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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MSH6 Monoclonal Antibody (44)
catalog :
08-1374
quantity :
6 mL
price :
US 399.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
44
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human
Baiocchi G, Portolani N, Vermi W, Baronchelli C, Gheza F, Zogno C, et al. Lynch syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old. BMC Surg. 2014;14:9 pubmed publisher
  • immunohistochemistry - paraffin section; human
Gatalica Z, Lilleberg S, Monzon F, Koul M, Bridge J, Knezetic J, et al. Renal medullary carcinomas: histopathologic phenotype associated with diverse genotypes. Hum Pathol. 2011;42:1979-88 pubmed publisher
  • immunohistochemistry - paraffin section; human
Cossio S, Koehler Santos P, Pessini S, Mónego H, Edelweiss M, Meurer L, et al. Clinical and histomolecular endometrial tumor characterization of patients at-risk for Lynch syndrome in South of Brazil. Fam Cancer. 2010;9:131-9 pubmed publisher
  • immunohistochemistry - paraffin section; human
Arabi H, Guan H, Kumar S, Cote M, Bandyopadhyay S, Bryant C, et al. Impact of microsatellite instability (MSI) on survival in high grade endometrial carcinoma. Gynecol Oncol. 2009;113:153-8 pubmed publisher
  • immunohistochemistry - paraffin section; human
Mylona E, Zarogiannos A, Nomikos A, Giannopoulou I, Nikolaou I, Zervas A, et al. Prognostic value of microsatellite instability determined by immunohistochemical staining of hMSH2 and hMSH6 in urothelial carcinoma of the bladder. APMIS. 2008;116:59-65 pubmed publisher
Millen R, Hendry S, Narasimhan V, Abbott R, Croxford M, Gibbs P, et al. CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival. Clin Transl Immunology. 2020;9:e1155 pubmed publisher
product information
Product Type :
Antibody
Product Name :
MSH6 Monoclonal Antibody (44)
Catalog # :
08-1374
Quantity :
6 mL
Price :
US 399.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): Assay-dependent
Species :
Human
Clone :
44
Isotype :
IgG1
Storage :
4 C
Description :
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.
Immunogen :
Fusion protein derived from human muscle.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): Assay-dependent
Aliases :
AU044881; AW550279; cb326; DNA mismatch repair protein Msh6; g/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC5; HSAP; LOC100360342; mismatch repair protein Msh6; Msh6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; mutS homolog 6; mutS homolog 6 (E. coli); MutS protein homolog 6; MutS-alpha 160 kDa subunit; MutS-alpha 160kDa subunit; p160; rCG61559-like; Sperm associated protein; sperm-associated protein; wu:fb36c12
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA