BrdU Monoclonal Antibody (ZBU30), Biotin | Invitrogen 03-3940 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BrdU Monoclonal Antibody (ZBU30), Biotin

catalog :

03-3940

quantity :

1 mL

price :

US 450

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

ZBU30

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 9

Reference
Lin K, Qiang W, Zhu M, Ding Y, Shi Q, Chen X, et al. Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Cell Rep. 2019;26:2434-2450.e6 pubmed publisher
Lin K, Zhang S, Shi Q, Zhu M, Gao L, Xia W, et al. Essential requirement of mammalian Pumilio family in embryonic development. Mol Biol Cell. 2018;29:2922-2932 pubmed publisher
Finger T, Bartel D, Shultz N, Goodson N, Greer C. 5HTR3A-driven GFP labels immature olfactory sensory neurons. J Comp Neurol. 2017;525:1743-1755 pubmed publisher
Chen L, Faire M, Kissner M, Laird D. Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele. Hum Mol Genet. 2013;22:313-27 pubmed publisher
Lu Y, Lou Y, Bernard J, Peng Q, Li T, Lin Y, et al. Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet. Proc Natl Acad Sci U S A. 2012;109:9065-70 pubmed publisher
Xu X, Zhou Y, Wang M. Mechanisms of cytoplasmic {beta}-catenin accumulation and its involvement in tumorigenic activities mediated by oncogenic splicing variant of the receptor originated from Nantes tyrosine kinase. J Biol Chem. 2005;280:25087-94 pubmed
Crnic I, Strittmatter K, Cavallaro U, Kopfstein L, Jussila L, Alitalo K, et al. Loss of neural cell adhesion molecule induces tumor metastasis by up-regulating lymphangiogenesis. Cancer Res. 2004;64:8630-8 pubmed
Cases S, Zhou P, Shillingford J, Wiseman B, Fish J, Angle C, et al. Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues. Development. 2004;131:3047-55 pubmed
Ding J, Xu X, Yang D, Chu P, Dalton N, Ye Z, et al. Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J. 2004;23:885-96 pubmed

product information

Product Type :

Antibody

Product Name :

BrdU Monoclonal Antibody (ZBU30), Biotin

Catalog # :

03-3940

Quantity :

1 mL

Price :

US 450

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Chemical

Applications :

Immunohistochemistry: Assay-dependent

Species :

Chemical

Clone :

ZBU30

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.

Immunogen :

BrdU

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-dependent

Aliases :

5-Bromo-2-deoxyuridine; Bromodeoxyuridine

more info or order :

Invitrogen product webpage