Human TGF-alpha Recombinant Protein, PeproTech | Invitrogen 100-16A-500UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human TGF-alpha Recombinant Protein, PeproTech

catalog :

100-16A-500UG

quantity :

500 ug

price :

US 766.00

citations: 34

Reference
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Wolf C, Qian Y, Brooke M, Kelsell D, Franzke C. ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phospholipase C γ1 and protein kinase C pathways. Sci Rep. 2016;6:39780 pubmed publisher
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Amatngalim G, van Wijck Y, de Mooij Eijk Y, Verhoosel R, Harder J, Lekkerkerker A, et al. Basal cells contribute to innate immunity of the airway epithelium through production of the antimicrobial protein RNase 7. J Immunol. 2015;194:3340-50 pubmed publisher
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Krall J, Beyer E, MacBeath G. High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways. PLoS ONE. 2011;6:e15945 pubmed publisher
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product information

Product Type :

Protein

Product Name :

Human TGF-alpha Recombinant Protein, PeproTech

Catalog # :

100-16A-500UG

Quantity :

500 ug

Price :

US 766.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Format :

Lyophilized

Applications w/Dilutions :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Aliases :

EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1