product summary
Loading...
company name :
Immunoglobe
product type :
antibody
product name :
survival of motor neuron (SMN)
catalog :
0176-01
quantity :
500 µl, 1.0 mg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7B10
reactivity :
human
more info or order :
citations: 14
Reference |
---|
Narayanan U, Achsel T, Luhrmann R, Matera A. Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein. Mol Cell. 2004;16:223-34 pubmed
|
Voss M, Hille A, Barth S, Spurk A, Hennrich F, Holzer D, et al. Functional cooperation of Epstein-Barr virus nuclear antigen 2 and the survival motor neuron protein in transactivation of the viral LMP1 promoter. J Virol. 2001;75:11781-90 pubmed
|
Meister G, Buhler D, Laggerbauer B, Zobawa M, Lottspeich F, Fischer U. Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins. Hum Mol Genet. 2000;9:1977-86 pubmed
|
Narayanan U, Ospina J, Frey M, Hebert M, Matera A. SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta. Hum Mol Genet. 2002;11:1785-95 pubmed
|
Grimmler M, Bauer L, Nousiainen M, Körner R, Meister G, Fischer U. Phosphorylation regulates the activity of the SMN complex during assembly of spliceosomal U snRNPs. EMBO Rep. 2005;6:70-6 pubmed
|
Meister G, Pillai R, Lottspeich F, Fischer U. A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs. Nat Cell Biol. 2001;3:945-9 pubmed
|
Hebert M, Shpargel K, Ospina J, Tucker K, Matera A. Coilin methylation regulates nuclear body formation. Dev Cell. 2002;3:329-37 pubmed
|
Pillai R, Grimmler M, Meister G, Will C, Luhrmann R, Fischer U, et al. Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes Dev. 2003;17:2321-33 pubmed
|
Petri S, Grimmler M, Over S, Fischer U, Gruss O. Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complex. J Cell Biol. 2007;179:451-65 pubmed
|
Kroiss M, Brünger K, Wiesner J, Grimmler M, Sickmann A, Fischer U. Native purification of protein and RNA-protein complexes using a novel affinity procedure. Fly (Austin). 2009;3:221-8 pubmed
|
Jones K, Gorzynski K, Hales C, Fischer U, Badbanchi F, Terns R, et al. Direct interaction of the spinal muscular atrophy disease protein SMN with the small nucleolar RNA-associated protein fibrillarin. J Biol Chem. 2001;276:38645-51 pubmed
|
Grimmler M, Otter S, Peter C, Müller F, Chari A, Fischer U. Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization. Hum Mol Genet. 2005;14:3099-111 pubmed
|
Otter S, Grimmler M, Neuenkirchen N, Chari A, Sickmann A, Fischer U. A comprehensive interaction map of the human survival of motor neuron (SMN) complex. J Biol Chem. 2007;282:5825-33 pubmed
|
product information
CATALOG NO :
0176-01
NAME (Link To Web Site) :
7B10
SPECIFICITY :
survival of motor neuron (SMN)
OTHER NAMES :
SMN, BCD541, Component of gems 1, Gemin-1, SMA1 / SAM 2 / SMA3 / SMA4, SMN1 / SMN2, SMNC, SMNT, Survival motor neuron protein, T-BCD541
UniProt / Swiss-Prot # :
Q16637, A8K0V4, Q96J51
CLONE/Poly-clonal :
monoclonal, 7B10
HOST SPECIES :
MOUSE
ISOTYPE :
IgG1
reactive species :
human
FORMAT/CONJUGATES :
purified, carrier-free
SIZE :
500 µl, 1.0 mg
DESCRIPTION :
antibody raised against recombinant protein (full-length sequence); detailed information on epitope available; synthetic epitope peptide for competition / control / elution experiments available as product #0179-01 ("TagIt")
APPLICATIONS :
WB - Western blot / immunoblot, IP - immunoprecipitation, affinity isolation / purification of native tagged protein and RNA-protein complexes
SAMPLE APPLICATIONS :
Native purification of protein and RNA-protein complexes using a novel affinity procedure
[PubMed-Id; PMID] :
15592453, 16159890, 12361597, 11509571, 19690462, 18621711, 11715014, 10942426, 15494309, 12095920, 17178713, 17984321, 12975319, 11689659
Updated :
4/19/13
more info or order :
company information

Immunoglobe
info@immunoGlobe.com
www.immunoglobe.comrelated products
browse more products
questions and comments