extended mitochondrial targeting domain peptide. J Extracell Vesicles. 2022;11:e12274 pubmed publisher
Santos M, Rappa G, Fontana S, Karbanov xe1 J, Aalam F, Tai D, et al. Anti-Human CD9 Fab Fragment Antibody Blocks the Extracellular Vesicle-Mediated Increase in Malignancy of Colon Cancer Cells. Cells. 2022;11: pubmed publisher
. Late Breaking Orals. J Extracell Vesicles. 2022;11:e12252 pubmed publisher
Fan X, Cyganek L, Nitschke K, Uhlig S, Nuhn P, Bieback K, et al. Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Int J Mol Sci. 2022;23: pubmed publisher
Dro x17c d x17c A, Ko x142 odziej T, Wr xf3 bel S, Misztal K, Targosz Korecka M, Drab M, et al. Large extracellular vesicles do not mitigate the harmful effect of hyperglycemia on endothelial cell mobility. Eur J Cell Biol. 2022;101:151266 pubmed publisher
Sayeed N, Sugaya K. Exosome mediated Tom40 delivery protects against hydrogen peroxide-induced oxidative stress by regulating mitochondrial function. PLoS ONE. 2022;17:e0272511 pubmed publisher
Wright A, Snyder O, Christenson L, He H, Weiss M. Effect of Pre-Processing Storage Condition of Cell Culture-Conditioned Medium on Extracellular Vesicles Derived from Human Umbilical Cord-Derived Mesenchymal Stromal Cells. Int J Mol Sci. 2022;23: pubmed publisher
Lee J, Jung K, Mina K, Lee K. Extracellular vesicles deliver sodium iodide symporter protein and promote cancer cell radioiodine therapy. Sci Rep. 2022;12:11190 pubmed publisher
Zhang X, Takeuchi T, Takeda A, Mochizuki H, Nagai Y. Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle fractions alter content profiles from plasma extracellular vesicle fractions. PLoS ONE. 2022;17:e0270634 pubmed publisher
Cohn W, Zhu C, Campagna J, Bilousova T, Spilman P, Teter B, et al. Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue. Int J Mol Sci. 2022;23: pubmed publisher
van den Broek B, Wuyts C, Sisto A, Pintelon I, Timmermans J, Somers V, et al. Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles. Cell Commun Signal. 2022;20:58 pubmed publisher
Li C, An Y, Sun Y, Yang F, Xu Q, Wang Z. Adipose Mesenchymal Stem Cell-Derived Exosomes Promote Wound Healing Through the WNT/β-catenin Signaling Pathway in Dermal Fibroblasts. Stem Cell Rev Rep. 2022;18:2059-2073 pubmed publisher
Barnes B, Caws T, Thomas S, Shephard A, Corteling R, Hole P, et al. Investigating heparin affinity chromatography for extracellular vesicle purification and fractionation. J Chromatogr A. 2022;1670:462987 pubmed publisher
Jablonska J, Rist M, Spyra I, Tengler L, Domnich M, Kansy B, et al. Evaluation of Immunoregulatory Biomarkers on Plasma Small Extracellular Vesicles for Disease Progression and Early Therapeutic Response in Head and Neck Cancer. Cells. 2022;11: pubmed publisher
Anakor E, Milla V, Connolly O, Martinat C, Pradat P, Dumonceaux J, et al. The Neurotoxicity of Vesicles Secreted by ALS Patient Myotubes Is Specific to Exosome-Like and Not Larger Subtypes. Cells. 2022;11: pubmed publisher
Ortega González P, Taylor G, Jangra R, Tenorio R, Fernandez de Castro I, Mainou B, et al. Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis. PLoS Pathog. 2022;18:e1010322 pubmed publisher
Strybel U, Marczak L, Zeman M, Polanski K, Miela x144 czyk x, Klymenko O, et al. Molecular Composition of Serum Exosomes Could Discriminate Rectal Cancer Patients with Different Responses to Neoadjuvant Radiotherapy. Cancers (Basel). 2022;14: pubmed publisher
Morales Prieto D, Murrieta Coxca J, Stojiljkovic M, Diezel C, Streicher P, Henao Restrepo J, et al. Small Extracellular Vesicles from Peripheral Blood of Aged Mice Pass the Blood-Brain Barrier and Induce Glial Cell Activation. Cells. 2022;11: pubmed publisher
Komuro H, Aminova S, Lauro K, Woldring D, Harada M. Design and Evaluation of Engineered Extracellular Vesicle (EV)-Based Targeting for EGFR-Overexpressing Tumor Cells Using Monobody Display. Bioengineering (Basel). 2022;9: pubmed publisher
Le Gall L, Duddy W, Martinat C, Mariot V, Connolly O, Milla V, et al. Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles. J Cachexia Sarcopenia Muscle. 2022;13:1385-1402 pubmed publisher
Giraud R, Moyon A, Simoncini S, Duchez A, Nail V, Chareyre C, et al. Tracking Radiolabeled Endothelial Microvesicles Predicts Their Therapeutic Efficacy: A Proof-of-Concept Study in Peripheral Ischemia Mouse Model Using SPECT/CT Imaging. Pharmaceutics. 2022;14: pubmed publisher
Moura S, Pallar xe8 s Rusi xf1 ol A, Sappia L, Mart xed M, Pividori M. The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design. Biosens Bioelectron. 2022;198:113826 pubmed publisher
Pesce E, Manfrini N, Cordiglieri C, Santi S, Bandera A, Gobbini A, et al. Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response. Front Immunol. 2021;12:785941 pubmed publisher
Fontaine M, Herkenne S, Ek O, Paquot A, Boeckx A, Paques C, et al. Extracellular Vesicles Mediate Communication between Endothelial and Vascular Smooth Muscle Cells. Int J Mol Sci. 2021;23: pubmed publisher
Vestad B, Nyman T, Hove Skovsgaard M, Stensland M, Hoel H, Tr xf8 seid A, et al. Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk. Sci Rep. 2021;11:21936 pubmed publisher
Penders J, Nagelkerke A, Cunnane E, Pedersen S, Pence I, Coombes R, et al. Single Particle Automated Raman Trapping Analysis of Breast Cancer Cell-Derived Extracellular Vesicles as Cancer Biomarkers. ACS Nano. 2021;15:18192-18205 pubmed publisher
Elmore Z, Patrick Havlik L, Oh D, Anderson L, Daaboul G, Devlin G, et al. The membrane associated accessory protein is an adeno-associated viral egress factor. Nat Commun. 2021;12:6239 pubmed publisher
Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S. Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin. Redox Biol. 2021;47:102174 pubmed publisher
Qi Z, Xue Q, Wang H, Cao B, Su Y, Xing Q, et al. Serum CD203c+ Extracellular Vesicle Serves as a Novel Diagnostic and Prognostic Biomarker for Succinylated Gelatin Induced Perioperative Hypersensitive Reaction. Front Immunol. 2021;12:732209 pubmed publisher
Biadglegne F, Rademacher P, De Sulbaran Y, K xf6 nig B, Rodloff A, Zedler U, et al. Exosomes in serum‑free cultures of THP‑1 macrophages infected with Mycobacterium tuberculosis. Mol Med Rep. 2021;24: pubmed publisher
G x142 uszko A, Szczepa x144 ski M, Whiteside T, Reichert T, Siewiera J, Ludwig N. Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia. Cancers (Basel). 2021;13: pubmed publisher
Ayala Ramírez P, Machuca Acevedo C, Gámez T, Quijano S, Barreto A, Silva J, et al. Assessment of Placental Extracellular Vesicles-Associated Fas Ligand and TNF-Related Apoptosis-Inducing Ligand in Pregnancies Complicated by Early and Late Onset Preeclampsia. Front Physiol. 2021;12:708824 pubmed publisher
Stelling M, Soares M, Cardoso S, Motta J, de Abreu J, Antunes M, et al. Manganese systemic distribution is modulated in vivo during tumor progression and affects tumor cell migration and invasion in vitro. Sci Rep. 2021;11:15833 pubmed publisher
Zieren R, Dong L, Clark D, Kuczler M, Horie K, Moreno L, et al. Defining candidate mRNA and protein EV biomarkers to discriminate ccRCC and pRCC from non-malignant renal cells in vitro. Med Oncol. 2021;38:105 pubmed publisher
Qi Z, Zhao Y, Su Y, Cao B, Yang J, Xing Q. Serum Extracellular Vesicle-Derived miR-124-3p as a Diagnostic and Predictive Marker for Early-Stage Acute Ischemic Stroke. Front Mol Biosci. 2021;8:685088 pubmed publisher
Wang M, Lv C, Li S, Wang J, Luo W, Zhao P, et al. Near infrared light fluorescence imaging-guided biomimetic nanoparticles of extracellular vesicles deliver indocyanine green and paclitaxel for hyperthermia combined with chemotherapy against glioma. J Nanobiotechnology. 2021;19:210 pubmed publisher
Kakiuchi Y, Kuroda S, Kanaya N, Kumon K, Tsumura T, Hashimoto M, et al. Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles. Mol Ther. 2021;29:2920-2930 pubmed publisher
Li S, Stöckl S, Lukas C, Herrmann M, Brochhausen C, König M, et al. Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p. Stem Cell Res Ther. 2021;12:252 pubmed publisher
Komuro H, Kawai Harada Y, Aminova S, Pascual N, Malik A, Contag C, et al. Engineering Extracellular Vesicles to Target Pancreatic Tissue In Vivo. Nanotheranostics. 2021;5:378-390 pubmed publisher
Yang Z, Wang W, Zhao L, Wang X, Gimple R, Xu L, et al. Plasma cells shape the mesenchymal identity of ovarian cancers through transfer of exosome-derived microRNAs. Sci Adv. 2021;7: pubmed publisher
Glady A, Vandebroek A, Yasui M. Human keratinocyte-derived extracellular vesicles activate the MAPKinase pathway and promote cell migration and proliferation in vitro. Inflamm Regen. 2021;41:4 pubmed publisher
Gorji Bahri G, Moradtabrizi N, Vakhshiteh F, Hashemi A. Validation of common reference genes stability in exosomal mRNA-isolated from liver and breast cancer cell lines. Cell Biol Int. 2021;45:1098-1110 pubmed publisher
Tu C, Du Z, Zhang H, Feng Y, Qi Y, Zheng Y, et al. Endocytic pathway inhibition attenuates extracellular vesicle-induced reduction of chemosensitivity to bortezomib in multiple myeloma cells. Theranostics. 2021;11:2364-2380 pubmed publisher
Dong L, Zieren R, Horie K, Kim C, Mallick E, Jing Y, et al. Comprehensive evaluation of methods for small extracellular vesicles separation from human plasma, urine and cell culture medium. J Extracell Vesicles. 2020;10:e12044 pubmed publisher
Li S, Stöckl S, Lukas C, Götz J, Herrmann M, Federlin M, et al. hBMSC-Derived Extracellular Vesicles Attenuate IL-1β-Induced Catabolic Effects on OA-Chondrocytes by Regulating Pro-inflammatory Signaling Pathways. Front Bioeng Biotechnol. 2020;8:603598 pubmed publisher
Chou S, Chan L, Chung C, Chiu J, Hsieh Y, Hong C. Altered Insulin Receptor Substrate 1 Phosphorylation in Blood Neuron-Derived Extracellular Vesicles From Patients With Parkinson's Disease. Front Cell Dev Biol. 2020;8:564641 pubmed publisher
Gorji Bahri G, Moghimi H, Hashemi A. RAB5A is associated with genes involved in exosome secretion: Integration of bioinformatics analysis and experimental validation. J Cell Biochem. 2021;122:425-441 pubmed publisher
Zhu X, Qin X, Wang X, Wang Y, Cao W, Zhang J, et al. Oral cancer cell‑derived exosomes modulate natural killer cell activity by regulating the receptors on these cells. Int J Mol Med. 2020;46:2115-2125 pubmed publisher
García Heredia J, Otero Albiol D, Perez M, Pérez Castejón E, Muñoz Galvan S, Carnero A. Breast tumor cells promotes the horizontal propagation of EMT, stemness, and metastasis by transferring the MAP17 protein between subsets of neoplastic cells. Oncogenesis. 2020;9:96 pubmed publisher
Zhang Z, Ge L, Zhang S, Wang J, Jiang W, Xin Q, et al. The protective effects of MSC-EXO against pulmonary hypertension through regulating Wnt5a/BMP signalling pathway. J Cell Mol Med. 2020;24:13938-13948 pubmed publisher
Rani K, Rastogi S, Vishwakarma P, Bharti P, Sharma V, Renu K, et al. A novel approach to correlate the salivary exosomes and their protein cargo in the progression of cognitive impairment into Alzheimer's disease. J Neurosci Methods. 2021;347:108980 pubmed publisher
Dobhal G, Datta A, Ayupova D, Teesdale Spittle P, Goreham R. Isolation, characterisation and detection of breath-derived extracellular vesicles. Sci Rep. 2020;10:17381 pubmed publisher
Li X, He X, Wang J, Wang D, Cong P, Zhu A, et al. The Regulation of Exosome-Derived miRNA on Heterogeneity of Macrophages in Atherosclerotic Plaques. Front Immunol. 2020;11:2175 pubmed publisher
Whittaker T, Nagelkerke A, Nele V, Kauscher U, Stevens M. Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles. J Extracell Vesicles. 2020;9:1807674 pubmed publisher
Elashiry M, Elashiry M, Elsayed R, Rajendran M, Auersvald C, Zeitoun R, et al. Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo. J Extracell Vesicles. 2020;9:1795362 pubmed publisher
Liang M, Chen X, Wang L, Qin L, Wang H, Sun Z, et al. Cancer-derived exosomal TRIM59 regulates macrophage NLRP3 inflammasome activation to promote lung cancer progression. J Exp Clin Cancer Res. 2020;39:176 pubmed publisher
Arteaga Blanco L, Mojoli A, Monteiro R, Sandim V, Menna Barreto R, Pereira Dutra F, et al. Characterization and internalization of small extracellular vesicles released by human primary macrophages derived from circulating monocytes. PLoS ONE. 2020;15:e0237795 pubmed publisher
Sorop A, Iacob R, Iacob S, Constantinescu D, Chitoiu L, Fertig T, et al. Plasma Small Extracellular Vesicles Derived miR-21-5p and miR-92a-3p as Potential Biomarkers for Hepatocellular Carcinoma Screening. Front Genet. 2020;11:712 pubmed publisher
Schroeder J, Puntigam L, Hofmann L, Jeske S, Beccard I, Doescher J, et al. Circulating Exosomes Inhibit B Cell Proliferation and Activity. Cancers (Basel). 2020;12: pubmed publisher
Le Gall L, Ouandaogo Z, Anakor E, Connolly O, Butler Browne G, Laine J, et al. Optimized method for extraction of exosomes from human primary muscle cells. Skelet Muscle. 2020;10:20 pubmed publisher
Im Y, Yoo H, Lee J, Park J, Suh G, Jeon K. Association of plasma exosomes with severity of organ failure and mortality in patients with sepsis. J Cell Mol Med. 2020;24:9439-9445 pubmed publisher
Kwon Y, Nukala S, Srivastava S, Miyamoto H, Ismail N, Rehman J, et al. Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells. bioRxiv. 2020;: pubmed publisher
Grzesiak M, Popiolek K, Knapczyk Stwora K. Extracellular vesicles in follicular fluid of sexually mature gilts' ovarian antral follicles - identification and proteomic analysis. J Physiol Pharmacol. 2020;71: pubmed publisher
Hofmann L, Ludwig S, Schuler P, Hoffmann T, Brunner C, Theodoraki M. The Potential of CD16 on Plasma-Derived Exosomes as a Liquid Biomarker in Head and Neck Cancer. Int J Mol Sci. 2020;21: pubmed publisher
Chaiwangyen W, Murrieta Coxca J, Favaro R, Photini S, Gutiérrez Samudio R, Schleussner E, et al. MiR-519d-3p in Trophoblastic Cells: Effects, Targets and Transfer to Allogeneic Immune Cells via Extracellular Vesicles. Int J Mol Sci. 2020;21: pubmed publisher
Sha J, Arbesman J, Harter M. Premature senescence in human melanocytes after exposure to solar UVR: An exosome and UV-miRNA connection. Pigment Cell Melanoma Res. 2020;33:671-684 pubmed publisher
Ke C, Hou H, Li J, Su K, Huang C, Lin Y, et al. Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib. Cancers (Basel). 2020;12: pubmed publisher
Horgan C, Nagelkerke A, Whittaker T, Nele V, Massi L, Kauscher U, et al. Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling. J Mater Chem B. 2020;8:4447-4459 pubmed publisher
Kauscher U, Penders J, Nagelkerke A, Holme M, Nele V, Massi L, et al. Gold Nanocluster Extracellular Vesicle Supraparticles: Self-Assembled Nanostructures for Three-Dimensional Uptake Visualization. Langmuir. 2020;36:3912-3923 pubmed publisher
Zieren R, Dong L, Pierorazio P, Pienta K, de Reijke T, Amend S. Extracellular vesicle isolation from human renal cancer tissue. Med Oncol. 2020;37:28 pubmed publisher
Mitchell A, Wanczyk H, JENSEN T, Finck C. Human induced pluripotent stem cells ameliorate hyperoxia-induced lung injury in a mouse model. Am J Transl Res. 2020;12:292-307 pubmed
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product information
Product Type :
Antibody
Product Name :
CD63 Monoclonal Antibody (Ts63)
Catalog # :
10628D
Quantity :
200 uL
Price :
US 336.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Western Blot: 2 ug/mL
Species :
Human
Clone :
Ts63
Isotype :
IgG1
Storage :
Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C
Description :
CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells. CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40. Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.
Immunogen :
CD63 purified from Jurkat and HEL cells
Format :
Liquid
Applications w/Dilutions :
Western Blot: 2 ug/mL
Aliases :
C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA