product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Annexin A2 Monoclonal Antibody (Z014)
catalog :
03-4400
quantity :
100 µg
price :
US 430
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Z014
reactivity :
human, mouse, dogs, bovine, domestic sheep
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...
  • flow cytometry; mouse; 1:50; loading ...; fig 6a
Renner B, Tong H, Laskowski J, Jonscher K, Goetz L, Woolaver R, et al. Annexin A2 Enhances Complement Activation by Inhibiting Factor H. J Immunol. 2016;196:1355-65 pubmed publisher
  • blocking or activating experiments; human; 25 ug/ml
Hastie C, Masters J, Moss S, Naaby Hansen S. Interferon-gamma reduces cell surface expression of annexin 2 and suppresses the invasive capacity of prostate cancer cells. J Biol Chem. 2008;283:12595-603 pubmed publisher
  • blocking or activating experiments; human; fig 1
Pluskota E, Soloviev D, Bdeir K, Cines D, Plow E. Integrin alphaMbeta2 orchestrates and accelerates plasminogen activation and fibrinolysis by neutrophils. J Biol Chem. 2004;279:18063-72 pubmed
  • western blot; human; 0.125 ug/ml
  • western blot; mouse; 0.125 ug/ml; fig 6
Brownstein C, Deora A, Jacovina A, Weintraub R, Gertler M, Khan K, et al. Annexin II mediates plasminogen-dependent matrix invasion by human monocytes: enhanced expression by macrophages. Blood. 2004;103:317-24 pubmed
  • western blot; bovine
Liu L, Enright E, Sun P, Tsai S, Mehta P, Beckman D, et al. Inactivation of annexin II tetramer by S-nitrosoglutathione. Eur J Biochem. 2002;269:4277-86 pubmed
  • western blot; human; fig 1
Aarli A, Kristoffersen E, Jensen T, Ulvestad E, Matre R. Suppressive effect on lymphoproliferation in vitro by soluble annexin II released from isolated placental membranes. Am J Reprod Immunol. 1997;38:313-9 pubmed
Liu B, Xing Z, Song F, Li D, Zhao B, Xu C, et al. METTL3-mediated ANXA2 inhibition confers neuroprotection in ischemic stroke: Evidence from in vivo and in vitro studies. FASEB J. 2023;37:e22974 pubmed publisher
Yonglitthipagon P, Pairojkul C, Chamgramol Y, Mulvenna J, Sripa B. Up-regulation of annexin A2 in cholangiocarcinoma caused by Opisthorchis viverrini and its implication as a prognostic marker. Int J Parasitol. 2010;40:1203-12 pubmed publisher
Zhou H, Ling S, Yu Y, Wang T, Hu H. Involvement of annexin A2 in anti-beta2GPI/beta2GPI-induced tissue factor expression on monocytes. Cell Res. 2007;17:737-9 pubmed
Deora A, Kreitzer G, Jacovina A, Hajjar K. An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface. J Biol Chem. 2004;279:43411-8 pubmed
product information
Product Type :
Antibody
Product Name :
Annexin A2 Monoclonal Antibody (Z014)
Catalog # :
03-4400
Quantity :
100 µg
Price :
US 430
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Bovine, Canine, Human, Ovine
Applications :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5 µg, Immunohistochemistry: 5-10 µg/mL, Western Blot: 0.5-1.0 µg/mL
Species :
Bovine, Canine, Human, Ovine
Clone :
Z014
Isotype :
IgG1
Storage :
-20°C
Description :
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen :
Annexin II purified from bovine lung.
Format :
Liquid
Applications w/Dilutions :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5 µg, Immunohistochemistry: 5-10 µg/mL, Western Blot: 0.5-1.0 µg/mL
Aliases :
33-kDa calcimedin; 33-kDa lymphocyte Ca - binding protein; 33kDa lymphocyte Ca - binding protein; 36-kDa calelectrin; annexin 2; annexin A2; annexin A2 isoform 2; annexin II; Annexin-2; ANX2; ANX2L4; ANXA2; AW215814; CAL1H; calpactin I heavy chain; calpactin I heavy chain (p36); calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; HEL-S-270; LIP2; lipocortin II; LPC2; LPC2D; p36; PAP-IV; Placental anticoagulant protein IV; protein I
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA