This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human TGF-beta 3 Recombinant Protein, PeproTech
catalog :
100-36E-100UG
quantity :
100 ug
price :
US 1204.00
citations: 102
Reference
Gao H, Huang X, Cai Z, Cai B, Wang K, Li J, et al. Generation of musculoskeletal cells from human urine epithelium-derived presomitic mesoderm cells. Cell Biosci. 2024;14:93 pubmed publisher
Khan N, Díaz Hernández M, Drissi H. Differentiation of Human Induced Pluripotent Stem Cells (iPSCs)-derived Mesenchymal Progenitors into Chondrocytes. Bio Protoc. 2023;13:e4874 pubmed publisher
Stahn L, Rasi x144 ska J, Dehne T, Schreyer S, Hakus A, Gossen M, et al. Sleeping Beauty transposon system for GDNF overexpression of entrapped stem cells in fibrin hydrogel in a rat model of Parkinson's disease. Drug Deliv Transl Res. 2023;13:1745-1765 pubmed publisher
Liang T, Li P, Liang A, Zhu Y, Qiu X, Qiu J, et al. Identifying the key genes regulating mesenchymal stem cells chondrogenic differentiation: an in vitro study. BMC Musculoskelet Disord. 2022;23:985 pubmed publisher
Shephard M, Merkhan M, Forsyth N. Human Mesenchymal Stem Cell Secretome Driven T Cell Immunomodulation Is IL-10 Dependent. Int J Mol Sci. 2022;23: pubmed publisher
Brachtl G, Poupardin R, Hochmann S, Raninger A, J xfc rchott K, Streitz M, et al. Batch Effects during Human Bone Marrow Stromal Cell Propagation Prevail Donor Variation and Culture Duration: Impact on Genotype, Phenotype and Function. Cells. 2022;11: pubmed publisher
Rasińska J, Klein C, Stahn L, Maidhof F, Pfeffer A, Schreyer S, et al. Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?. J Tissue Eng Regen Med. 2022;16:515-529 pubmed publisher
Jin Y, Liu Q, Chen P, Zhao S, Jiang W, Wang F, et al. A novel prostaglandin E receptor 4 (EP4) small molecule antagonist induces articular cartilage regeneration. Cell Discov. 2022;8:24 pubmed publisher
Rusilowicz Jones E, Barone F, Lopes F, Stephen E, Mortiboys H, Urb xe9 S, et al. Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy. Life Sci Alliance. 2022;5: pubmed publisher
Jarazo J, Barmpa K, Modamio J, Saraiva C, Sabat xe9 Soler S, Rosety I, et al. Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment. Mov Disord. 2022;37:80-94 pubmed publisher
Long Y, Bundkirchen K, Gr xe4 ff P, Krettek C, Noack S, Neunaber C. Cytological Effects of Serum Isolated from Polytraumatized Patients on Human Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells Int. 2021;2021:2612480 pubmed publisher
Casanova M, Os xf3 rio H, Reis R, Martins A, Neves N. Chondrogenic differentiation induced by extracellular vesicles bound to a nanofibrous substrate. NPJ Regen Med. 2021;6:79 pubmed publisher
Schrodi V, Neunaber C, Bundkirchen K, Ye W, Jiang Z, Petri M, et al. Characteristics of Mesenchymal Stem Cells Are Independent of Bone Marrow Storage Temperatures. Stem Cells Int. 2021;2021:6864988 pubmed publisher
Walter J, Bolognin S, Poovathingal S, Magni S, G xe9 rard D, Antony P, et al. The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Rep. 2021;37:109864 pubmed publisher
Chen R, Zhou X, Skutella T. A Tendon-Specific Double Reporter Transgenic Mouse Enables Tracking Cell Lineage and Functions Alteration In Vitro and In Vivo. Int J Mol Sci. 2021;22: pubmed publisher
Gustavsson N, Savchenko E, Klementieva O, Roybon L. The intracellular milieu of Parkinson's disease patient brain cells modulates alpha-synuclein protein aggregation. Acta Neuropathol Commun. 2021;9:153 pubmed publisher
Chen H, Xia K, Huang W, Li H, Wang C, Ma Y, et al. Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates. Cell Discov. 2021;7:75 pubmed publisher
Delaine Smith R, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones R, et al. Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer. iScience. 2021;24:102674 pubmed publisher
Shao R, Zhang Z, Xu Z, Ouyang H, Wang L, Ouyang H, et al. H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair. Bone Res. 2021;9:30 pubmed publisher
De Luzy I, Law K, Moriarty N, Hunt C, Durnall J, Thompson L, et al. Human stem cells harboring a suicide gene improve the safety and standardisation of neural transplants in Parkinsonian rats. Nat Commun. 2021;12:3275 pubmed publisher
Stykel M, Humphries K, Kamski Hennekam E, Buchner Duby B, Porte Trachsel N, Ryan T, et al. α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology. Cell Rep. 2021;35:109099 pubmed publisher
Woods S, Humphreys P, Bates N, Richardson S, Kuba S, Brooks I, et al. Regulation of TGFβ Signalling by TRPV4 in Chondrocytes. Cells. 2021;10: pubmed publisher
Guerrero J, H xe4 ckel S, Croft A, Albers C, Gantenbein B. The effects of 3D culture on the expansion and maintenance of nucleus pulposus progenitor cell multipotency. JOR Spine. 2021;4:e1131 pubmed publisher
Le Cann K, Foerster A, Rösseler C, Erickson A, Hautvast P, Giesselmann S, et al. The difficulty to model Huntington's disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells. Sci Rep. 2021;11:6934 pubmed publisher
Brown S, Boussaad I, Jarazo J, Fitzgerald J, Antony P, Keatinge M, et al. PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons. Sci Rep. 2021;11:6617 pubmed publisher
Ching K, Andriotis O, Sengers B, Stolz M. Genipin crosslinked chitosan/PEO nanofibrous scaffolds exhibiting an improved microenvironment for the regeneration of articular cartilage. J Biomater Appl. 2021;36:503-516 pubmed publisher
Zou L, Li J, Li H, Tan J, Wang M, Liu N, et al. TGF-β isoforms inhibit hepatitis C virus propagation in transforming growth factor beta/SMAD protein signalling pathway dependent and independent manners. J Cell Mol Med. 2021;25:3498-3510 pubmed publisher
Haag D, Mack N, Benites Goncalves da Silva P, Statz B, Clark J, Tanabe K, et al. H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model. Cancer Cell. 2021;: pubmed publisher
Machcinska S, Kopcewicz M, Bukowska J, Walendzik K, Gawronska Kozak B. Impairment of the Hif-1α regulatory pathway in Foxn1-deficient (Foxn1-/- ) mice affects the skin wound healing process. FASEB J. 2021;35:e21289 pubmed publisher
He J, Yan J, Wang J, Zhao L, Xin Q, Zeng Y, et al. Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses. Cell Res. 2021;31:742-757 pubmed publisher
Ruhl T, Schneider P, Kim B, Beier J. Endocannabinoids increase human adipose stem cell differentiation and growth factor secretion in vitro. J Tissue Eng Regen Med. 2021;15:88-98 pubmed publisher
Carlone D, Riba Wolman R, Deary L, Tovaglieri A, Jiang L, Ambruzs D, et al. Telomerase expression marks transitional growth-associated skeletal progenitor/stem cells. Stem Cells. 2021;39:296-305 pubmed publisher
Cornish A, Roychoudhury S, Sarma K, Pramanik S, Bhakat K, Dudley A, et al. Red panda: a novel method for detecting variants in single-cell RNA sequencing. BMC Genomics. 2020;21:830 pubmed publisher
Fukusumi H, Togo K, Sumida M, Nakamori M, Obika S, Baba K, et al. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication. FEBS Open Bio. 2021;11:354-366 pubmed publisher
Renner H, Grabos M, Becker K, Kagermeier T, Wu J, Otto M, et al. A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids. elife. 2020;9: pubmed publisher
Kinker G, Greenwald A, Tal R, Orlova Z, Cuoco M, McFarland J, et al. Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity. Nat Genet. 2020;52:1208-1218 pubmed publisher
Humphreys P, Woods S, Smith C, Bates N, Cain S, Lucas R, et al. Optogenetic Control of the BMP Signaling Pathway. ACS Synth Biol. 2020;9:3067-3078 pubmed publisher
Panagiotakopoulou V, Ivanyuk D, De Cicco S, Haq W, Arsic A, Yu C, et al. Interferon-γ signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells. Nat Commun. 2020;11:5163 pubmed publisher
Yao C, Haensel D, Gaddam S, Patel T, Atwood S, Sarin K, et al. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma. Nat Commun. 2020;11:5079 pubmed publisher
Schwartzentruber A, Boschian C, Lopes F, Myszczynska M, New E, Beyrath J, et al. Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons. Sci Rep. 2020;10:15485 pubmed publisher
Evans R, Antonelou M, Sathiananthamoorthy S, Rega M, Henderson S, Ceron Gutierrez L, et al. Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses. Nat Commun. 2020;11:4368 pubmed publisher
Takahashi K, Akatsu Y, Podyma Inoue K, Matsumoto T, Takahashi H, Yoshimatsu Y, et al. Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer. J Biol Chem. 2020;295:12559-12572 pubmed publisher
Barilani M, Cherubini A, Peli V, Polveraccio F, Bollati V, Guffanti F, et al. A circular RNA map for human induced pluripotent stem cells of foetal origin. EBioMedicine. 2020;57:102848 pubmed publisher
Zhao Y, Teng B, Sun X, Dong Y, Wang S, Hu Y, et al. Synergistic Effects of Kartogenin and Transforming Growth Factor-β3 on Chondrogenesis of Human Umbilical Cord Mesenchymal Stem Cells In Vitro. Orthop Surg. 2020;12:938-945 pubmed publisher
Vermilyea S, Babinski A, Tran N, To S, Guthrie S, Kluss J, et al. In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson's Disease in Common Marmosets. Sci Rep. 2020;10:3447 pubmed publisher
Zhang Y, Tang H, Liu C, Yuan X, Wang X, Ma N, et al. TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway. Mediators Inflamm. 2019;2019:3153240 pubmed publisher
Gantner C, De Luzy I, Kauhausen J, Moriarty N, Niclis J, Bye C, et al. Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease. Cell Stem Cell. 2020;26:511-526.e5 pubmed publisher
Gon xe7 alves A, Berdecka D, Rodrigues M, Eren A, de Boer J, Reis R, et al. Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose-derived stem cells. J Tissue Eng Regen Med. 2019;13:2204-2217 pubmed publisher
Xia S, Liu X, Cao X, Xu S. T-cell expression of Bruton's tyrosine kinase promotes autoreactive T-cell activation and exacerbates aplastic anemia. Cell Mol Immunol. 2020;17:1042-1052 pubmed publisher
Scheper V, Schwieger J, Hamm A, Lenarz T, Hoffmann A. BDNF-overexpressing human mesenchymal stem cells mediate increased neuronal protection in vitro. J Neurosci Res. 2019;97:1414-1429 pubmed publisher
Keller L, Pijnenburg L, Idoux Gillet Y, Bornert F, Benameur L, Tabrizian M, et al. Preclinical safety study of a combined therapeutic bone wound dressing for osteoarticular regeneration. Nat Commun. 2019;10:2156 pubmed publisher
Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity. 2019;: pubmed publisher
Mittal A, Rana S, Sharma R, Kumar A, Prasad R, Raut S, et al. Myocardin ablation in a cardiac-renal rat model. Sci Rep. 2019;9:5872 pubmed publisher
Cavalli E, Levinson C, Hertl M, Broguiere N, Brück O, Mustjoki S, et al. Characterization of polydactyly chondrocytes and their use in cartilage engineering. Sci Rep. 2019;9:4275 pubmed publisher
Lam T, Dehne T, Kr xfc ger J, Hondke S, Endres M, Thomas A, et al. Photopolymerizable gelatin and hyaluronic acid for stereolithographic 3D bioprinting of tissue-engineered cartilage. J Biomed Mater Res B Appl Biomater. 2019;107:2649-2657 pubmed publisher
Han Y, Feng H, Sun J, Liang X, Wang Z, Xing W, et al. Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation. J Clin Invest. 2019;130: pubmed publisher
McClellan A, Evans R, Sze C, Kan S, Paterson Y, Guest D. A novel mechanism for the protection of embryonic stem cell derived tenocytes from inflammatory cytokine interleukin 1 beta. Sci Rep. 2019;9:2755 pubmed publisher
Kane K, Moreno E, Hachi S, Walter M, Jarazo J, Oliveira M, et al. Automated microfluidic cell culture of stem cell derived dopaminergic neurons. Sci Rep. 2019;9:1796 pubmed publisher
Bolognin S, Fossépré M, Qing X, Jarazo J, Scancar J, Moreno E, et al. 3D Cultures of Parkinson's Disease-Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Adv Sci (Weinh). 2019;6:1800927 pubmed publisher
Stephenson S, Care M, Fan I, Zougman A, Westhead D, Doody G, et al. Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells. J Immunol. 2019;202:1287-1300 pubmed publisher
Bas E, Anwar M, Van De Water T. TGF β-1 and WNT Signaling Pathways Collaboration Associated with Cochlear Implantation Trauma-Induced Fibrosis. Anat Rec (Hoboken). 2020;303:608-618 pubmed publisher
Jang Y, Choi J, Park N, Kang J, Kim M, Kim Y, et al. Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering. Exp Mol Med. 2019;51:3 pubmed publisher
Rieder B, Weihs A, Weidinger A, Szwarc D, Nürnberger S, Redl H, et al. Hydrostatic pressure-generated reactive oxygen species induce osteoarthritic conditions in cartilage pellet cultures. Sci Rep. 2018;8:17010 pubmed publisher
Jayasuriya C, Twomey Kozak J, Newberry J, Desai S, Feltman P, Franco J, et al. Human Cartilage-Derived Progenitors Resist Terminal Differentiation and Require CXCR4 Activation to Successfully Bridge Meniscus Tissue Tears. Stem Cells. 2019;37:102-114 pubmed publisher
Lam J, Bellayr I, Marklein R, Bauer S, Puri R, Sung K. Functional Profiling of Chondrogenically Induced Multipotent Stromal Cell Aggregates Reveals Transcriptomic and Emergent Morphological Phenotypes Predictive of Differentiation Capacity. Stem Cells Transl Med. 2018;7:664-675 pubmed publisher
Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed publisher
Wang Y, Zhu W, Wu M, Wu Y, Liu Z, Liang L, et al. Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease. Stem Cell Reports. 2018;11:171-182 pubmed publisher
Taheem D, Foyt D, Loaiza S, Ferreira S, Ilic D, Auner H, et al. Differential Regulation of Human Bone Marrow Mesenchymal Stromal Cell Chondrogenesis by Hypoxia Inducible Factor-1α Hydroxylase Inhibitors. Stem Cells. 2018;36:1380-1392 pubmed publisher
Kim J, Lee J, Hwang H, Lee D, Park C, Jung S, et al. Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells. Exp Mol Med. 2018;50:24 pubmed publisher
Choi S, Xu Z, Li W, Yang H, Roopenian D, Morse H, et al. Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4+ T Cell Polarization. J Immunol. 2018;200:3087-3099 pubmed publisher
Christiansen Weber T, Noskov A, Cardiff D, Garitaonandia I, Dillberger A, Semechkin A, et al. Supplementation of specific carbohydrates results in enhanced deposition of chondrogenic-specific matrix during mesenchymal stem cell differentiation. J Tissue Eng Regen Med. 2018;12:1261-1272 pubmed publisher
Thiagarajan L, Abu Awwad H, Dixon J. Osteogenic Programming of Human Mesenchymal Stem Cells with Highly Efficient Intracellular Delivery of RUNX2. Stem Cells Transl Med. 2017;: pubmed publisher
Zhang M, Wang J, Deng C, Jiang M, Feng X, Xia K, et al. Transplanted human p75-positive stem Leydig cells replace disrupted Leydig cells for testosterone production. Cell Death Dis. 2017;8:e3123 pubmed publisher
Monzel A, Smits L, Hemmer K, Hachi S, Moreno E, van Wuellen T, et al. Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. 2017;8:1144-1154 pubmed publisher
Niclis J, Gantner C, Alsanie W, McDougall S, Bye C, Elefanty A, et al. Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents. Stem Cells Transl Med. 2017;6:937-948 pubmed publisher
Borgs L, Peyre E, Alix P, Hanon K, Grobarczyk B, Godin J, et al. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep. 2016;6:33377 pubmed publisher
Frisch J, Venkatesan J, Rey Rico A, Zawada A, Schmitt G, Madry H, et al. Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates. J Exp Orthop. 2016;3:16 pubmed publisher
Pizzute T, Li J, Zhang Y, Davis M, Pei M. Fibroblast Growth Factor Ligand Dependent Proliferation and Chondrogenic Differentiation of Synovium-Derived Stem Cells and Concomitant Adaptation of Wnt/Mitogen-Activated Protein Kinase Signals. Tissue Eng Part A. 2016;22:1036-46 pubmed publisher
Mak J, Jablonski C, Leonard C, Dunn J, Raharjo E, Matyas J, et al. Intra-articular injection of synovial mesenchymal stem cells improves cartilage repair in a mouse injury model. Sci Rep. 2016;6:23076 pubmed publisher
Jiang H, Xu Z, Zhong P, Ren Y, Liang G, Schilling H, et al. Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons. Nat Commun. 2015;6:10100 pubmed publisher
Bedinger D, Lao L, Khan S, Lee S, Takeuchi T, Mirza A. Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms. MAbs. 2016;8:389-404 pubmed publisher
Ribeiro T, Duarte A, Longhini A, Pradella F, Farias A, Luzo A, et al. Neuroprotection and immunomodulation by xenografted human mesenchymal stem cells following spinal cord ventral root avulsion. Sci Rep. 2015;5:16167 pubmed publisher
Palm T, Bolognin S, Meiser J, Nickels S, Träger C, Meilenbrock R, et al. Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. Sci Rep. 2015;5:16321 pubmed publisher
Riemenschneider M, Hirblinger M, Vollmann Zwerenz A, Hau P, Proescholdt M, Jaschinski F, et al. TGF-ß isoforms in cancer: Immunohistochemical expression and Smad-pathway-activity-analysis in thirteen major tumor types with a critical appraisal of antibody specificity and immunohistochemistry assay validity. Oncotarget. 2015;6:26770-81 pubmed publisher
Barter M, Tselepi M, Gómez R, Woods S, Hui W, Smith G, et al. Genome-Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR-140-5p. Stem Cells. 2015;33:3266-80 pubmed publisher
Li Y, El Mozen L, Cai H, Fang W, Meng Q, Li J, et al. Transforming growth factor beta 3 involved in the pathogenesis of synovial chondromatosis of temporomandibular joint. Sci Rep. 2015;5:8843 pubmed publisher
Jiang M, Cai B, Tuo Y, Wang J, Zang Z, Tu X, et al. Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction. Cell Res. 2014;24:1466-85 pubmed publisher
Lai J, Kajiyama G, Smith R, Maloney W, Yang F. Stem cells catalyze cartilage formation by neonatal articular chondrocytes in 3D biomimetic hydrogels. Sci Rep. 2013;3:3553 pubmed publisher
Jones M, Varella Garcia M, Skokan M, Bryce S, Schowinsky J, Peters R, et al. Genetic stability of bone marrow-derived human mesenchymal stromal cells in the Quantum System. Cytotherapy. 2013;15:1323-39 pubmed publisher
Martino M, Briquez P, Ranga A, Lutolf M, Hubbell J. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Proc Natl Acad Sci U S A. 2013;110:4563-8 pubmed publisher
Nguyen J, Tang S, Nguyen D, Alliston T. Load regulates bone formation and Sclerostin expression through a TGF?-dependent mechanism. PLoS ONE. 2013;8:e53813 pubmed publisher
Tang R, Gao M, Wu M, Liu H, Zhang X, Liu B. High glucose mediates endothelial-to-chondrocyte transition in human aortic endothelial cells. Cardiovasc Diabetol. 2012;11:113 pubmed publisher
Krawetz R, Wu Y, Martin L, Rattner J, Matyas J, Hart D. Synovial fluid progenitors expressing CD90+ from normal but not osteoarthritic joints undergo chondrogenic differentiation without micro-mass culture. PLoS ONE. 2012;7:e43616 pubmed publisher
Yoshida M, Okubo N, Chosa N, Hasegawa T, Ibi M, Kamo M, et al. TGF-?-operated growth inhibition and translineage commitment into smooth muscle cells of periodontal ligament-derived endothelial progenitor cells through Smad- and p38 MAPK-dependent signals. Int J Biol Sci. 2012;8:1062-74 pubmed publisher
Allen J, Cooke M, Alliston T. ECM stiffness primes the TGF? pathway to promote chondrocyte differentiation. Mol Biol Cell. 2012;23:3731-42 pubmed
Lee D, Yoon W, Cho E, Kim H, Gronostajski R, Cho M, et al. Crosstalk between nuclear factor I-C and transforming growth factor-?1 signaling regulates odontoblast differentiation and homeostasis. PLoS ONE. 2011;6:e29160 pubmed publisher
Devine M, Ryten M, Vodicka P, Thomson A, Burdon T, Houlden H, et al. Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus. Nat Commun. 2011;2:440 pubmed publisher
Fan G, Wen L, Li M, Li C, Luo B, Wang F, et al. Isolation of mouse mesenchymal stem cells with normal ploidy from bone marrows by reducing oxidative stress in combination with extracellular matrix. BMC Cell Biol. 2011;12:30 pubmed publisher
Qin J, Li W, Zhang L, Chen F, Liang W, Mao F, et al. A stem cell-based tool for small molecule screening in adipogenesis. PLoS ONE. 2010;5:e13014 pubmed publisher
Mendez Ferrer S, Michurina T, Ferraro F, Mazloom A, MacArthur B, Lira S, et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 2010;466:829-34 pubmed publisher
Tran D, Andersson J, Wang R, Ramsey H, Unutmaz D, Shevach E. GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A. 2009;106:13445-50 pubmed publisher
Vogel T, Ahrens S, Büttner N, Krieglstein K. Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. Cereb Cortex. 2010;20:661-71 pubmed publisher
product information
Product Type :
Protein
Product Name :
Human TGF-beta 3 Recombinant Protein, PeproTech
Catalog # :
100-36E-100UG
Quantity :
100 ug
Price :
US 1204.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Storage :
-20 C
Description :
Transforming growth factor beta 3 (TGF beta 3) is the third member of the transforming growth factor family of cytokines, which also includes TGF beta 1 and beta 2. These cytokines are secreted in precursor form consisting of a bioactive C-terminal domain attached to an N-terminal domain known as latency associated protein (LAP). Cleavage of LAP results in the mature protein, which functions as a disulfide-linked homodimer. As with all members of the family, TGF beta 3 is highly conserved across species, with mouse and human TGF beta 3 demonstrating 100% sequence homology and cross-species activity.The members of this family can be expressed by most cell types and exert pleiotropic effects, which include the suppression of B- and T-cell effector activity, mediation of tissue healing, and suppression of tumor proliferation. The promotion of CD4+CD25+ T-cell expansion is a newly discovered function of the TGF beta cytokines, and indicates an important role in the protection against autoimmunity.
Format :
Lyophilized
Applications w/Dilutions :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Aliases :
ARVD; ARVD1; FLJ16571; H-TGF-b-3; LAP; Latency-associated peptide; LDS5; prepro-transforming growth factor beta-3; RNHF; TGF beta 3; Tgfb3; TGF-B3; Tgfb-3; TGF-beta3; TGF-beta-3; Transforming growth factor; transforming growth factor beta 3; transforming growth factor beta precursor; transforming growth factor beta-3; Transforming growth factor beta-3 proprotein; transforming growth factor, beta 3; transforming growth factor-beta3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA