Lat-2 | Immunoglobe 0142-10 product information

product summary

company name :

Immunoglobe

product type :

antibody

product name :

Lat-2

catalog :

0142-10

quantity :

100 µg, 200 µl

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

Immunoglobe product webpage

citations: 3

Reference
Wittmann G, Mohácsik P, Balkhi M, Gereben B, Lechan R. Endotoxin-induced inflammation down-regulates L-type amino acid transporter 1 (LAT1) expression at the blood-brain barrier of male rats and mice. Fluids Barriers CNS. 2015;12:21 pubmed publisher
Wirth E, Roth S, Blechschmidt C, Holter S, Becker L, Racz I, et al. Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome. J Neurosci. 2009;29:9439-49 pubmed publisher
Braun D, Wirth E, Wohlgemuth F, Reix N, Klein M, Gruters A, et al. Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter Slc7a8. Biochem J. 2011;439:249-55 pubmed publisher

product information

CATALOG NO :

0142-10

NAME (Link To Web Site) :

Lat-2, Slc7a8

SPECIFICITY :

Lat-2

OTHER NAMES :

Lat 2, Slc7a8

UniProt / Swiss-Prot # :

Q9QXW9

CLONE/Poly-clonal :

polyclonal

HOST SPECIES :

RABBIT

reactive species :

human, mouse

FORMAT/CONJUGATES :

affinity purified on the antigen

SIZE :

100 µg, 200 µl

DESCRIPTION :

The antibody detects a ~ 50 kDa Lat 2 band in wild type mouse brain, kidney, jejunum, ileum, and other tissues, which is absent in knock-out animals. In some tissues the antibody labels an additional unknown 38 kDa band [Braun et al. 2011].

APPLICATIONS :

WB - Western blot, immunoblot, IF - immunofluorescence, IHC - immuno-histochemistry

SAMPLE APPLICATIONS :

Western blot (mouse kidney)

SUGGESTED DILUTIONS :

WB: 1:1,000 (0.5 µg/ml); IHC: 1:250 (2 µg/ml)

[PubMed-Id; PMID] :

21726201, 19641107

Updated :

3/11/15

more info or order :

Immunoglobe product webpage