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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD9 Monoclonal Antibody (Ts9)
catalog :
10626D
quantity :
200 uL
price :
US 336.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Ts9
reactivity :
human, mouse
application :
western blot
more info or order :
citations: 75
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 2c
Kumar P, Zadjali F, Yao Y, Siroky B, Astrinidis A, Gross K, et al. Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles. Front Physiol. 2021;12:630933 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Iraci N, Gaude E, Leonardi T, Costa A, Cossetti C, Peruzzotti Jametti L, et al. Extracellular vesicles are independent metabolic units with asparaginase activity. Nat Chem Biol. 2017;13:951-955 pubmed publisher
  • western blot; human; fig s2a
Kishikawa T, Otsuka M, Yoshikawa T, Ohno M, Yamamoto K, Yamamoto N, et al. Quantitation of circulating satellite RNAs in pancreatic cancer patients. JCI Insight. 2016;1:e86646 pubmed publisher
Lin W, Wu H, Lee C, Chen Y, Huang L, Hui Chun Ho J, et al. Modulation of experimental acute lung injury by exosomal miR-7704 from mesenchymal stromal cells acts through M2 macrophage polarization. Mol Ther Nucleic Acids. 2024;35:102102 pubmed publisher
Lau H, Passalacqua I, Jung J, Kwon Y, Zocco D, Park S, et al. Unraveling the surface marker signature of cell-derived vesicles via proteome analysis and nanoparticle flow cytometry. Sci Rep. 2024;14:121 pubmed publisher
Huang C, Zhao Y, Lin S, Li L, Guo X, Yumiseba S, et al. Characterization of human placenta-derived exosome (pExo) as a potential osteoarthritis disease modifying therapeutic. Arthritis Res Ther. 2023;25:229 pubmed publisher
Paw M, Kusiak A, Nit K, Litewka J, Piejko M, Wnuk D, et al. Hypoxia enhances anti-fibrotic properties of extracellular vesicles derived from hiPSCs via the miR302b-3p/TGFβ/SMAD2 axis. BMC Med. 2023;21:412 pubmed publisher
Cross T, xd8 vsteb xf8 R, Brusletto B, Tr xf8 seid A, Olstad O, Aspelin T, et al. RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms. Int J Mol Sci. 2023;24: pubmed publisher
Takeda N, Tsuchiya A, Mito M, Natsui K, Natusi Y, Koseki Y, et al. Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis. Inflamm Regen. 2023;43:48 pubmed publisher
Kmiotek Wasylewska K, Bobis Wozowicz S, Karnas E, Orpel M, Wo x17a nicka O, Madeja Z, et al. Anti-inflammatory, Anti-fibrotic and Pro-cardiomyogenic Effects of Genetically Engineered Extracellular Vesicles Enriched in miR-1 and miR-199a on Human Cardiac Fibroblasts. Stem Cell Rev Rep. 2023;19:2756-2773 pubmed publisher
Cross T, Haug K, Brusletto B, Ommundsen S, Tr xf8 seid A, Aspelin T, et al. Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?. Int J Mol Sci. 2023;24: pubmed publisher
Affolter A, Liebel K, Tengler L, Seiz E, Tiedtke M, Azhakesan A, et al. Modulation of PD‑L1 expression by standard therapy in head and neck cancer cell lines and exosomes. Int J Oncol. 2023;63: pubmed publisher
Pendiuk Goncalves J, Walker S, Aguilar D xed az de Le xf3 n J, Yang Y, Davidovich I, Busatto S, et al. Glycan Node Analysis Detects Varying Glycosaminoglycan Levels in Melanoma-Derived Extracellular Vesicles. Int J Mol Sci. 2023;24: pubmed publisher
Tengler L, Sch xfc tz J, Tiedtke M, Jablonska J, Theodoraki M, Nitschke K, et al. Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patients. Mol Med. 2023;29:69 pubmed publisher
Bernuz M, Pallar xe8 s Rusi xf1 ol A, Rossi R, Fern xe1 ndez Senac C, Mart xed M, Pividori M. Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications. Methods Mol Biol. 2023;2668:257-276 pubmed publisher
Aas V, xd8 vsteb xf8 R, Brusletto B, Aspelin T, Tr xf8 seid A, Qureshi S, et al. Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation. Front Physiol. 2023;14:1143966 pubmed publisher
Cui H, Joo S, Lee S, Cho Y, Kim D, Seo C. Effect of Hypertrophic Scar Fibroblast-Derived Exosomes on Keratinocytes of Normal Human Skin. Int J Mol Sci. 2023;24: pubmed publisher
Meliciano A, Salvador D, Mendon xe7 a P, Louro A, Serra M. Clinically Expired Platelet Concentrates as a Source of Extracellular Vesicles for Targeted Anti-Cancer Drug Delivery. Pharmaceutics. 2023;15: pubmed publisher
Weber B, Henrich D, Schindler C, Marzi I, Leppik L. Release of exosomes in polytraumatized patients: The injury pattern is reflected by the surface epitopes. Front Immunol. 2023;14:1107150 pubmed publisher
Dash S, Wu C, Wu C, Chiang S, Lu Y, Yeh C, et al. Extracellular Vesicle Membrane Protein Profiling and Targeted Mass Spectrometry Unveil CD59 and Tetraspanin 9 as Novel Plasma Biomarkers for Detection of Colorectal Cancer. Cancers (Basel). 2022;15: pubmed publisher
Banks W, Sharma P, Hansen K, Ludwig N, Whiteside T. Characteristics of Exosomes and the Vascular Landscape Regulate Exosome Sequestration by Peripheral Tissues and Brain. Int J Mol Sci. 2022;23: pubmed publisher
Ta x15f l x131 P. Usage of celery root exosome as an immune suppressant; Lipidomic characterization of apium graveolens originated exosomes and its suppressive effect on PMA/ionomycin mediated CD4+ T lymphocyte activation. J Food Biochem. 2022;46:e14393 pubmed publisher
. Late Breaking Orals. J Extracell Vesicles. 2022;11:e12252 pubmed publisher
Wright A, Snyder O, Christenson L, He H, Weiss M. Effect of Pre-Processing Storage Condition of Cell Culture-Conditioned Medium on Extracellular Vesicles Derived from Human Umbilical Cord-Derived Mesenchymal Stromal Cells. Int J Mol Sci. 2022;23: pubmed publisher
Yang C, Hsu H, Liu Y, Tsai W, Ma C, Chen Y, et al. EV-miRome-wide profiling uncovers miR-320c for detecting metastatic colorectal cancer and monitoring the therapeutic response. Cell Oncol (Dordr). 2022;45:621-638 pubmed publisher
He N, Thippabhotla S, Zhong C, Greenberg Z, Xu L, Pessetto Z, et al. Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection. Commun Biol. 2022;5:660 pubmed publisher
Lee C, Chen Y, Hsiao A, Wang A, Shen O, Wang B, et al. Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells. J Adv Res. 2022;39:73-88 pubmed publisher
Cohn W, Zhu C, Campagna J, Bilousova T, Spilman P, Teter B, et al. Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue. Int J Mol Sci. 2022;23: pubmed publisher
van den Broek B, Wuyts C, Sisto A, Pintelon I, Timmermans J, Somers V, et al. Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles. Cell Commun Signal. 2022;20:58 pubmed publisher
Barnes B, Caws T, Thomas S, Shephard A, Corteling R, Hole P, et al. Investigating heparin affinity chromatography for extracellular vesicle purification and fractionation. J Chromatogr A. 2022;1670:462987 pubmed publisher
Moura S, Pallar xe8 s Rusi xf1 ol A, Sappia L, Mart xed M, Pividori M. The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design. Biosens Bioelectron. 2022;198:113826 pubmed publisher
Vestad B, Nyman T, Hove Skovsgaard M, Stensland M, Hoel H, Tr xf8 seid A, et al. Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk. Sci Rep. 2021;11:21936 pubmed publisher
Penders J, Nagelkerke A, Cunnane E, Pedersen S, Pence I, Coombes R, et al. Single Particle Automated Raman Trapping Analysis of Breast Cancer Cell-Derived Extracellular Vesicles as Cancer Biomarkers. ACS Nano. 2021;15:18192-18205 pubmed publisher
Elmore Z, Patrick Havlik L, Oh D, Anderson L, Daaboul G, Devlin G, et al. The membrane associated accessory protein is an adeno-associated viral egress factor. Nat Commun. 2021;12:6239 pubmed publisher
Qi Z, Xue Q, Wang H, Cao B, Su Y, Xing Q, et al. Serum CD203c+ Extracellular Vesicle Serves as a Novel Diagnostic and Prognostic Biomarker for Succinylated Gelatin Induced Perioperative Hypersensitive Reaction. Front Immunol. 2021;12:732209 pubmed publisher
Biadglegne F, Rademacher P, De Sulbaran Y, K xf6 nig B, Rodloff A, Zedler U, et al. Exosomes in serum‑free cultures of THP‑1 macrophages infected with Mycobacterium tuberculosis. Mol Med Rep. 2021;24: pubmed publisher
G x142 uszko A, Szczepa x144 ski M, Whiteside T, Reichert T, Siewiera J, Ludwig N. Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia. Cancers (Basel). 2021;13: pubmed publisher
Palinski W, Monti M, Camerlingo R, Iacobucci I, Bocella S, Pinto F, et al. Lysosome purinergic receptor P2X4 regulates neoangiogenesis induced by microvesicles from sarcoma patients. Cell Death Dis. 2021;12:797 pubmed publisher
Qi Z, Zhao Y, Su Y, Cao B, Yang J, Xing Q. Serum Extracellular Vesicle-Derived miR-124-3p as a Diagnostic and Predictive Marker for Early-Stage Acute Ischemic Stroke. Front Mol Biosci. 2021;8:685088 pubmed publisher
Kakiuchi Y, Kuroda S, Kanaya N, Kumon K, Tsumura T, Hashimoto M, et al. Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles. Mol Ther. 2021;29:2920-2930 pubmed publisher
Martínez Greene J, Hernández Ortega K, Quiroz Baez R, Resendis Antonio O, Pichardo Casas I, Sinclair D, et al. Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. J Extracell Vesicles. 2021;10:e12087 pubmed publisher
Li S, Stöckl S, Lukas C, Herrmann M, Brochhausen C, König M, et al. Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p. Stem Cell Res Ther. 2021;12:252 pubmed publisher
Busatto S, Iannotta D, Walker S, Di Marzio L, Wolfram J. A Simple and Quick Method for Loading Proteins in Extracellular Vesicles. Pharmaceuticals (Basel). 2021;14: pubmed publisher
Mondal S, Whiteside T. Immunoaffinity-Based Isolation of Melanoma Cell-Derived and T Cell-Derived Exosomes from Plasma of Melanoma Patients. Methods Mol Biol. 2021;2265:305-321 pubmed publisher
Nguyen S, Ahn S, Greenberg J, Collaer B, Agnew D, Arora R, et al. Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo. Sci Rep. 2021;11:4217 pubmed publisher
Schwartz R, Shokhirev M, Andrade L, Gutkind J, Iglesias Bartolomé R, Shadel G. Insights into epithelial cell senescence from transcriptome and secretome analysis of human oral keratinocytes. Aging (Albany NY). 2021;13:4747-4777 pubmed publisher
Kuypers S, Smisdom N, Pintelon I, Timmermans J, Ameloot M, Michiels L, et al. Unsupervised Machine Learning-Based Clustering of Nanosized Fluorescent Extracellular Vesicles. Small. 2021;17:e2006786 pubmed publisher
Niedermair T, Lukas C, Li S, Stöckl S, Craiovan B, Brochhausen C, et al. Influence of Extracellular Vesicles Isolated From Osteoblasts of Patients With Cox-Arthrosis and/or Osteoporosis on Metabolism and Osteogenic Differentiation of BMSCs. Front Bioeng Biotechnol. 2020;8:615520 pubmed publisher
Li S, Stöckl S, Lukas C, Götz J, Herrmann M, Federlin M, et al. hBMSC-Derived Extracellular Vesicles Attenuate IL-1β-Induced Catabolic Effects on OA-Chondrocytes by Regulating Pro-inflammatory Signaling Pathways. Front Bioeng Biotechnol. 2020;8:603598 pubmed publisher
Zhu X, Qin X, Wang X, Wang Y, Cao W, Zhang J, et al. Oral cancer cell‑derived exosomes modulate natural killer cell activity by regulating the receptors on these cells. Int J Mol Med. 2020;46:2115-2125 pubmed publisher
Whittaker T, Nagelkerke A, Nele V, Kauscher U, Stevens M. Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles. J Extracell Vesicles. 2020;9:1807674 pubmed publisher
Guerreiro E, Øvstebø R, Thiede B, Costea D, Søland T, Kanli Galtung H. Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics. PLoS ONE. 2020;15:e0238591 pubmed publisher
Walker S, Aguilar Díaz De León J, Busatto S, Wurtz G, Zubair A, Borges C, et al. Glycan Node Analysis of Plasma-Derived Extracellular Vesicles. Cells. 2020;9: pubmed publisher
Sorop A, Iacob R, Iacob S, Constantinescu D, Chitoiu L, Fertig T, et al. Plasma Small Extracellular Vesicles Derived miR-21-5p and miR-92a-3p as Potential Biomarkers for Hepatocellular Carcinoma Screening. Front Genet. 2020;11:712 pubmed publisher
Schroeder J, Puntigam L, Hofmann L, Jeske S, Beccard I, Doescher J, et al. Circulating Exosomes Inhibit B Cell Proliferation and Activity. Cancers (Basel). 2020;12: pubmed publisher
Hofmann L, Ludwig S, Schuler P, Hoffmann T, Brunner C, Theodoraki M. The Potential of CD16 on Plasma-Derived Exosomes as a Liquid Biomarker in Head and Neck Cancer. Int J Mol Sci. 2020;21: pubmed publisher
Sha J, Arbesman J, Harter M. Premature senescence in human melanocytes after exposure to solar UVR: An exosome and UV-miRNA connection. Pigment Cell Melanoma Res. 2020;33:671-684 pubmed publisher
Horgan C, Nagelkerke A, Whittaker T, Nele V, Massi L, Kauscher U, et al. Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling. J Mater Chem B. 2020;8:4447-4459 pubmed publisher
Seifert A, Düsterhöft S, Wozniak J, Koo C, Tomlinson M, Nuti E, et al. The metalloproteinase ADAM10 requires its activity to sustain surface expression. Cell Mol Life Sci. 2021;78:715-732 pubmed publisher
Reclusa P, Verstraelen P, Taverna S, Gunasekaran M, Pucci M, Pintelon I, et al. Improving extracellular vesicles visualization: From static to motion. Sci Rep. 2020;10:6494 pubmed publisher
Kauscher U, Penders J, Nagelkerke A, Holme M, Nele V, Massi L, et al. Gold Nanocluster Extracellular Vesicle Supraparticles: Self-Assembled Nanostructures for Three-Dimensional Uptake Visualization. Langmuir. 2020;36:3912-3923 pubmed publisher
Lima Moura S, Marti M, Pividori M. Matrix Effect in the Isolation of Breast Cancer-Derived Nanovesicles by Immunomagnetic Separation and Electrochemical Immunosensing-A Comparative Study. Sensors (Basel). 2020;20: pubmed publisher
Chen L, Feng Z, Yuan G, Emerson C, Stewart P, Ye F, et al. Human Immunodeficiency Virus-Associated Exosomes Promote Kaposi's Sarcoma-Associated Herpesvirus Infection via the Epidermal Growth Factor Receptor. J Virol. 2020;94: pubmed publisher
Ozawa P, Vieira E, Lemos D, Souza I, Zanata S, Pankievicz V, et al. Identification of miRNAs Enriched in Extracellular Vesicles Derived from Serum Samples of Breast Cancer Patients. Biomolecules. 2020;10: pubmed publisher
Zeh N, Schneider H, Mathias S, Raab N, Kleemann M, Schmidt Hertel S, et al. Human CAP cells represent a novel source for functional, miRNA-loaded exosome production. PLoS ONE. 2019;14:e0221679 pubmed publisher
Manini I, Ruaro M, Sgarra R, Bartolini A, Caponnetto F, Ius T, et al. Semaphorin-7A on Exosomes: A Promigratory Signal in the Glioma Microenvironment. Cancers (Basel). 2019;11: pubmed publisher
Bertolini I, Terrasi A, Martelli C, Gaudioso G, Di Cristofori A, Storaci A, et al. A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes. EBioMedicine. 2019;: pubmed publisher
Chen L, Feng Z, Yue H, Bazdar D, Mbonye U, Zender C, et al. Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA. Nat Commun. 2018;9:4585 pubmed publisher
Abramowicz A, Marczak L, Wojakowska A, Zapotoczny S, Whiteside T, Widlak P, et al. Harmonization of exosome isolation from culture supernatants for optimized proteomics analysis. PLoS ONE. 2018;13:e0205496 pubmed publisher
Guerreiro E, Vestad B, Steffensen L, Aass H, Saeed M, Øvstebø R, et al. Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography. PLoS ONE. 2018;13:e0204276 pubmed publisher
Middleton R, Rogers R, de Couto G, Tseliou E, Luther K, Holewinski R, et al. Newt cells secrete extracellular vesicles with therapeutic bioactivity in mammalian cardiomyocytes. J Extracell Vesicles. 2018;7:1456888 pubmed publisher
Bilousova T, Elias C, Miyoshi E, Alam M, Zhu C, Campagna J, et al. Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2. Biochem Biophys Res Commun. 2018;499:751-757 pubmed publisher
Saito S, Hiemori K, Kiyoi K, Tateno H. Glycome analysis of extracellular vesicles derived from human induced pluripotent stem cells using lectin microarray. Sci Rep. 2018;8:3997 pubmed publisher
Fang H, Shao S, Jiang M, Dang E, Shen S, Zhang J, et al. Proinflammatory role of blister fluid-derived exosomes in bullous pemphigoid. J Pathol. 2018;245:114-125 pubmed publisher
Kamalden T, Macgregor Das A, Kannan S, Dunkerly Eyring B, Khaliddin N, Xu Z, et al. Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress. Antioxid Redox Signal. 2017;27:913-930 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD9 Monoclonal Antibody (Ts9)
Catalog # :
10626D
Quantity :
200 uL
Price :
US 336.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Western Blot: 1 ug/mL
Species :
Human
Clone :
Ts9
Isotype :
IgG1
Storage :
Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C
Description :
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
Immunogen :
CD9 purified from HeLa cells
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1 ug/mL
Aliases :
5H9; 5H9 antigen; antigen CD9; BA2; BA-2/p24 antigen; BTCC-1; CD9; CD9 antigen; CD9 antigen (p24); CD9 molecule; cell growth-inhibiting gene 2 protein; DRAP-27; GIG2; Leukocyte antigen MIC3; MIC3; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin29; Tetraspanin-29; transmembrane protein CD9; TSPAN29; Tspan-29
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA