RasGRP2-pSer587 | Immunoglobe 0222-020 product information

product summary

company name :

Immunoglobe

product type :

antibody

product name :

RasGRP2-pSer587

catalog :

0222-020

quantity :

100 µl, 20 µg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog, cow

application :

western blot

more info or order :

Immunoglobe product webpage

product information

CATALOG NO :

0222-020

NAME (Link To Web Site) :

IG-1209

SPECIFICITY :

RasGRP2-pSer587

OTHER NAMES :

Ras guanyl releasing protein 2 (calcium and DAG-regulated) pSer587, RAS guanyl nucleotide-releasing protein 2 pSer587, Calcium and DAG-regulated guanine nucleotide exchange factor I pSer587, CalDAG-GEFI pSer587, F25B3.3 kinase-like protein pSer587, guanine exchange factor MCG7 pSer587, MCG7 pSer587, hCDC25L pSer587, cdc25-like protein pSer587

UniProt / Swiss-Prot # :

Q2YDB1

CLONE/Poly-clonal :

polyclonal

HOST SPECIES :

RABBIT

reactive species :

tested: human, mouse; sequence identity: rat, Chinese hamster, guinea pig, dog, cat, pig, cow, sheep, diverse/other

FORMAT/CONJUGATES :

affinity purified on the antigen

SIZE :

100 µl, 20 µg

DESCRIPTION :

The synthetic phospho-peptide used as an antigen corresponds to a partial sequence of human RasGRP2 (CalDAG-GEFI) containing the phosphorylated serine [pS] of the following sequence stretch: …SFSLPRPGRRG[pS]RPPE-IREEEVQTV… Depending on the isoform, this residue is designated either as pSer587 (69.2 kDa isoform 1), or pSer649 (75.5 kDa isoform 2). pSer586 is the equivalent site in mouse and rat RasGRP2.

APPLICATIONS :

WB - Western blot

SAMPLE APPLICATIONS :

Human (5 μg protein/lane) and mouse platelets (8 μg/lane) were either not stimulated (−) or were incubated with 5 μM Forskolin for 1 min (+). Blot membranes were probed with the indicated dilutions of phospho-specific rabbit anti-GRP2-pSer587 antibody IG-

SUGGESTED DILUTIONS :

WB: 1:2,000 (100 ng/ml)

Updated :

6/14/16

more info or order :

Immunoglobe product webpage