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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD56 Monoclonal Antibody (123C3)
catalog :
07-5603
quantity :
100 µg
price :
US 380
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
123C3
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...
Nakamura A, Mitsuhashi T, Takano Y, Miyoshi H, Kameda H, Nomoto H, et al. Usefulness of the octreotide test in Japanese patients for predicting the presence/absence of somatostatin receptor 2 expression in insulinomas. Endocr J. 2016;63:135-42 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1
Marković Lipkovski J, Životić M, Müller C, Tampe B, Ćirović S, Vještica J, et al. Variable Expression of Neural Cell Adhesion Molecule Isoforms in Renal Tissue: Possible Role in Incipient Renal Fibrosis. PLoS ONE. 2015;10:e0137028 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50-1:100; fig 4
Ceyran A, Şenol S, Şimşek B, Sağıroğlu J, Aydın A. Role of cd56 and e-cadherin expression in the differential diagnosis of papillary thyroid carcinoma and suspected follicular-patterned lesions of the thyroid: the prognostic importance of e-cadherin. Int J Clin Exp Pathol. 2015;8:3670-80 pubmed
  • immunohistochemistry; mouse; 1:400; fig 1,2,4,5
Zerboni L, Arvin A. Neuronal Subtype and Satellite Cell Tropism Are Determinants of Varicella-Zoster Virus Virulence in Human Dorsal Root Ganglia Xenografts In Vivo. PLoS Pathog. 2015;11:e1004989 pubmed publisher
  • immunohistochemistry; human; fig s4a
Chang N, Gu J, Gu S, Osorio R, Concepcion W, Gu E. Arterial flow regulator enables transplantation and growth of human fetal kidneys in rats. Am J Transplant. 2015;15:1692-700 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 3
Kurisaki Arakawa A, Saito T, Takahashi M, Mitani K, Yao T. A case of (123)I-MIBG scintigram-negative functioning pheochromocytoma: immunohistochemical and molecular analysis with review of literature. Int J Clin Exp Pathol. 2014;7:4438-47 pubmed
  • immunohistochemistry - paraffin section; human; 1:100
Yang Y, Li Y, Liu Y, Yang M, Liu K. CD30+ extranodal natural killer/T-cell lymphoma mimicking phlegmonous myositis: A case report. Oncol Lett. 2014;7:1419-1421 pubmed
  • immunohistochemistry; human; 1:200; fig 1
Wilkens J, Male V, Ghazal P, Forster T, Gibson D, Williams A, et al. Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil. J Immunol. 2013;191:2226-35 pubmed publisher
  • immunohistochemistry; human; 1:50
Karagkounis G, Argyrakos T, Charkiolakis G, Castana O, Rontogianni D. A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125. Case Rep Pathol. 2013;2013:312786 pubmed publisher
  • immunohistochemistry - paraffin section; human
Zuo Z, Tang Y, Bi C, Zhang W, Zhao S, Wang X, et al. Extraosseous (extramedullary) plasmacytomas: a clinicopathologic and immunophenotypic study of 32 Chinese cases. Diagn Pathol. 2011;6:123 pubmed publisher
  • flow cytometry; human; 1:100; tbl 3
Su X, Huang J, Jiang Y, Tang Y, Li G, Liu W. Serous effusion cytology of extranodal natural killer/T-cell lymphoma. Cytopathology. 2012;23:96-102 pubmed publisher
  • immunohistochemistry; human; fig 3
Lee D, Yang J, Lee S, Won C, Chang S, Lee M, et al. Subcutaneous panniculitis-like T-cell lymphoma: a clinical and pathologic study of 14 korean patients. Ann Dermatol. 2011;23:329-37 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Yong Jiang -, Huawei Liu -, Hu Long -, Yingying Yang -, Dianying Liao -, Xiuhui Zhang -. Goblet cell carcinoid of the appendix: a clinicopathological and immunohistochemical study of 26 cases from southwest china. Int J Surg Pathol. 2010;18:488-92 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 1
Baiker A, Fabel K, Cozzio A, Zerboni L, Fabel K, Sommer M, et al. Varicella-zoster virus infection of human neural cells in vivo. Proc Natl Acad Sci U S A. 2004;101:10792-7 pubmed
  • immunohistochemistry - paraffin section; human; fig 2
Doubrovina E, Doubrovin M, Vider E, Sisson R, O Reilly R, Dupont B, et al. Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J Immunol. 2003;171:6891-9 pubmed
  • immunohistochemistry; human; 1:40
Nakatsuka S, Liu A, Dong Z, Nomura S, Takakuwa T, Miyazato H, et al. Simian virus 40 sequences in malignant lymphomas in Japan. Cancer Res. 2003;63:7606-8 pubmed
Johnson B, Creason A, Stommel J, Keck J, Parmar S, Betts C, et al. An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer. Cell Rep Med. 2022;3:100525 pubmed publisher
Schwabenland M, Salié H, Tanevski J, Killmer S, Lago M, Schlaak A, et al. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions. Immunity. 2021;54:1594-1610.e11 pubmed publisher
He M, Wang Y, Zhang G, Cao K, Yang M, Liu H. The prognostic significance of tumor-infiltrating lymphocytes in cervical cancer. J Gynecol Oncol. 2021;32:e32 pubmed publisher
Nishiyama K, Watanabe Y, Ishimura M, Tetsuhara K, Imai T, Kanemasa H, et al. Parvovirus B19-Infected Tubulointerstitial Nephritis in Hereditary Spherocytosis. Open Forum Infect Dis. 2020;7:ofaa288 pubmed publisher
Garzia L, Kijima N, Morrissy A, De Antonellis P, Guerreiro Stucklin A, Holgado B, et al. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 2018;172:1050-1062.e14 pubmed publisher
Celik B, Bulut T. Human epididymis protein 4 may not be a reliable screening biomarker for detecting lung carcinoma patients. Biomed Rep. 2017;7:297-300 pubmed publisher
George J, Saito M, Tsuta K, Iwakawa R, Shiraishi K, Scheel A, et al. Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer. Clin Cancer Res. 2017;23:1220-1226 pubmed publisher
Jeon Y, Kim J, Sung J, Han J, Ko Y. Epstein-Barr virus-positive nodal T/NK-cell lymphoma: an analysis of 15 cases with distinct clinicopathological features. Hum Pathol. 2015;46:981-90 pubmed publisher
Tomasini D, Niccoli A, Crivelli F. Pagetoid reticulosis tumor cells with double expression of TCRγδ and TCRαβ: an off-target phenomenon or genuine expression?. J Cutan Pathol. 2015;42:427-34 pubmed publisher
Thompson L, Bauer J, Chiosea S, McHugh J, Seethala R, Miettinen M, et al. Canalicular adenoma: a clinicopathologic and immunohistochemical analysis of 67 cases with a review of the literature. Head Neck Pathol. 2015;9:181-95 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD56 Monoclonal Antibody (123C3)
Catalog # :
07-5603
Quantity :
100 µg
Price :
US 380
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 2 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: 2-5 µg, Western Blot: Assay-dependent
Species :
Human
Clone :
123C3
Isotype :
IgG1
Storage :
-20°C
Description :
CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
Immunogen :
SCLC membrane preparation
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 2 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: 2-5 µg, Western Blot: Assay-dependent
Aliases :
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA