| Reference |
|---|
Abbott J, Tambe M, Pavlinov I, Farkhondeh A, Nguyen H, Xu M, et al. Generation and characterization of NGLY1 patient-derived midbrain organoids. Front Cell Dev Biol. 2023;11:1039182 pubmed publisher |
Kim J, Jeon J, Song B, Lee N, Ko S, Cha Y, et al. Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells. Nat Protoc. 2022;17:890-909 pubmed publisher |
Ngan S, Quach H, Laselva O, Huang E, Mangos M, Xia S, et al. Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function. Curr Protoc. 2022;2:e341 pubmed publisher |
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed publisher |
Pandya N, Wang C, Costa V, Lopatta P, Meier S, Zampeta F, et al. Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology. Cell Rep Med. 2021;2:100360 pubmed publisher |
Gao F, Klinedinst D, Fernandez F, Cheng B, Savonenko A, Devenney B, et al. Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates. Acta Neuropathol Commun. 2021;9:137 pubmed publisher |
Zabolocki M, McCormack K, van den Hurk M, Milky B, Shoubridge A, Adams R, et al. BrainPhys neuronal medium optimized for imaging and optogenetics in vitro. Nat Commun. 2020;11:5550 pubmed publisher |
Qin H, Zhao A, Sun M, Ma K, Fu X. Direct conversion of human fibroblasts into dopaminergic neuron-like cells using small molecules and protein factors. Mil Med Res. 2020;7:52 pubmed publisher |
Ebert L, Yu W, Gargett T, Toubia J, Kollis P, Tea M, et al. Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy. Clin Transl Immunology. 2020;9:e1191 pubmed publisher |
Chen M, Amado N, Tan J, Reis A, Ge M, Abreu J, et al. TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. elife. 2020;9: pubmed publisher |
Frame J, Kubaczka C, Long T, Esain V, Soto R, Hachimi M, et al. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Dev Cell. 2020;: pubmed publisher |
Okarmus J, Bogetofte H, Schmidt S, Ryding M, García López S, Ryan B, et al. Lysosomal perturbations in human dopaminergic neurons derived from induced pluripotent stem cells with PARK2 mutation. Sci Rep. 2020;10:10278 pubmed publisher |
Lee H, Lee H, Lee B, Gerovska D, Park S, Zaehres H, et al. Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model. elife. 2020;9: pubmed publisher |
Zhuang X, Wang S, Tan Y, Song J, Zhu Z, Wang Z, et al. Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson's disease models. Cell Death Dis. 2020;11:128 pubmed publisher |
Ke M, Chong C, Zeng H, Huang M, Huang Z, Zhang K, et al. Azoramide protects iPSC-derived dopaminergic neurons with PLA2G6 D331Y mutation through restoring ER function and CREB signaling. Cell Death Dis. 2020;11:130 pubmed publisher |
Xu R, Brawner A, Li S, Liu J, Kim H, Xue H, et al. OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Cell Stem Cell. 2019;: pubmed publisher |
Fan N, Ho T, Wu C, Tsao Y. Pigment epithelium-derived factor peptide promotes limbal stem cell proliferation through hedgehog pathway. J Cell Mol Med. 2019;23:4759-4769 pubmed publisher |
Zhao Y, Sun X, Hu D, Prosdocimo D, Hoppel C, Jain M, et al. ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects. Nat Commun. 2019;10:1371 pubmed publisher |
Zhu W, Zhang B, Li M, Mo F, Mi T, Wu Y, et al. Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome. Nat Commun. 2019;10:928 pubmed publisher |
Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher |
Wu M, Zhang D, Bi C, Mi T, Zhu W, Xia L, et al. A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs. Stem Cell Reports. 2018;11:635-650 pubmed publisher |
Zingg D, Debbache J, Peña Hernández R, Antunes A, Schaefer S, Cheng P, et al. EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation. Cancer Cell. 2018;34:69-84.e14 pubmed publisher |
Herrmann M, Anders S, Straub R, Jenei Lanzl Z. TNF inhibits catecholamine production from induced sympathetic neuron-like cells in rheumatoid arthritis and osteoarthritis in vitro. Sci Rep. 2018;8:9645 pubmed publisher |
Qian X, Jacob F, Song M, Nguyen H, Song H, Ming G. Generation of human brain region-specific organoids using a miniaturized spinning bioreactor. Nat Protoc. 2018;13:565-580 pubmed publisher |
Muratore C, Zhou C, Liao M, Fernandez M, Taylor W, Lagomarsino V, et al. Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability. Stem Cell Reports. 2017;9:1868-1884 pubmed publisher |
Bansal R, Nakagawa S, Yazdani S, van Baarlen J, Venkatesh A, Koh A, et al. Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases. Exp Mol Med. 2017;49:e396 pubmed publisher |
Dagklis A, Demeyer S, De Bie J, Radaelli E, Pauwels D, Degryse S, et al. Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors. Blood. 2016;128:2642-2654 pubmed |
Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed publisher |
Ng T, Yung J, Choy K, Cao D, Leung C, Cheung H, et al. Transdifferentiation of periodontal ligament-derived stem cells into retinal ganglion-like cells and its microRNA signature. Sci Rep. 2015;5:16429 pubmed publisher |
Rhim J, Luo X, Xu X, Gao D, Zhou T, Li F, et al. A High-content screen identifies compounds promoting the neuronal differentiation and the midbrain dopamine neuron specification of human neural progenitor cells. Sci Rep. 2015;5:16237 pubmed publisher |
Tian C, Li Y, Huang Y, Wang Y, Chen D, Liu J, et al. Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion. Sci Rep. 2015;5:12622 pubmed publisher |
Nieto Estévez V, Pignatelli J, Arauzo Bravo M, Hurtado Chong A, Vicario Abejón C. A global transcriptome analysis reveals molecular hallmarks of neural stem cell death, survival, and differentiation in response to partial FGF-2 and EGF deprivation. PLoS ONE. 2013;8:e53594 pubmed publisher |
Nefzger C, Su C, Fabb S, Hartley B, Beh S, Zeng W, et al. Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells. Stem Cells. 2012;30:1349-61 pubmed publisher |
Mellough C, Sernagor E, Moreno Gimeno I, Steel D, Lako M. Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells. Stem Cells. 2012;30:673-86 pubmed publisher |
Ngan E, Garcia Barcelo M, Yip B, Poon H, Lau S, Kwok C, et al. Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans. J Clin Invest. 2011;121:3467-78 pubmed publisher |
Nefzger C, Haynes J, Pouton C. Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells. Stem Cells. 2011;29:928-39 pubmed publisher |
