BrdU Monoclonal Antibody (ZBU30) | Invitrogen 03-3900 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BrdU Monoclonal Antibody (ZBU30)

catalog :

03-3900

quantity :

400 µg

price :

US 430

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZBU30

reactivity :

African green monkey, mouse

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 29

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig 2a	Jeong H, Lim K, Goldenring J, Nam K. Rab25 Deficiency Perturbs Epidermal Differentiation and Skin Barrier Function in Mice. Biomol Ther (Seoul). 2019;27:553-561 pubmed publisher
immunocytochemistry; mouse; 1:25; loading ...; fig 3c	Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf Klingebiel M, Gigina A, et al. The transcription factor GATA4 promotes myocardial regeneration in neonatal mice. EMBO Mol Med. 2017;9:265-279 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100; fig 5	Wang G, Yan Q, Woods A, Aubrey L, Feng Q, Beier F. Inducible nitric oxide synthase-nitric oxide signaling mediates the mitogenic activity of Rac1 during endochondral bone growth. J Cell Sci. 2011;124:3405-13 pubmed publisher
immunohistochemistry - paraffin section; mouse	Holtz M, Misra R. Serum response factor is required for cell contact maintenance but dispensable for proliferation in visceral yolk sac endothelium. BMC Dev Biol. 2011;11:18 pubmed publisher
immunocytochemistry; African green monkey; fig 7	Chong D, Paton J, Thorpe C, Paton A. Clathrin-dependent trafficking of subtilase cytotoxin, a novel AB5 toxin that targets the endoplasmic reticulum chaperone BiP. Cell Microbiol. 2008;10:795-806 pubmed
	Spina E, Simundza J, Incassati A, Chandramouli A, Kugler M, Lin Z, et al. Gpr125 is a unifying hallmark of multiple mammary progenitors coupled to tumor latency. Nat Commun. 2022;13:1421 pubmed publisher
	Choi Y, Song M, Jung W, Jeong H, Park S, Yang B, et al. Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling. Cell Mol Gastroenterol Hepatol. 2021;12:1761-1787 pubmed publisher
	Lin K, Qiang W, Zhu M, Ding Y, Shi Q, Chen X, et al. Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Cell Rep. 2019;26:2434-2450.e6 pubmed publisher
	Xiang X, Langlois S, St Pierre M, Barré J, Grynspan D, Purgina B, et al. Pannexin 1 inhibits rhabdomyosarcoma progression through a mechanism independent of its canonical channel function. Oncogenesis. 2018;7:89 pubmed publisher
	Rhodes C, Zunino G, Huang S, Cardona S, Cardona A, Berger M, et al. Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches. Cell Cycle. 2018;17:377-389 pubmed publisher
	Haye Bertolozzi J, Aparicio O. Quantitative Bromodeoxyuridine Immunoprecipitation Analyzed by High-Throughput Sequencing (qBrdU-Seq or QBU). Methods Mol Biol. 2018;1672:209-225 pubmed publisher
	Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, et al. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis. Nat Commun. 2017;8:584 pubmed publisher
	Kadmiel M, Matson B, Espenschied S, Lenhart P, Caron K. Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation. PLoS ONE. 2017;12:e0181597 pubmed publisher
	Peace J, Villwock S, Zeytounian J, Gan Y, Aparicio O. Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase. Genome Res. 2016;26:365-75 pubmed publisher
	Murlidharan G, Corriher T, Ghashghaei H, Asokan A. Unique glycan signatures regulate adeno-associated virus tropism in the developing brain. J Virol. 2015;89:3976-87 pubmed publisher
	He P, Staufenbiel M, Li R, Shen Y. Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice. Hum Mol Genet. 2014;23:6512-27 pubmed publisher
	Alvers A, Ryan S, Scherz P, Huisken J, Bagnat M. Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling. Development. 2014;141:1110-9 pubmed publisher
	Beiriger A, Sears K. Cellular basis of differential limb growth in postnatal gray short-tailed opossums (Monodelphis domestica). J Exp Zool B Mol Dev Evol. 2014;322:221-9 pubmed publisher
	Kolander K, Holtz M, Cossette S, Duncan S, Misra R. Epicardial GATA factors regulate early coronary vascular plexus formation. Dev Biol. 2014;386:204-15 pubmed publisher
	Sobek S, Dalla Rosa I, Pommier Y, Bornholz B, Kalfalah F, Zhang H, et al. Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I. Nucleic Acids Res. 2013;41:9848-57 pubmed publisher
	Liu B, Staron M, Hong F, Wu B, Sun S, Morales C, et al. Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway. Proc Natl Acad Sci U S A. 2013;110:6877-82 pubmed publisher
	Yan Q, Feng Q, Beier F. Endothelial nitric oxide synthase deficiency in mice results in reduced chondrocyte proliferation and endochondral bone growth. Arthritis Rheum. 2010;62:2013-22 pubmed publisher
	McLennan R, Teddy J, Kasemeier Kulesa J, Romine M, Kulesa P. Vascular endothelial growth factor (VEGF) regulates cranial neural crest migration in vivo. Dev Biol. 2010;339:114-25 pubmed publisher
	Chen Y, Collins L, Uno H, Chang C. Deficits in motor coordination with aberrant cerebellar development in mice lacking testicular orphan nuclear receptor 4. Mol Cell Biol. 2005;25:2722-32 pubmed
	Agrotis A, Kanellakis P, Kostolias G, Di Vitto G, Wei C, Hannan R, et al. Proliferation of neointimal smooth muscle cells after arterial injury. Dependence on interactions between fibroblast growth factor receptor-2 and fibroblast growth factor-9. J Biol Chem. 2004;279:42221-9 pubmed
	Curcio A, Torella D, Cuda G, Coppola C, Faniello M, Achille F, et al. Effect of stent coating alone on in vitro vascular smooth muscle cell proliferation and apoptosis. Am J Physiol Heart Circ Physiol. 2004;286:H902-8 pubmed
	Jiang Z, Wu L, Miller B, Goldman D, Fernandez C, Abouhamze Z, et al. A novel vein graft model: adaptation to differential flow environments. Am J Physiol Heart Circ Physiol. 2004;286:H240-5 pubmed
	Wali R, Khare S, Tretiakova M, Cohen G, Nguyen L, Hart J, et al. Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin. Cancer Epidemiol Biomarkers Prev. 2002;11:1653-62 pubmed
	Berg D, Lynch N, Lynch R, Lauricella D. Rapid development of severe hyperplastic gastritis with gastric epithelial dedifferentiation in Helicobacter felis-infected IL-10(-/-) mice. Am J Pathol. 1998;152:1377-86 pubmed

product information

Product Type :

Antibody

Product Name :

BrdU Monoclonal Antibody (ZBU30)

Catalog # :

03-3900

Quantity :

400 µg

Price :

US 430

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Chemical

Applications :

Immunohistochemistry: Assay-dependent

Species :

Chemical

Clone :

ZBU30

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.

Immunogen :

BrdU

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-dependent

Aliases :

5-Bromo-2-deoxyuridine; Bromodeoxyuridine

more info or order :

Invitrogen product webpage