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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Caveolin 1 Monoclonal Antibody (Z034)
catalog :
03-6000
quantity :
100 µg
price :
US 500
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Z034
reactivity :
hamsters, human, mouse, rat, bovine
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
Cobbe N, Marshall K, Gururaja Rao S, Chang C, Di Cara F, Duca E, et al. The conserved metalloprotease invadolysin localizes to the surface of lipid droplets. J Cell Sci. 2009;122:3414-23 pubmed publisher
  • immunocytochemistry; mouse
Lajoie P, Partridge E, Guay G, Goetz J, Pawling J, Lagana A, et al. Plasma membrane domain organization regulates EGFR signaling in tumor cells. J Cell Biol. 2007;179:341-56 pubmed
  • western blot; bovine; fig 6
Czarny M, Schnitzer J. Neutral sphingomyelinase inhibitor scyphostatin prevents and ceramide mimics mechanotransduction in vascular endothelium. Am J Physiol Heart Circ Physiol. 2004;287:H1344-52 pubmed
  • western blot; human
Duxbury M, Ito H, Ashley S, Whang E. CEACAM6 cross-linking induces caveolin-1-dependent, Src-mediated focal adhesion kinase phosphorylation in BxPC3 pancreatic adenocarcinoma cells. J Biol Chem. 2004;279:23176-82 pubmed
  • immunoprecipitation; hamsters; fig 4
  • western blot; hamsters; fig 4
Razandi M, Alton G, Pedram A, Ghonshani S, Webb P, Levin E. Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane. Mol Cell Biol. 2003;23:1633-46 pubmed
  • immunohistochemistry - frozen section; rat
Voldstedlund M, Vinten J, Tranum Jensen J. cav-p60 expression in rat muscle tissues. Distribution of caveolar proteins. Cell Tissue Res. 2001;306:265-76 pubmed
Ressnerova A, Novotný F, Michalkova H, Pumera M, Adam V, Heger Z. Efficient Protein Transfection by Swarms of Chemically Powered Plasmonic Virus-Sized Nanorobots. ACS Nano. 2021;15:12899-12910 pubmed publisher
Wu J, Liu J, Qu C, Wang Y, Zhu Y, Zhang Y, et al. Study of immune responses in mice to oral administration of Flor·Essence. Mol Clin Oncol. 2020;12:533-540 pubmed publisher
Zhu H, Yue J, Pan Z, Wu H, Cheng Y, Lu H, et al. Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. PLoS ONE. 2010;5:e12055 pubmed publisher
Zulli A, Lau E, Wijaya B, Jin X, Sutarga K, Schwartz G, et al. High dietary taurine reduces apoptosis and atherosclerosis in the left main coronary artery: association with reduced CCAAT/enhancer binding protein homologous protein and total plasma homocysteine but not lipidemia. Hypertension. 2009;53:1017-22 pubmed publisher
Navarro Garc xed a F, Canizalez Roman A, Vidal J, Salazar M. Intoxication of epithelial cells by plasmid-encoded toxin requires clathrin-mediated endocytosis. Microbiology (Reading). 2007;153:2828-2838 pubmed publisher
Leon Sicairos N, Reyes Lopez M, Canizalez Roman A, Bermúdez Cruz R, Serrano Luna J, Arroyo R, et al. Human hololactoferrin: endocytosis and use as an iron source by the parasite Entamoeba histolytica. Microbiology. 2005;151:3859-71 pubmed
Pol A, Martin S, Fernandez M, Ingelmo Torres M, Ferguson C, Enrich C, et al. Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies. Mol Biol Cell. 2005;16:2091-105 pubmed
product information
Product Type :
Antibody
Product Name :
Caveolin 1 Monoclonal Antibody (Z034)
Catalog # :
03-6000
Quantity :
100 µg
Price :
US 500
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Immunocytochemistry: 2-4 µg/mL, Immunoprecipitation: 2-5 µg/mL, Western Blot: 0.5-2.0 µg/mL
Species :
Human
Clone :
Z034
Isotype :
IgG1
Storage :
-20°C
Description :
Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
Immunogen :
Tyrosine-phosphorylated proteins from RSV-transformed chick embryo fibroblasts
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2-4 µg/mL, Immunoprecipitation: 2-5 µg/mL, Western Blot: 0.5-2.0 µg/mL
Aliases :
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA